메뉴 건너뛰기




Volumn 12, Issue 4, 2009, Pages 183-188

Association between leptin receptor (LEPR) and brain-derived neurotrophic factor (BDNF) gene variants and obesity: A case-control study

Author keywords

Brain derived neurotrophic factor; Case control study; Leptin receptor; Obesity

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; LEPTIN RECEPTOR;

EID: 70350435972     PISSN: 1028415X     EISSN: 14768305     Source Type: Journal    
DOI: 10.1179/147683009X423355     Document Type: Article
Times cited : (17)

References (35)
  • 3
    • 59849128464 scopus 로고    scopus 로고
    • Genetics of obesity in humans
    • Farooqi IS, O'Rahilly S. Genetics of obesity in humans. Endocr Rev 2006; 22: 221-226.
    • (2006) Endocr Rev , vol.22 , pp. 221-226
    • Farooqi, I.S.1    O'rahilly, S.2
  • 5
    • 3142731898 scopus 로고    scopus 로고
    • The critical role of the melanocortin system in the control of energy intake
    • Seeley RJ, Drazen DL, Clegg DJ. The critical role of the melanocortin system in the control of energy intake. Annu Rev Nutr 2004; 24: 133-149.
    • (2004) Annu Rev Nutr , vol.24 , pp. 133-149
    • Seeley, R.J.1    Drazen, D.L.2    Clegg, D.J.3
  • 6
    • 0037456768 scopus 로고    scopus 로고
    • Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
    • Farooqi IS, Keogh JM, Yeo GSH et al. Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. N Engl J Med 2003; 348: 1085-1095.
    • (2003) N Engl J Med , vol.348 , pp. 1085-1095
    • Farooqi, I.S.1    Keogh, J.M.2    Yeo, G.S.H.3
  • 7
    • 33846409122 scopus 로고    scopus 로고
    • Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor
    • Farooqi IS, Wangensteen T, Collins S et al. Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor. N Engl J Med 2007; 356: 237-247.
    • (2007) N Engl J Med , vol.356 , pp. 237-247
    • Farooqi, I.S.1    Wangensteen, T.2    Collins, S.3
  • 8
    • 23444460111 scopus 로고    scopus 로고
    • Genetics of leptin and obesity: A HuGE review
    • Paracchini V, Pedotti P, Taioli E. Genetics of leptin and obesity: a HuGE review. Am J Epidemiol 2005; 162: 101-114.
    • (2005) Am J Epidemiol , vol.162 , pp. 101-114
    • Paracchini, V.1    Pedotti, P.2    Taioli, E.3
  • 9
    • 33847017334 scopus 로고    scopus 로고
    • Common genetic variations in CCK, leptin, and leptin receptor genes are associated with specific human eating patterns
    • De Krom M, van der Schouw YT, Hendriks J et al. Common genetic variations in CCK, leptin, and leptin receptor genes are associated with specific human eating patterns. Diabetes 2007; 56: 276-280.
    • (2007) Diabetes , vol.56 , pp. 276-280
    • De Krom, M.1    Van Der Schouw, Y.T.2    Hendriks, J.3
  • 10
    • 44349142294 scopus 로고    scopus 로고
    • Common variants near MC4R are associated with fat mass, weight and risk of obesity
    • Loos RJ, Lindgren CM, Li S et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008; 40: 768-775.
    • (2008) Nat Genet , vol.40 , pp. 768-775
    • Loos, R.J.1    Lindgren, C.M.2    Li, S.3
  • 11
    • 0038392755 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor
    • Xu B, Goulding EH, Zang K et al. Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat Neurosci 2003; 6: 736-742.
    • (2003) Nat Neurosci , vol.6 , pp. 736-742
    • Xu, B.1    Goulding, E.H.2    Zang, K.3
  • 12
    • 50449091503 scopus 로고    scopus 로고
    • The power of the extreme in elucidating obesity
    • Froguel P, Blakemore AIF. The power of the extreme in elucidating obesity. N Engl J Med 2008; 359: 891-893.
    • (2008) N Engl J Med , vol.359 , pp. 891-893
    • Froguel, P.1    Blakemore, A.I.F.2
  • 13
    • 37549055474 scopus 로고    scopus 로고
    • Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity
    • Unger TJ, Calderon GA, Bradley LC et al. Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity. J Neurosci 2007; 27: 14265-14274.
    • (2007) J Neurosci , vol.27 , pp. 14265-14274
    • Unger, T.J.1    Calderon, G.A.2    Bradley, L.C.3
  • 14
    • 33845530762 scopus 로고    scopus 로고
    • Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene
    • Gray J, Yeo GS, Cox JJ et al. Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene. Diabetes 2006; 55: 3366-3371.
    • (2006) Diabetes , vol.55 , pp. 3366-3371
    • Gray, J.1    Yeo, G.S.2    Cox, J.J.3
  • 15
    • 7044262828 scopus 로고    scopus 로고
    • A de novo mutation affecting human TrkB associated with severe obesity and developmental delay
    • Yeo GS, Connie Hung CC, Rochford J et al. A de novo mutation affecting human TrkB associated with severe obesity and developmental delay. Nat Neurosci 2004; 7: 1187-1189.
    • (2004) Nat Neurosci , vol.7 , pp. 1187-1189
    • Yeo, G.S.1    Connie Hung, C.C.2    Rochford, J.3
  • 16
    • 50449091665 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor in the WAGR syndrome
    • Han JC, Liu QR, Jones MP et al. Brain-derived neurotrophic factor in the WAGR syndrome. N Engl J Med 2008; 359: 918-927.
    • (2008) N Engl J Med , vol.359 , pp. 918-927
    • Han, J.C.1    Liu, Q.R.2    Jones, M.P.3
  • 17
    • 17744403132 scopus 로고    scopus 로고
    • Obesity risk is associated with carbohydrate intake in women carrying the Gln27Glu beta2-adrenoceptor polymorphism
    • Martinez JA, Corbalán MS, Sánchez-Villegas A et al. Obesity risk is associated with carbohydrate intake in women carrying the Gln27Glu beta2-adrenoceptor polymorphism. J Nutr 2003; 133: 2549-2554.
    • (2003) J Nutr , vol.133 , pp. 2549-2554
    • Martinez, J.A.1    Corbalán, M.S.2    Sánchez-Villegas, A.3
  • 18
    • 0025720531 scopus 로고
    • Human and rat brain-derived neurotrophic factor and neurotrophin-3: Gene structures, distributions, and chromosomal localizations
    • Maisonpierre PC, Le Beau MM, Espinosa R et al. Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations. Genomics 1991; 10: 558-568.
    • (1991) Genomics , vol.10 , pp. 558-568
    • Maisonpierre, P.C.1    Le Beau, M.M.2    Espinosa, R.3
  • 19
    • 47249097896 scopus 로고    scopus 로고
    • BDNF variability in opioid addicts and response to methadone treatment: Preliminary findings
    • De Cid R, Fonseca F, Gratacos M et al. BDNF variability in opioid addicts and response to methadone treatment: preliminary findings. Genes Brain Behav 2008; 7: 512-522.
    • (2008) Genes Brain Behav , vol.7 , pp. 512-522
    • De Cid, R.1    Fonseca, F.2    Gratacos, M.3
  • 20
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 21
    • 41649094148 scopus 로고    scopus 로고
    • Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data
    • Dudbridge F. Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Hum Hered 2008; 66: 87-98.
    • (2008) Hum Hered , vol.66 , pp. 87-98
    • Dudbridge, F.1
  • 23
    • 34247855844 scopus 로고    scopus 로고
    • A novel mutation Thr162Arg of the melanocortin 4 receptor gene in a Spanish children and adolescent population
    • Ochoa MC, Azcona C, Biebermann H et al. A novel mutation Thr162Arg of the melanocortin 4 receptor gene in a Spanish children and adolescent population. Clin Endocrinol 2007; 66: 652-658.
    • (2007) Clin Endocrinol , vol.66 , pp. 652-658
    • Ochoa, M.C.1    Azcona, C.2    Biebermann, H.3
  • 24
    • 50449099144 scopus 로고    scopus 로고
    • Lessons from extreme human obesity: Monogenic disorders
    • Ranadive SA, Vaisse C. Lessons from extreme human obesity: monogenic disorders. Endocrinol Metab Clin North Am 2008; 37: 733-751.
    • (2008) Endocrinol Metab Clin North Am , vol.37 , pp. 733-751
    • Ranadive, S.A.1    Vaisse, C.2
  • 25
    • 18344396039 scopus 로고    scopus 로고
    • A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference
    • Heo M, Leibel RL, Fontaine KR et al. A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference. Int J Obes 2002; 26: 640-646.
    • (2002) Int J Obes , vol.26 , pp. 640-646
    • Heo, M.1    Leibel, R.L.2    Fontaine, K.R.3
  • 26
    • 19944429689 scopus 로고    scopus 로고
    • Mutation screen of the brain derived neurotrophic factor gene (BDNF): Identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder
    • Friedel S, Horro FF, Wermter AK et al. Mutation screen of the brain derived neurotrophic factor gene (BDNF): identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet 2005; 5: 96-99.
    • (2005) Am J Med Genet B Neuropsychiatr Genet , vol.5 , pp. 96-99
    • Friedel, S.1    Horro, F.F.2    Wermter, A.K.3
  • 27
    • 51849117596 scopus 로고    scopus 로고
    • Association of the BDNF Val66Met variation with obesity in women
    • Beckers S, Peeters A, Zegers D et al. Association of the BDNF Val66Met variation with obesity in women. Mol Genet Metab 2008; 95: 110-112.
    • (2008) Mol Genet Metab , vol.95 , pp. 110-112
    • Beckers, S.1    Peeters, A.2    Zegers, D.3
  • 28
    • 33744958340 scopus 로고    scopus 로고
    • BDNF Val66Met polymorphism is associated with body mass index in healthy adults
    • Gunstad J, Schofield P, Paul RH et al. BDNF Val66Met polymorphism is associated with body mass index in healthy adults. Neuropsychobiology 2006; 53: 153-156.
    • (2006) Neuropsychobiology , vol.53 , pp. 153-156
    • Gunstad, J.1    Schofield, P.2    Paul, R.H.3
  • 29
    • 10744223605 scopus 로고    scopus 로고
    • Met66 in the brainderived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type
    • Ribasés M, Gratacos M, Armengol L et al. Met66 in the brainderived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type. Mol Psychiatry 2003; 8: 745-751.
    • (2003) Mol Psychiatry , vol.8 , pp. 745-751
    • Ribasés, M.1    Gratacos, M.2    Armengol, L.3
  • 30
    • 20244381139 scopus 로고    scopus 로고
    • Association of BDNF with restricting anorexia nervosa and minimum body mass index: A family-based association study of eight european populations
    • Ribasés M, Gratacos M, Fernández-Aranda F et al. Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations. Eur J Hum Genet 2005; 13: 428-434.
    • (2005) Eur J Hum Genet , vol.13 , pp. 428-434
    • Ribasés, M.1    Gratacos, M.2    Fernández-Aranda, F.3
  • 32
    • 58149163141 scopus 로고    scopus 로고
    • Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
    • Thorleifsson G, Walters GB, Gudbjartsson DF et al. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2009; 41: 18-24.
    • (2009) Nat Genet , vol.41 , pp. 18-24
    • Thorleifsson, G.1    Walters, G.B.2    Gudbjartsson, D.F.3
  • 33
    • 0035058585 scopus 로고    scopus 로고
    • Haplotypes vs single marker linkage disequilibrium tests what do we gain?
    • Akey J, Jin L, Xiong M. Haplotypes vs single marker linkage disequilibrium tests: what do we gain? Eur J Hum Genet 2001; 9: 291-300.
    • (2001) Eur J Hum Genet , vol.9 , pp. 291-300
    • Akey, J.1    Jin, L.2    Xiong, M.3
  • 34
    • 49449085611 scopus 로고    scopus 로고
    • Common SNPs in LEP and LEPR associated with birth weight and type 2 diabetes-related metabolic risk factors in twins
    • Souren NY, Paulussen AD, Steyls A et al. Common SNPs in LEP and LEPR associated with birth weight and type 2 diabetes-related metabolic risk factors in twins. Int J Obes 2008; 32: 1233-1239.
    • (2008) Int J Obes , vol.32 , pp. 1233-1239
    • Souren, N.Y.1    Paulussen, A.D.2    Steyls, A.3
  • 35
    • 0038207754 scopus 로고    scopus 로고
    • Genetic variation in the leptin receptor gene, leptin, and weight gain in young Dutch adults
    • van Rossum CT, Hoebee B, van Baak MA et al. Genetic variation in the leptin receptor gene, leptin, and weight gain in young Dutch adults. Obes Res 2003; 11: 377-386.
    • (2003) Obes Res , vol.11 , pp. 377-386
    • Van Rossum, C.T.1    Hoebee, B.2    Van Baak, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.