-
3
-
-
59849128464
-
Genetics of obesity in humans
-
Farooqi IS, O'Rahilly S. Genetics of obesity in humans. Endocr Rev 2006; 22: 221-226.
-
(2006)
Endocr Rev
, vol.22
, pp. 221-226
-
-
Farooqi, I.S.1
O'rahilly, S.2
-
5
-
-
3142731898
-
The critical role of the melanocortin system in the control of energy intake
-
Seeley RJ, Drazen DL, Clegg DJ. The critical role of the melanocortin system in the control of energy intake. Annu Rev Nutr 2004; 24: 133-149.
-
(2004)
Annu Rev Nutr
, vol.24
, pp. 133-149
-
-
Seeley, R.J.1
Drazen, D.L.2
Clegg, D.J.3
-
6
-
-
0037456768
-
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
-
Farooqi IS, Keogh JM, Yeo GSH et al. Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. N Engl J Med 2003; 348: 1085-1095.
-
(2003)
N Engl J Med
, vol.348
, pp. 1085-1095
-
-
Farooqi, I.S.1
Keogh, J.M.2
Yeo, G.S.H.3
-
7
-
-
33846409122
-
Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor
-
Farooqi IS, Wangensteen T, Collins S et al. Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor. N Engl J Med 2007; 356: 237-247.
-
(2007)
N Engl J Med
, vol.356
, pp. 237-247
-
-
Farooqi, I.S.1
Wangensteen, T.2
Collins, S.3
-
8
-
-
23444460111
-
Genetics of leptin and obesity: A HuGE review
-
Paracchini V, Pedotti P, Taioli E. Genetics of leptin and obesity: a HuGE review. Am J Epidemiol 2005; 162: 101-114.
-
(2005)
Am J Epidemiol
, vol.162
, pp. 101-114
-
-
Paracchini, V.1
Pedotti, P.2
Taioli, E.3
-
9
-
-
33847017334
-
Common genetic variations in CCK, leptin, and leptin receptor genes are associated with specific human eating patterns
-
De Krom M, van der Schouw YT, Hendriks J et al. Common genetic variations in CCK, leptin, and leptin receptor genes are associated with specific human eating patterns. Diabetes 2007; 56: 276-280.
-
(2007)
Diabetes
, vol.56
, pp. 276-280
-
-
De Krom, M.1
Van Der Schouw, Y.T.2
Hendriks, J.3
-
10
-
-
44349142294
-
Common variants near MC4R are associated with fat mass, weight and risk of obesity
-
Loos RJ, Lindgren CM, Li S et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008; 40: 768-775.
-
(2008)
Nat Genet
, vol.40
, pp. 768-775
-
-
Loos, R.J.1
Lindgren, C.M.2
Li, S.3
-
11
-
-
0038392755
-
Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor
-
Xu B, Goulding EH, Zang K et al. Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat Neurosci 2003; 6: 736-742.
-
(2003)
Nat Neurosci
, vol.6
, pp. 736-742
-
-
Xu, B.1
Goulding, E.H.2
Zang, K.3
-
12
-
-
50449091503
-
The power of the extreme in elucidating obesity
-
Froguel P, Blakemore AIF. The power of the extreme in elucidating obesity. N Engl J Med 2008; 359: 891-893.
-
(2008)
N Engl J Med
, vol.359
, pp. 891-893
-
-
Froguel, P.1
Blakemore, A.I.F.2
-
13
-
-
37549055474
-
Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity
-
Unger TJ, Calderon GA, Bradley LC et al. Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity. J Neurosci 2007; 27: 14265-14274.
-
(2007)
J Neurosci
, vol.27
, pp. 14265-14274
-
-
Unger, T.J.1
Calderon, G.A.2
Bradley, L.C.3
-
14
-
-
33845530762
-
Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene
-
Gray J, Yeo GS, Cox JJ et al. Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene. Diabetes 2006; 55: 3366-3371.
-
(2006)
Diabetes
, vol.55
, pp. 3366-3371
-
-
Gray, J.1
Yeo, G.S.2
Cox, J.J.3
-
15
-
-
7044262828
-
A de novo mutation affecting human TrkB associated with severe obesity and developmental delay
-
Yeo GS, Connie Hung CC, Rochford J et al. A de novo mutation affecting human TrkB associated with severe obesity and developmental delay. Nat Neurosci 2004; 7: 1187-1189.
-
(2004)
Nat Neurosci
, vol.7
, pp. 1187-1189
-
-
Yeo, G.S.1
Connie Hung, C.C.2
Rochford, J.3
-
16
-
-
50449091665
-
Brain-derived neurotrophic factor in the WAGR syndrome
-
Han JC, Liu QR, Jones MP et al. Brain-derived neurotrophic factor in the WAGR syndrome. N Engl J Med 2008; 359: 918-927.
-
(2008)
N Engl J Med
, vol.359
, pp. 918-927
-
-
Han, J.C.1
Liu, Q.R.2
Jones, M.P.3
-
17
-
-
17744403132
-
Obesity risk is associated with carbohydrate intake in women carrying the Gln27Glu beta2-adrenoceptor polymorphism
-
Martinez JA, Corbalán MS, Sánchez-Villegas A et al. Obesity risk is associated with carbohydrate intake in women carrying the Gln27Glu beta2-adrenoceptor polymorphism. J Nutr 2003; 133: 2549-2554.
-
(2003)
J Nutr
, vol.133
, pp. 2549-2554
-
-
Martinez, J.A.1
Corbalán, M.S.2
Sánchez-Villegas, A.3
-
18
-
-
0025720531
-
Human and rat brain-derived neurotrophic factor and neurotrophin-3: Gene structures, distributions, and chromosomal localizations
-
Maisonpierre PC, Le Beau MM, Espinosa R et al. Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations. Genomics 1991; 10: 558-568.
-
(1991)
Genomics
, vol.10
, pp. 558-568
-
-
Maisonpierre, P.C.1
Le Beau, M.M.2
Espinosa, R.3
-
19
-
-
47249097896
-
BDNF variability in opioid addicts and response to methadone treatment: Preliminary findings
-
De Cid R, Fonseca F, Gratacos M et al. BDNF variability in opioid addicts and response to methadone treatment: preliminary findings. Genes Brain Behav 2008; 7: 512-522.
-
(2008)
Genes Brain Behav
, vol.7
, pp. 512-522
-
-
De Cid, R.1
Fonseca, F.2
Gratacos, M.3
-
20
-
-
13444269543
-
Haploview: Analysis and visualization of LD and haplotype maps
-
Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-265.
-
(2005)
Bioinformatics
, vol.21
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
-
21
-
-
41649094148
-
Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data
-
Dudbridge F. Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Hum Hered 2008; 66: 87-98.
-
(2008)
Hum Hered
, vol.66
, pp. 87-98
-
-
Dudbridge, F.1
-
23
-
-
34247855844
-
A novel mutation Thr162Arg of the melanocortin 4 receptor gene in a Spanish children and adolescent population
-
Ochoa MC, Azcona C, Biebermann H et al. A novel mutation Thr162Arg of the melanocortin 4 receptor gene in a Spanish children and adolescent population. Clin Endocrinol 2007; 66: 652-658.
-
(2007)
Clin Endocrinol
, vol.66
, pp. 652-658
-
-
Ochoa, M.C.1
Azcona, C.2
Biebermann, H.3
-
24
-
-
50449099144
-
Lessons from extreme human obesity: Monogenic disorders
-
Ranadive SA, Vaisse C. Lessons from extreme human obesity: monogenic disorders. Endocrinol Metab Clin North Am 2008; 37: 733-751.
-
(2008)
Endocrinol Metab Clin North Am
, vol.37
, pp. 733-751
-
-
Ranadive, S.A.1
Vaisse, C.2
-
25
-
-
18344396039
-
A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference
-
Heo M, Leibel RL, Fontaine KR et al. A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference. Int J Obes 2002; 26: 640-646.
-
(2002)
Int J Obes
, vol.26
, pp. 640-646
-
-
Heo, M.1
Leibel, R.L.2
Fontaine, K.R.3
-
26
-
-
19944429689
-
Mutation screen of the brain derived neurotrophic factor gene (BDNF): Identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder
-
Friedel S, Horro FF, Wermter AK et al. Mutation screen of the brain derived neurotrophic factor gene (BDNF): identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet 2005; 5: 96-99.
-
(2005)
Am J Med Genet B Neuropsychiatr Genet
, vol.5
, pp. 96-99
-
-
Friedel, S.1
Horro, F.F.2
Wermter, A.K.3
-
27
-
-
51849117596
-
Association of the BDNF Val66Met variation with obesity in women
-
Beckers S, Peeters A, Zegers D et al. Association of the BDNF Val66Met variation with obesity in women. Mol Genet Metab 2008; 95: 110-112.
-
(2008)
Mol Genet Metab
, vol.95
, pp. 110-112
-
-
Beckers, S.1
Peeters, A.2
Zegers, D.3
-
28
-
-
33744958340
-
BDNF Val66Met polymorphism is associated with body mass index in healthy adults
-
Gunstad J, Schofield P, Paul RH et al. BDNF Val66Met polymorphism is associated with body mass index in healthy adults. Neuropsychobiology 2006; 53: 153-156.
-
(2006)
Neuropsychobiology
, vol.53
, pp. 153-156
-
-
Gunstad, J.1
Schofield, P.2
Paul, R.H.3
-
29
-
-
10744223605
-
Met66 in the brainderived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type
-
Ribasés M, Gratacos M, Armengol L et al. Met66 in the brainderived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type. Mol Psychiatry 2003; 8: 745-751.
-
(2003)
Mol Psychiatry
, vol.8
, pp. 745-751
-
-
Ribasés, M.1
Gratacos, M.2
Armengol, L.3
-
30
-
-
20244381139
-
Association of BDNF with restricting anorexia nervosa and minimum body mass index: A family-based association study of eight european populations
-
Ribasés M, Gratacos M, Fernández-Aranda F et al. Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations. Eur J Hum Genet 2005; 13: 428-434.
-
(2005)
Eur J Hum Genet
, vol.13
, pp. 428-434
-
-
Ribasés, M.1
Gratacos, M.2
Fernández-Aranda, F.3
-
32
-
-
58149163141
-
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
-
Thorleifsson G, Walters GB, Gudbjartsson DF et al. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2009; 41: 18-24.
-
(2009)
Nat Genet
, vol.41
, pp. 18-24
-
-
Thorleifsson, G.1
Walters, G.B.2
Gudbjartsson, D.F.3
-
33
-
-
0035058585
-
Haplotypes vs single marker linkage disequilibrium tests what do we gain?
-
Akey J, Jin L, Xiong M. Haplotypes vs single marker linkage disequilibrium tests: what do we gain? Eur J Hum Genet 2001; 9: 291-300.
-
(2001)
Eur J Hum Genet
, vol.9
, pp. 291-300
-
-
Akey, J.1
Jin, L.2
Xiong, M.3
-
34
-
-
49449085611
-
Common SNPs in LEP and LEPR associated with birth weight and type 2 diabetes-related metabolic risk factors in twins
-
Souren NY, Paulussen AD, Steyls A et al. Common SNPs in LEP and LEPR associated with birth weight and type 2 diabetes-related metabolic risk factors in twins. Int J Obes 2008; 32: 1233-1239.
-
(2008)
Int J Obes
, vol.32
, pp. 1233-1239
-
-
Souren, N.Y.1
Paulussen, A.D.2
Steyls, A.3
-
35
-
-
0038207754
-
Genetic variation in the leptin receptor gene, leptin, and weight gain in young Dutch adults
-
van Rossum CT, Hoebee B, van Baak MA et al. Genetic variation in the leptin receptor gene, leptin, and weight gain in young Dutch adults. Obes Res 2003; 11: 377-386.
-
(2003)
Obes Res
, vol.11
, pp. 377-386
-
-
Van Rossum, C.T.1
Hoebee, B.2
Van Baak, M.A.3
|