Monoclonal anti-vascular endothelial growth factor antibody reduces fluid volume in an experimental model of inflammatory pleural effusion

Respirology

Volumn 14, Issue 8, 2009, Pages 1188-1193

  Ribeiro, Sabrina C C ^a   Vargas, Francisco S ^a   Antonangelo, Leila ^a   Marchi, Evaldo ^a   Genofre, Eduardo H ^a   Acencio, Milena M P ^a   Teixeira, Lisete R ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Bevacizumab; Cytokines; Effusion; Inflammation; Nitrate; Pleural; Silver; Talc

Indexed keywords

BEVACIZUMAB; EVANS BLUE; INTERLEUKIN 8; SILVER NITRATE; TALC; VASCULOTROPIN ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; NONHUMAN; PLEURA EFFUSION; PLEURA FLUID; PLEURODESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTIBODIES, MONOCLONAL; CAPILLARY PERMEABILITY; DISEASE MODELS, ANIMAL; INTERLEUKIN-8; PLEURAL EFFUSION; PLEURODESIS; RABBITS; SILVER NITRATE; TALC; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 70350435581     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/j.1440-1843.2009.01628.x     Document Type: Article

References (29)

1. Light RW, Vargas FS. Pleural sclerosis for the treatment of pneumothorax and pleural effusion. Lung 1997 175 : 213 223.
2. Lee YC, Yasay JR, Johnson JE, Parker RE, Thompson PJ et al. Comparing transforming growth factor β-2, talc and bleomycin as pleurodesing agents in sheep. Respirology 2002 3 : 209 216.
3. Vargas FS, Teixeira LR, Silva LM, Carmo AO, Light RW. Comparison of silver nitrate and tetracycline as pleural sclerosing agents in rabbits. Chest 1995 108 : 1080 1083.
4. Lee YC, Baumann MH, Maskell NA, Waterer GW, Eaton TE et al. Pleurodesis practice for malignant pleural effusions in five english-speaking countries. Chest 2003 124 : 2229 2238.
5. Paschoalini MS, Vargas FS, Marchi E, Pereira JR, Jatene FB et al. Prospective randomized trial of silver nitrate vs talc slurry in pleurodesis for symptomatic pleural effusions. Chest 2005 128 : 684 689.
6. Marchi E, Vargas FS, Acencio MM, Antonangelo L, Teixeira LR et al. Talc and silver nitrate induce systemic inflammatory effects in the acute phase of experimental pleurodesis in rabbits. Chest 2004 125 : 2268 2277.
7. Marchi E, Vargas FS, Teixeira LR, Acencio MM, Antonangelo L et al. Intrapleural low-dose silver nitrate elicits more pleural inflammation and less systemic inflammation than low-dose talc. Chest 2005 128 : 1798 1804.
8. Senger DR, Galli SJ, Dvorak AM, Peruzzi CA, Harvey VS et al. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 1983 219 : 983 985.
9. Breier G, Albrecht U, Sterrer S, Risau W. Expression of vascular endothelial growth factor during angiogenesis and endothelial cell differentiation. Development 1992 114 : 521 532.
10. Ferrara N. Molecular and biological properties of vascular endothelial growth factor. J. Mol. Med. 1999 77 : 527 543. (Pubitemid 29426311)
11. Cheng DS, Rodriguez RM, Perkett EA, Rogers J, Bienvenu G et al. Vascular endothelial growth factor in pleural fluid. Chest 1999 116 : 760 765.
12. Lee YC, Melkerneker D, Thompson PJ, Light RW, Lane KB. Transforming growth factor βinduces vascular endothelial growth factor elaboration from pleural mesothelial cells in vivo and in vitro. Am. J. Respir. Crit. Care Med. 2002 165 : 88 94.
13. Vargas FS, Teixeira LR, Vaz MA, Carmo AO, Marchi E et al. Silver nitrate is superior to talc slurry in producing pleurodesis in rabbits. Chest 2000 118 : 808 813.
14. Teixeira LR, Vargas FS, Acencio MM, Bumlai RU, Antonangelo L et al. Experimental pleurodesis induced by antibiotics (macrolides or quinolones). Clinics (Sao Paulo) 2006 61 : 559 564.
15. Teixeira LR, Wu W, Cheng DS, Light RW. The effect of corticosteroids on pleurodesis induced by doxycycline in rabbits. Chest 2002 121 : 216 219.
16. Papaioannou AI, Kostikas K, Kollia P, Gourgoulianis KI. Clinical implications for vascular endothelial growth factor in the lung: friend or foe? Respir. Res. 2006 7 : 128.
17. Sack U, Hoffmann M, Zhao XJ, Chan KS, Hui DS et al. Vascular endothelial growth factor in pleural effusions of different origin. Eur. Respir. J. 2005 25 : 600 604.
18. Ferrara N. VEGF: an update on biological and therapeutic aspects. Curr. Opin. Biotechnol. 2000 11 : 617 624.
19. Hamed EA, El-Noewihi AM, Mohamed AZ. Vasoactive mediators (VEGF and TNF-α) in patients with malignant and tuberculous pleural effusions. Respirology 2004 9 : 81 6.
20. Yano S, Herbst RS, Shinohara H, Knigton B, Bucana CD et al. Treatment for malignant pleural effusion of human lung adenocarcinoma by inhibition of vascular endothelial growth factor tyrosine kinase phosphorylation. Clin. Cancer Res. 2000 6 : 957 965.
21. Mesiano S, Ferrara N, Jaffe RB. Role of vascular endothelial growth factor in ovarian cancer: inhibition of ascites formation by immunoneutralization. Am. J. Pathol. 1998 153 : 1249 1256.
22. Chung CL, Yeh CY, Sheu JR, Chen YC, Chang SC. Repeated thoracenteses affect proinflammatory cytokines, vascular endothelial growth factor and fibrinolytic activity in pleural transudates. Am. J. Med. Sci. 2007 334 : 452 457.
23. Ferrara N, Hillan KJ, Gerber HP, Novotny W. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat. Rev. Drug Discov. 2004 3 : 391 400.
24. Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J et al. Bevacizumab plus irinotecan, fluorouracil and leucovorin for metastatic colorectal cancer. N. Engl. J. Med. 2004 350 : 2335 2342.
25. Giantonio BJ, Catalano PJ, Meropol NJ, O'Dwyer PJ, Mitchell EP et al. High-dose bevacizumab improves survival when combined with FOLFOX in previously treated advanced colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J. Clin. Oncol. 2007 25 : 1539 1544.
26. Pichelmayer O, Zielinsk C, Raderer M. Response of a nonmalignant pleural effusion to bevacizumab. N. Engl. J. Med. 2005 353 : 740 741.
27. Stathopoulos GT, Psallidas I, Moustaki A, Moschos C, Kollintza A et al. A central role for tumor-derived monocyte chemoattractant protein-1 in malignant pleural effusion. J. Natl. Cancer Inst. 2008 100 : 1464 1476.
28. Guo YB, Kalomenidis I, Hawthorne M, Parman KS, Lane KB et al. Pleurodesis is inhibited by vascular endothelial growth factor antibody. Chest 2005 128 : 1790 1797.
29. Guo YB, Xie CM, Light RW. Effect of anti-vascular endothelial growth factor on pleurodesis induced by transforming growth factor-beta or doxycycline in rabbits. Zhonghua Jie He He Hu Xi Za Zhi 2006 29 : 39 43.