Prothrombotic and inflammatory effects of intravenous administration of human immunoglobulin G in dogs

Journal of Veterinary Internal Medicine

Volumn 23, Issue 6, 2009, Pages 1164-1169

  Tsuchiya, R ^a   Akutsu, Y ^a   Ikegami, A ^a   Scott, M A ^b   Neo, S ^a   Ishikawa, T ^a   Hisasue, M ^a   Yamada, T ^a  

^a AZABU UNIVERSITY   (Japan)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Adverse effect; Coagulation; Hypercoagulability; Immunoglobulin

Indexed keywords

IMMUNOGLOBULIN G; PLASMA PROTEIN;

ANIMAL; ANIMAL DISEASE; ARTICLE; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOG; DOG DISEASE; FEMALE; HUMAN; INFLAMMATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; THROMBOCYTE COUNT; THROMBOSIS;

ANIMALS; BLOOD PROTEINS; DOG DISEASES; DOGS; FEMALE; HUMANS; IMMUNOGLOBULIN G; INFLAMMATION; INJECTIONS, INTRAVENOUS; MALE; PLATELET COUNT; THROMBOSIS;

ANIMALIA; CANIS FAMILIARIS;

EID: 70350393625     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1939-1676.2009.0402.x     Document Type: Article

References (31)

1. Knezevic-Maramica I, Kruskall MS. Intravenous immune globulins: An update for clinicians. Transfusion 2003;43:1460-1480.
2. Bianco D, Armstrong PJ, Washabau RJ. Treatment of severe immune-mediated thrombocytopenia with human IV immunoglobulin in 5 dogs. J Vet Intern Med 2007;21:694-699.
3. Foster AP. Immunomodulation and immunodeficiency. Vet Dermatol 2004;15:115-126.
4. Rahilly LJ, Keating JH, O'Toole TE. The use of intravenous human immunoglobulin in treatment of severe pemphigus foliaceus in a dog. J Vet Intern Med 2006;20:1483-1486.
5. Scott-Moncrieff JC, Reagan WJ, Glickman LT, et al. Treatment of nonregenerative anemia with human gamma-globulin in dogs. J Am Vet Med Assoc 1995;206:1895-1900.
6. Scott-Moncrieff JC, Reagan WJ. Human intravenous immunoglobulin therapy. Semin Vet Med Surg (Small Anim) 1997;12:178-185.
7. Scott-Moncrieff JC, Reagan WJ, Snyder PW, et al. Intravenous administration of human immune globulin in dogs with immunemediated hemolytic anemia. J Am Vet Med Assoc 1997;210:1623-1627.
8. Kellerman DL, Bruyette DS. Intravenous human immunoglobulin for the treatment of immune-mediated hemolytic anemia in 13 dogs. J Vet Intern Med 1997;11:327-332.
9. Katz U, Shoenfeld Y. Intravenous immunoglobulin therapy and thromboembolic complications. Lupus 2005;14:802-808.
10. Vucic S, Siao P, Chong T, et al. Thromboembolic complications of intravenous immunoglobulin treatment. Eur Neurol 2004;52:141-144.
11. Carr AP, Panciera DL, Kidd LJ. Prognostic factors for mortality and thromboembolism in canine immune-mediated hemolytic anemia: A retrospective study of 72 dogs. J Vet Intern Med 2002;16:504-509.
12. Scott-Moncrieff JC, Treadwell NG, McCullough SM, et al. Hemostatic abnormalities in dogs with primary immune-mediated hemolytic anemia. J Am Anim Hosp Assoc 2001;37:220-227.
13. Mitchell KD, Kruth SA, Wood RD, et al. Serum acute phase protein concentrations in dogs with autoimmune hemolytic anemia. J Vet Intern Med 2009;23:585-591.
14. Baba R, Shibata A, Tsurusawa M. Single high-dose intravenous immunoglobulin therapy for Kawasaki disease increases plasma viscosity. Circ J 2005;69:962-964.
15. Steinberger BA, Ford SM, Coleman TA. Intravenous immuno-globulin therapy results in post-infusional hyperproteinemia, increased serum viscosity, and pseudohyponatremia. Am J Hematol 2003;73:97-100.
16. Mohri M, Shakeri H, Zadeh SL. Effects of common anticoagulants (heparin, citrate and EDTA) on routine plasma biochem-istry of cattle. Comp Clin Pathol 2007;16:207-209.
17. Stokol T, Brooks M, Erb H, et al. Evaluation of kits for the detection of fibrin(ogen) degradation products in dogs. J Vet Intern Med 1999;13:478-484.
18. Wolling H, Mischke R. Examination of the cross-reactivity and sensitivity of a commercial FDP latex agglutination test towards purified canine fibrin(ogen) degradation products. Klein-tierpraxis 1995;40:23-32 (in German with English abstract).
19. Maruyama H, Miura T, Sakai M, et al. The incidence of disseminated intravascular coagulation in dogs with malignant tumor. J Vet Med Sci 2004;66:573-575.
20. Ravanat C, Freund M, Dol F, et al. Cross-reactivity of human molecular markers for detection of prethrombotic states in various animal species. Blood Coagul Fibrinolysis 1995;6: 446-455.
21. Onishi T, Inokuma H, Ohno K, et al. C reactive protein concentration in normal and diseased dogs measured by laser nephelometric immunoassay. J Jpn Vet Med Assoc 2000;53:595-601 (in Japanese with English summary).
22. Rajagopalan S, Pizzo SV. Characterization of murine peritoneal macrophage receptors for fibrin(ogen) degradation products. Blood 1986;67:1224-1228.
23. Takeya H, Hamada T, Kume M, et al. Receptor-mediated endocytosis of thrombin-antithrombin III complex by the human monocytoid cell line U937. Biochem Biophys Res Commun 1994;200:1334-1340.
24. Reinhart WH, Berchtold PE. Effect of high-dose intravenous immunoglobulin therapy on blood rheology. Lancet 1992;339: 662-664.
25. Marie I, Maurey G, Herve F, et al. Intravenous immuno-globulin-associated arterial and venous thrombosis; report of a series and review of the literature. Br J Dermatol 2006;155: 714-721.
26. Tam DA, Morton LD, Stroncek DF, Leshner RT. Neutropenia in a patient receiving intravenous immune globulin. J Neuroimmunol 1996;64:175-178.
27. Berkovitch M, Dolinski G, Tauber T, et al. Neutropenia as a complication of intravenous immunoglobulin (IVIg) therapy in chil-dren with immune thrombocytopenic purpura: Common and non-alarming. Int J Immunopharmaco 1999;21:411-415.
28. Jarius S, Eichhorn P, Albert MH, et al. Intravenous immunoglobulins contain naturally occurring antibodies that mimic antineutrophil cytoplasmic antibodies and activate neutrophils in a TNF alpha-dependent and Fc-receptor-independent way. Blood 2007;109:4376-4382.
29. Huisse MG, Pease S, Hurtado-Nedelec M, et al. Leukocyte activation: The link between inflammation and coagulation during heatstroke. Crit Care Med 2008;36:2288-2295.
30. Reagan WJ, Scott-Moncrieff C, Christian J, et al. Effects of human intravenous immunoglobulin on canine monocytes and lym-phocytes. Am J Vet Res 1998;59:1568-1574.
31. Miller E. Diagnosis and treatment of immune-mediated hemolytic anemia. In: Bonagura JD, ed. Current Veterinary Therapy XIII. Philadelphia, PA: WB Saunders; 2000:427-434.