Long-term oral polyamine intake increases blood polyamine concentrations

Journal of Nutritional Science and Vitaminology

Volumn 55, Issue 4, 2009, Pages 361-366

  Soda, Kuniyasu ^a   Kano, Yoshihiko ^a   Sakuragi, Masako ^a   Takao, Koichi ^b   Lefor, Alan ^a   Konishi, Fumio ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b JOSAI UNIVERSITY   (Japan)

Author keywords

Food; Human; Mice; Polyamine; Spermine

Indexed keywords

POLYAMINE; SPERMIDINE; SPERMINE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD LEVEL; BLOOD POLYAMINE CONCENTRATION; CONTROLLED STUDY; FERMENTED PRODUCT; FOOD INTAKE; HUMAN; HUMAN EXPERIMENT; LONG TERM EXPOSURE; MALE; MORTALITY; MOUSE; NONHUMAN; NORMAL HUMAN; POLYAMINE SYNTHESIS; SOYBEAN;

ADULT; AGED; AGING; ANIMALS; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MALE; MICE; MICE, INBRED ICR; MIDDLE AGED; PLANT PREPARATIONS; POLYAMINES; SOY FOODS; SOYBEANS; SPERMINE;

GLYCINE MAX; MUS;

EID: 70350383102     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.55.361     Document Type: Article

References (19)

1. Slotkin TA, Seidler FJ, Trepanier PA, Whitmore WL, Lerea L, Barnes GA, Weigel SJ, Bartolome J. 1982. Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase. J Pharmacol Exp Ther 222: 741-745.
2. Luk GD, Baylin SB. 1984. Inhibition of intestinal epithelial DNA synthesis and adaptive hyperplasia after jejunectomy in the rat by suppression of polyamine biosynthesis. J Clin Invest 74: 698-704.
3. Bardócz S, Grant G, Brown DS, Ralph A, Pusztai A. 1993. Polyamines in food - implications for growth and health. J Nutr Biochem 4: 66-71. (Pubitemid 23178319)
4. Soda K, Kano Y, Nakamura T, Kasono K, Kawakami M, Konishi F. 2005. Spermine, a natural polyamine, suppresses LFA-1 expression on human lymphocyte. J Immunol 175: 237-245. (Pubitemid 40884324)
5. Kano Y, Soda K, Nakamura T, Saitoh M, Kawakami M, Konishi F. 2007. Increased blood spermine levels decrease the cytotoxic activity of lymphokine-activated killer cells: a novel mechanism of cancer evasion. Cancer Immunol Immunother 56: 771-781. (Pubitemid 46723577)
6. Nishimura K, Araki N, Ohnishi Y, Kozaki S. 2001. Effects of dietary polyamine deficiency on Trypanosoma gambiense infection in rats. Exp Parasitol 97: 95-101. (Pubitemid 32980605)
7. Bardócz S, Duguid TJ, Brown DS, Grant G, Pusztai A, White A, Ralph A. 1995. The importance of dietary polyamines in cell regeneration and growth. Br J Nutr 73: 819-828.
8. Uda K, Tsujikawa T, Fujiyama Y, Bamba T. 2003. Rapid absorption of luminal polyamines in a rat small intestine ex vivo model. J Gastroenterol Hepatol 18: 554-559. (Pubitemid 36645290)
9. Kobayashi M, Xu YJ, Samejima K, Goda H, Niitsu M, Takahashi M, Hashimoto Y. 2003. Fate of orally administered 15N-labeled polyamines in rats bearing solid tumors. Biol Pharm Bull 26: 285-288. (Pubitemid 39663610)
10. Cipolla B, Guilli F, Moulinoux JP. 2003. Polyamine-reduced diet in metastatic hormone-refractory prostate cancer (HRPC) patients. Biochem Soc Trans 31: 384-387. (Pubitemid 36520682)
11. Brodal BP, Eliassen KA, Ronning H, Osmundsen H. 1999. Effects of dietary polyamines and clofibrate on metabolism of polyamines in the rat. J Nutr Biochem 10: 700-708.
12. Okamoto A, Sugi E, Koizumi Y, Yanagida F, Udaka S. 1997. Polyamine content of ordinary foodstuffs and various fermented foods. Biosci Biotechnol Biochem 61: 1582-1584.
13. Nishimura K, Shiina R, Kashiwagi K, Igarashi K. 2006. Decrease in polyamines with aging and their ingestion from food and drink. J Biochem 139: 81-90. (Pubitemid 43258849)
14. Til HP, Falke HE, Prinsen MK, Willems MI. 1997. Acute and subacute toxicity of tyramine, spermidine, spermine, putrescine and cadaverine in rats. Food Chem Toxicol 35: 337-348.
15. Weiss TS, Bernhardt G, Buschauer A, Thasler WE, Dolgner D, Zirngibl H, Jauch KW. 2002. Polyamine levels of human colorectal adenocarcinomas are correlated with tumor stage and grade. Int J Colorectal Dis 17: 381-387. (Pubitemid 36075786)
16. Nishiguchi S, Tamori A, Koh N, Fujimoto S, Takeda T, Shiomi S, Oka H, Yano Y, Otani S, Kuroki T. 2002. Erythrocyte-binding polyamine as a tumor growth marker for human hepatocellular carcinoma. Hepatogastroenterology 49: 504-507. (Pubitemid 34606583)
17. Sousadias MG, Smith TK. 1995. Toxicity and growth-promoting potential of spermine when fed to chicks. J Anim Sci 73: 2375-2381.
18. Dorhout B, van Faassen A, van Beusekom CM, Kingma AW, de Hoog E, Nagel GT, Karrenbeld A, Boersma ER, Muskiet FA. 1997. Oral administration of deuterium-labelled polyamines to sucking rat pups: luminal uptake, metabolic fate and effects on gastrointestinal maturation. Br J Nutr 78: 639-654. (Pubitemid 27437815)
19. Deloyer P, Peulen O, Dandrifosse G. 2001. Dietary polyamines and non-neoplastic growth and disease. Eur J Gastroenterol Hepatol 13: 1027-1032. (Pubitemid 32905193)