Antitumor activity of the lipid fraction of the spores of an anaerobic bacterium Clostridium butyricum

Microbiology

Volumn 78, Issue 5, 2009, Pages 580-584

  Gaenko, G P ^a   Moiseeva, E V ^a   Savel'ev, O Yu ^b   Molotkovskii, Yu G ^a   Vodovozova, E L ^a  

^a SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

Antitumor activity; Lipid fraction of bacterial spores; Resorcinolic lipids

Indexed keywords

BACTERIA (MICROORGANISMS); CLOSTRIDIUM BUTYRICUM;

EID: 70350356854     PISSN: 00262617     EISSN: None     Source Type: Journal    
DOI: 10.1134/S0026261709050087     Document Type: Article

References (21)

1. Su, Ch.-J., Reusch, R.N., and Sadoff, H.L., Isolation and Characterization of Unique Lipids from Azotobacter vinelandii Cysts, J. Bacteriol., 1981, vol. 141, pp. 80-90.
2. Reusch, R. and Sadoff, H., Novel Lipid Components of the Azotobacter vinelandii Cyst Membrane, Nature, 1983, vol. 302, pp. 268-271.
3. Kozubek, A. and Tyman, H.P.J., Resorcinolic Lipids, the Natural Non-Isoprenoid Phenolic Amphiphiles and Their Biological Activity, Chem. Rev., 1999, no. 1, pp. 1-25.
4. Kozubek, A., Zamowski, R., Stasiuk, M., and Gubemator, J., Natural Amphiphilic Phenols as Bioactive Compounds, Cell. Mol. Biol. Lett., Vol. 6. 2A, 2001, pp. 361-365.
5. Batrakov, S.G., Pridachina, N.N., Kruglyak, E.D., and Novogrudskaya, E.D., Phenolic Lipid from Azotobacter chroococcum Cysts, Khim. Prir. Soedin., 1977, no. 4, pp. 494-499.
6. 1 Autoregulatory Factor, Mikrobiologiya, 1985, vol. 54, no. 2, pp. 186-189.
7. Funa, N., Ozava, H., Hirata, A., and Horinouchi, S., Phenolic Lipid Synthesis by Type III Polyketide Synthases is Essential for Cyst Formation in Azotobacter vinelandii, Proc. Natl. Acad. Sci. USA, 2006, vol. 103, pp. 6356-6361.
8. Zamowska, E.D., Zamowski, R., and Kozubek, A., Alkylresorzinols in Fruit Pulp and Leaves of Gingo biloba L., Z. Naturforsch, 2000, vol. 55, pp. 881-885.
9. Duda, V.I., Gaenko, G.P., and Kalunyants, K.A., Radioprotective Effect of Extracts from the Spores of Anaerobic Bacteria at Irradiation Damage to Animals, Radiobiologiya, 1980, vol. 20, no. 6, pp. 926-929.
10. Gaenko, G.P., Duda, V.I., Koronelli, T.V., and Pakhlavuni, I.K., Biological Activity of the Polar Lipid from Clostridium butyricum Spores, Mikrobiologiya, 1986, vol. 55, no. 5, pp. 804-807.
11. Duda, V.I., Kalunyants, K.A., Gaenko, G.P., Malkova, I.V., and Kryukova, A.I., Radioprotective Effect of Spores of Some Anaerobic Bacteria in Irradiation Damage to Animals, Radiobiologiya, 1980, vol. 20, no. 6, pp. 929-932.
12. Gaenko, G.P., Disruption of Spores of Anaerobic Clostridia, Mikrobiol. Prom-st., 1978, vol 12, p. 6.
13. Keits, M., Techniques of Lipidology: Isolation, Analysis, and Identification of Lipids, Amsterdam: Elsevier, 1972 [Russ. Transl. Moscow: Mir, 1975].
14. Bligh, E. and Dayer, W., A Rapid Method of Total Lipid Extraction and Purification, Can, J. Phys., 1959, vol. 37, pp. 911-917.
15. Kozubek, A. and Tyman, J.H., Cereal Grain Resorcinolic Lipids: Mono and Dienoic Homologues Are Present in Rye Grains, Chem. Phys. Lipids, 1995, vol. 78, pp. 29-35.
16. Tepkeeva, I.I., Moiseeva, E.V., Chaadaeva, A.V., Zhavoronkova, E.V., Kessler, Yu.V., Semushkina, S.G., and Demushkin, V.P., Assessment of the Antitumor Activity of the Peptide Extracts of Medicinal Plants in a Transplantable Breast Cancer Model on Mice of the Line CBRB-Rb(8/17)1 lem, Byul. Eksperimental'noi Biologii I Meditsiny, 2008, vol. 145, no. 4, pp. 446-448.
17. Vodovozova, E.L., Moiseeva, E.V., Grechco, G.K., Gaenko, G.P., Nifantjev, N.E., Bovin, N.V., and Molotkovsky, J.G., Antitumour Activity of Liposomes, Equipped with Selectin Ligand SiaLeX, in Mouse Mammary Adenocarcinoma, Eur. J. Cancer, 2000, vol. 36, pp. 942-949.
18. Torrey, J.C. and Kahn, M.C., The Treatment of Flexner-Jobling Rat Carcinomas with Bacterial Proteolytic Ferments, J. Cancer Res., 1927, vol. 11, pp. 334-376.
19. Barbe, S., van Mellaert, L., and Anne, J., The Use of Clostridium Spores for Cancer Treatment, J. Appl. Microbiol., 2006, vol. 101, pp. 571-578.
20. Moiseeva, E.V., Merkulova, I.B., Bijleveld, C., Koten, J.W., Miroshnikov, A.I., and Den Otter, W., Therapeutic Effect of a Single Peritumoural Dose of IL-2 on Transplanted Murine Breast Cancer, Cancer. Immunol. Immunother, 2003, vol. 52, pp. 487-496.
21. Rejman, J. and Kozubek, A., Inhibitory Effect of Natural Phenolic Lipids upon NAD-Dependent Dehydrogenases and on Triglyceride Accumulation in 3T3-L1 Cells in Culture, J. Agric. Food Chem., 2004, vol. 52, no. 2, pp. 246-250.