Inducible expression of human angiostatin by AOXI promoter in P. pastoris using high-density cell culture

Molecular Biology Reports

Volumn 36, Issue 8, 2009, Pages 2265-2270

  Zhang, Ai Lian ^a   Zhang, Tian Yuan ^b   Luo, Jin Xian ^b   Fu, Ce Yi ^c   Qu, Zhi ^a   Yi, Guo Hui ^a   Su, Dong Xiao ^a   Tu, Fa Zhi ^a   Pan, Ying Wen ^a  

^a INSTITUTE OF TROPICAL BIOSCIENCE AND BIOTECHNOLOGY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c Hainan Provincial Institute for Drug Control   (China)

Author keywords

Angiostatin; High density cell culture; Inducible expression; P. pastoris

Indexed keywords

ALCOHOL OXIDASE; ALCOHOL OXIDASE 1; ANGIOSTATIN; GLYCEROL; OXYGEN; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; BIOMASS FERMENTATION; CELL CULTURE; CELL DENSITY; CHORIOALLANTOIS; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; DRUG PURIFICATION; IMMUNOREACTIVITY; LUNG CARCINOMA; MALE; MELANOMA; MOUSE; NONHUMAN; PH MEASUREMENT; PICHIA PASTORIS;

ALCOHOL OXIDOREDUCTASES; ANGIOGENESIS INHIBITORS; ANGIOSTATINS; ANIMALS; BIOREACTORS; BLOTTING, WESTERN; CARCINOMA, LEWIS LUNG; CELL COUNT; CELL GROWTH PROCESSES; CHICK EMBRYO; CHORIOALLANTOIC MEMBRANE; FERMENTATION; HUMANS; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; PICHIA; PROMOTER REGIONS, GENETIC; RECOMBINANT PROTEINS;

MUS;

EID: 70350346563     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-008-9443-9     Document Type: Article

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