Involvement of CHOP, an ER-stress apoptotic mediator, in both human sporadic ALS and ALS model mice

Neurobiology of Disease

Volumn 36, Issue 3, 2009, Pages 470-476

  Ito, Yasushi ^a   Yamada, Mitsunori ^b,c   Tanaka, Hirotaka ^a   Aida, Kazunari ^a   Tsuruma, Kazuhiro ^a   Shimazawa, Masamitsu ^a   Hozumi, Isao ^d   Inuzuka, Takashi ^d   Takahashi, Hitoshi ^c   Hara, Hideaki ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b National Saigata Medical Center   (Japan)

^c NIIGATA UNIVERSITY   (Japan)

^d GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Amyotrophic lateral sclerosis (ALS); Astrocyte; C EBP homologous protein (CHOP); Endoplasmic reticulum (ER) stress; Spinal cord; Superoxide dismutase 1 (SOD1)

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN HOMOLOGOUS PROTEIN; CELL PROTEIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GLIA CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MICROGLIA; MOTONEURON; MOUSE; NONHUMAN; OLIGODENDROGLIA; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SPINAL CORD; TRANSGENIC MOUSE;

AGED; AGED, 80 AND OVER; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ASTROCYTES; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MALE; MICE; MICE, TRANSGENIC; MICROGLIA; MIDDLE AGED; MOTOR NEURONS; NEUROGLIA; OLIGODENDROGLIA; SPINAL CORD; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR CHOP;

EID: 70350340050     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2009.08.013     Document Type: Article

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