Recurrent episodes of serotonin-reuptake inhibitor-mediated hyponatremia in an elderly patient

Consultant Pharmacist

Volumn 24, Issue 10, 2009, Pages 765-768

  Stovall, Rebecca ^a   Brahm, Nancy C ^b   Crosby, Kimberly M ^b  

^a INDIAN HEALTH SERVICE   (United States)

^b UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

Duloxetine; Elderly; Hyponatremia; SIADH; Syndrome of inappropriate antidiuretic hormone

Indexed keywords

ANTIDEPRESSANT AGENT; DULOXETINE; ESCITALOPRAM; NORADRENALIN; SODIUM; VASOPRESSIN;

AGED; AMNESIA; ARTICLE; CASE REPORT; DEPRESSION; DRUG DOSE TITRATION; DRUG WITHDRAWAL; FEMALE; HUMAN; HYPONATREMIA; INAPPROPRIATE VASOPRESSIN SECRETION; LETHARGY; MENTAL HEALTH; MUSCLE WEAKNESS; NAUSEA; NORADRENALIN UPTAKE; PERSONALITY DISORDER; RECURRENT DISEASE; SODIUM BLOOD LEVEL;

AGED; ANTIDEPRESSIVE AGENTS; DEPRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INAPPROPRIATE ADH SYNDROME; RECURRENCE; SEROTONIN UPTAKE INHIBITORS; SODIUM; THIOPHENES;

EID: 70350335762     PISSN: 08885109     EISSN: None     Source Type: Journal    
DOI: 10.4140/TCP.n.2009.765     Document Type: Article

References (20)

1. Kirby D, Ames D. Hyponatraemia and selective serotonin re-uptake inhibitors in elderly patients. Int J Geriatr Psychiatry 2001;16:484-493 (Pubitemid 32492382)
2. Nirmalani A, Stock SL, Catalano G. Syndrome of inappropriate antidiuretic hormone associated with escitalopram therapy. CNS Spectr 2006;11:429-432 (Pubitemid 43938811)
3. Fisher A, Davis M, Croft-Baker J et al. Citalopram-induced severe hyponatraemia with coma and seizure. Case report with literature and spontaneous reports review. Adverse Drug React Toxicol Rev 2002;21:179-187
4. Romero S, Pintor L, Serra M et al. Syndrome of inappropriate secretion of antidiuretic hormone due to citalopram and venlafaxine. Gen Hosp Psychiatry 2007;29:81-84 (Pubitemid 44960489)
5. Kruger S, Lindstaedt M. Duloxetine and hyponatraemia: a report of 5 cases. J Clin Psychopharmacol 2007;27:101-104
6. Maramatton BV. Duloxetine-induced syndrome of inappropriate antidiuretic hormone secretion and seizures. Neurology 2006;66:773-774 (Pubitemid 43739846)
7. Safdiah JE, Rudominer R. A case of hyponatremia induced bv duloxetine. J Clin Psychopharmacol 2006;26:675-676 (Pubitemid 44772754)
8. Christe C, Vogt N. SSRI-induced SIADH in older people. J Am Geriatr Soc 1999;47:630-631
9. Bouman WP, Pinner G, Johnson H. Incidence of selective serotonin reuptake inhibitor (SSRI) induced hyponatraemia due to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion in the elderly. Int J Geriatr Psychiatry 1998;13:12-15 (Pubitemid 28046024)
10. Liu BA, Mittmann N, Knowles SR et al. Hyponatremia and the syndrome of inappropriate secretion of antidiuretic hormone associated with the use of selective serotonin reuptake inhibitors: a review of spontaneous reports. CMAJ 1996;155:519-527 (Pubitemid 26316956)
11. Woo MH, Smythe MA. Association of SIADH with selective serotonin reuptake inhibitors. Ann Pharmacother 1997;31:108-110 (Pubitemid 27030075)
12. Jacob S, Spinler SA. Hyponatremia associated with selective serotonin-reuptake inhibitors in older adults. Ann Pharmacother 2006;40:1618-1622 (Pubitemid 44330206)
13. Twardowschy CA, Bertolucci CB, Gracia Cde M et al. Severe hyponatraemia and the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with fluoxetine: case report. Arq Neuropsiquiatr 2006;64:142-145
14. Dong X, Leppik IE, White J et al. Hyponatremia from oxcarbazepine and carbamazepine. Neurology 2005;65:1976-1978
15. Miller M. Syndromes of excess antidiuretic hormone release. Crit Care Clin 2001;17:11-23, v. (Pubitemid 32163176)
16. Chan TY. Drug induced syndrome of inappropriate antidiuretic hormone secretion. Causes, diagnosis and management. Drugs Aging 1997;11:27-44.
17. Blum A. The possible role of tobacco cigarette smoking in hyponatremia of long-term psychiatric patients. JAMA 1984;252:2864-2865 (Pubitemid 15219398)
18. Spigset O, Hedenmalm K. Hyponatraemia and the syndrome of inappropriate antidiuretic hormone secretion (SIADH) induced by psychotropic drugs. Drug Saf 1995;12:209-225
19. Arinzon ZH, Lehman YA, Fidelman ZG et al. Delayed recurrent SIADH associated with SSRIs. Ann Pharmacother 2002;36:1175-1177
20. Naranjo CA, Busto U, Sellers EM et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-245