Effects of genetic polymorphisms of N-acetyltransferase on trichloroethylene-induced hypersensitivity dermatitis among exposed workers

Industrial Health

Volumn 47, Issue 5, 2009, Pages 479-486

  Dai, Yufei ^a   Leng, Shuguang ^a   Li, Laiyu ^b   Niu, Yong ^a   Huang, Hanlin ^b   Liu, Qingjun ^a   Duan, Huawei ^a   Cheng, Juan ^a   Liu, Qing ^a   Zheng, Yuxin ^a  

^a CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b Center for Disease Control and Prevention of Guangdong Province   (China)

Author keywords

Genetic polymorphisms; Hypersensitivity dermatitis; N Acetyltransferase; Phenotype; Trichloroethylene

Indexed keywords

ACYLTRANSFERASE; ARYLAMINE ACETYLTRANSFERASE; TRICHLOROETHYLENE;

ACETYLATOR PHENOTYPE; ADULT; ARTICLE; CONTROLLED STUDY; DERMATITIS; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MALE; OCCUPATIONAL EXPOSURE; PHENOTYPE; SKIN ALLERGY; WORKER;

ADULT; ARYLAMINE N-ACETYLTRANSFERASE; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHINA; DERMATITIS, OCCUPATIONAL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; ISOENZYMES; LOGISTIC MODELS; MALE; PHENOTYPE; POLYMORPHISM, GENETIC; RISK FACTORS; TRICHLOROETHYLENE;

EID: 70350332392     PISSN: 00198366     EISSN: None     Source Type: Journal    
DOI: 10.2486/indhealth.47.479     Document Type: Article

References (41)

1. National Toxicology Program (1976) Carcinogenesis bioassay of trichloroethylene (CAS No. 79-01-6). Technical Report Series 2, 1-215.
2. National Toxicology Program (1990) NTP Carcinogenesis studies of trichloroethylene (without epichlorohydrin) in F344/N rats and B6C3F1 mice (gavage studies). Technical Report Series 243, 1-174.
3. McGregor DB, Heseltine E, Moller H (1995) Dry cleaning, some solvents used in dry cleaning and other industrial chemicals. IARC meeting, Lyon, 7-14 February 1995. Scand J Work Environ Health 21, 310-312
4. Lash LH, Fisher JW, Lipscomb JC, Parker JC (2000) Metabolism of trichloroethylene. Environ Health Perspect 108 (Suppl 2), 177-200.
5. Cummings BS, Lash LH (2000) Metabolism and toxicity of trichloroethylene and S-(1,2-dichlorovinyl)-L-cysteine in freshly isolated human proximal tubular cells. Toxicol Sci 53, 458-466
6. Cummings BS, Zangar RC, Novak RF, Lash LH (2000) Cytotoxicity of trichloroethylene and S-(1,2-dichlorovinyl)-L-cysteine in primary cultures of rat renal proximal tubular and distal tubular cells. Toxicology 150, 83-98.
7. Lash LH, Hueni SE, Putt DA (2001) Apoptosis, necrosis, and cell proliferation induced by S-(1,2-dichlorovinyl)-L-cysteine in primary cultures of human proximal tubular cells. Toxicol Appl Pharmacol 177, 1-16.
8. US Environmental Protection Agency (2001) Trichloroethylene Health Risk Assessment: Synthesis and Characterization, USEPA, Washington, DC.
9. Bruning T, Lammert M, Kempkes M, Thier R, Golka K, Bolt HM (1997) Influence of polymorphisms of GSTM1 and GSTT1 for risk of renal cell cancer in workers with long-term high occupational exposure to trichloroethylene. Arch Toxicol 71, 596-599 (Pubitemid 27339063)
10. Huang H, Li L, Chen B, Huang J, Kuang S (2002) New problems caused by occupational trichloroethylene exposure. Int J Immunnopathol Pharmacol 15, 30-32
11. Kamijima M, Hisanaga N, Wang H, Nakajima T (2007) Occupational trichloroethylene exposure as a cause of idiosyncratic generalized skin disorders and accompanying hepatitis similar to drug hypersensitivities. Int Arch Occup Environ Health 80, 357-370 (Pubitemid 46359458)
12. Huang H, Li L (2006) Study on general situation of occupational trichloroethylene-induced medicamentosa-like dermatitis. Chin Occup Med 33, 323-325 (in Chinese).
13. Goon AT, Lee LT, Tay YK, Yosipovitch G, Ng SK, Giam YC (2001) A case of trichloroethylene hypersensitivity syndrome. Arch Dermatol 137, 274-276 (Pubitemid 32240778)
14. Bond GR (1996) Hepatitis, rash and eosinophilia following trichloroethylene exposure: a case report and speculation on mechanistic similarity to halothane induced hepatitis. J Toxicol Clin Toxicol 34, 461-466
15. Bauer M, Rabens SF (1974) Cutaneous manifestations of trichloroethylene toxicity. Arch Dermatol 110, 886-890
16. Li L, Huang H, He J, Lin B, Chen B, Wang H, Kamijima M (2006) An occupational epidemiological survey on 150 cases of occupational medicamentosa-like dermatitis induced by trichloroethylene in Guangdong province, China. Chin Occup Med 33, 333-336 (in Chinese).
17. Huang H, Kamijima M, Wang H, Li S, Yoshikawa T, Lai G, Huang Z, Liu H, Chen J, Takeuchi Y, Nakajima T, Li L (2006) Human herpesvirus 6 reactivation in trichloroethylene-exposed workers suffering from generalized skin disorders accompanied by hepatic dysfunction. J Occup Health 48, 417-423 (Pubitemid 46057873)
18. Dai Y, Leng S, Li L, Niu Y, Huang H, Cheng J, Zheng Y (2004) Genetic polymorphism of cytokine genes and risk for trichloroethylene-induced severe generalized dermatitis: a case-control study. Biomarkers 9, 470-478 (Pubitemid 40403130)
19. Li H, Dai Y, Huang H, Li L, Leng S, Cheng J, Niu Y, Duan H, Liu Q, Zhang X, Huang X, Xie J, Feng Z, Wang J, He J, Zheng Y (2007) HLA-B*1301 as a biomarker for genetic susceptibility to hypersensitivity dermatitis induced by trichloroethylene among workers in China. Environ Health Perspect 115, 1553-1556
20. Schnuch A, Westphal GA, Müller MM, Schulz TG, Geier J, Brasch J, Merk HF, Kawakubo Y, Richter G, Koch P, Fuchs T, Gutgesell T, Reich K, Gebhardt M, Becker D, Grabbe J, Szliska C, Aberer W, Hallier E (1998) Genotype and phenotype of N-acetyltransferase 2 (NAT2) polymorphism in patients with contact allergy. Contact Dermatitis 38, 209-211 (Pubitemid 28156117)
21. Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16, 1215-1218
22. Deitz AC, Doll MA, Hein DW (1997) A restriction fragment length polymorphism assay that differentiates human N-acetyltransferase-1 (NAT1) alleles. Anal Biochem 253, 219-224
23. Hickman D, Sim E (1991) N-acetyltransferase polymorphism. Comparison of phenotype and genotype in humans. Biochem Pharmacol 42, 1007-1014
24. McCunney RJ (1988) Diverse manifestations of trichloroethylene. Br K Ind Med 45, 122-126
25. Hein DW, Doll MA, Fretland AF, Leff MA, Webb SJ, Xiao GH, Devanaboyina US, Nangju NA, Yi F (2000) Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms. Cancer Epidemiol Biomarkers Prev 9, 29-42.
26. Grant DM, Bell DA, Grewal R (1994) Functional analysis of variant alleles of human arylamine acetyltransferase NAT2 by heterologous expression in E. coli, 259, 10th International Symposium on Microsomes and Drug Oxidations, Toronto.
27. Hein DW, Ferguson RJ, Doll MA, Rustan TD, Gray K (1994) Molecular genetics of human polymorphic N-acetyltransferase: enzymatic analysis of 15 recombinant wild- type, mutant and chimeric NAT2 allozymes. HuM Mol Genet 3, 729-734
28. Hickman D, Palamanda JR, Unadkat JD, Sim E (1995) Enzyme kinetic properties of human recombinant arylamine N-acetyltransferase 2 allotypic variants expressed in Escherichia coli. Biochem Pharmacol 50, 697-703.
29. Bell DA, Badawi AF, Lang NP, Ilett KF, Kadlubar FF, Hirvonen A (1995) Polymorphism in the NAT1 polyadenylation signal: association of NAT1*10 allele with higher N-acetylation activity in bladder and colon tissue samples. Cancer Res 55, 5226-5229
30. Butcher NJ, Ilett KF, Minchin RF(1998) Functional polymorphism of the human arylamine N-acetyltransferase type 1 gene caused by C190T and G560A mutations. Pharmacogenetics 8, 67-72.
31. Hughes NC, Janezic SA, McQueen KL, Jewett MA, Castranio T, Bell DA, Grant DM (1998) Identification and characterization of variant alleles of human acetyltransferase NAT1 with defective function using p-aminosalicylate as an in-vivo and in-vitro probe. Pharmacogenetics 8, 55-56 (Pubitemid 28097602)
32. Scarpato R, Migliore L, Hirvonen A, Falck G, Norppa H (1996) Cytogenetic monitoring of occupational exposure to pesticides: characterization of GSTM1, GSTT1, and NAT2 genotypes. Environ Mol Mutagen 27, 263-269 (Pubitemid 26233412)
33. Wikman H, Thiel S, Jäger B, Schmezer P, Spiegelhaider B, Edler L, Dienemann H, Kayser K, Schulz V, Drings P, Bartsch H, Risch A (2001) Relevance of N-acetyltransferase 1 and 2 (NAT1, NAT2) genetic polymorphisms in non-small cell lung cancer susceptibility. Pharmacogenetics 11, 157-168 (Pubitemid 32216126)
34. Krajinovic M, Richer C, Sinnett H, Labuda D, Sinnett D (2000) Genetic polymorphisms of N-acetyltransferases 1 and 2 and gene-gene interaction in the susceptibility to childhood acute lymphoblastic leukemia 1. Cancer Epidemiol Biomarkers Prev 9, 557-562 (Pubitemid 30396176)
35. Cascorbi I, Drakoulis N, Brockmoller J, Maurer A, Sperling K, Roots I (1995) Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic activity. Am J Hum Genet 57, 581-592
36. Eyre RJ, Stevens DK, Parker JC, Bull RJ (1995) Renal activation of trichloroethene and S-(1,2-dichlorovinyl)-L-cysteine and cell proliferative responses in the kidneys of F344 rats and B6C3F1 mice. J Toxicol Environ Health 46, 465-481
37. Eyre RJ, Stevens DK, Parker JC, Bull RJ (1995) Acid-labile adducts to protein can be used as indicators of the cysteine S-conjugate pathway of trichloroethene metabolism. J Toxicol Environ Health 46, 443-464
38. Dietrich A, Kawakubo Y, Rzany B, Mockenhaupt M, Simon JC, Schopf E (1995) Low N-acetylating capacity in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis. Exp Dermatol 4, 313-316
39. Westphal GA, Reich K, Schulz TG, Neumann C, Hallier E, Schnuch A (2000) N-acetyltransferase 1 and 2 polymorphisms in para-substituted arylamine-induced contact allergy. Br J Dermatol 142, 1121-1127
40. Hein DW, Doll MA, Rustan TD, Gray K, Feng Y, Ferguson RJ, Grant DM (1993) Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases. Carcinogenesis 14, 1633-1638 (Pubitemid 23249371)
41. Vatsis KP, Weber WW, Bell DA, Dupret JM, Evans DA, Grant DM, Hein DW, Lin HJ, Meyer UA, Relling MV (1995) Nomenclature for N-acetyltransferases. Pharmacogenetics 5, 1-17.