메뉴 건너뛰기




Volumn 35, Issue 5, 2009, Pages 515-524

New anticoagulants for atrial fibrillation

Author keywords

Anticoagulants; Atrial fibrillation; Direct thrombin inhibitor; Factor Xa inhibitor; Stroke

Indexed keywords

ACETYLSALICYLIC ACID; AMIODARONE; ANTICOAGULANT AGENT; ANTIVITAMIN K; APIXABAN; ATI 5923; AZD 0837; BETRIXABAN; BLOOD CLOTTING FACTOR 10A INHIBITOR; BLOOD CLOTTING INHIBITOR; CLARITHROMYCIN; CYTOCHROME P450 3A4; DABIGATRAN ETEXILATE; DU 176B; GLYCOPROTEIN P INHIBITOR; HEPARIN; IDRABIOTAPARINUX; IDRAPARINUX; KETOCONAZOLE; QUINIDINE; RECOMBINANT BLOOD CLOTTING FACTOR 7A; RITONAVIR; RIVAROXABAN; UNCLASSIFIED DRUG; VORICONAZOLE; WARFARIN; XIMELAGATRAN; YM 150;

EID: 70350254762     PISSN: 00946176     EISSN: 10989064     Source Type: Journal    
DOI: 10.1055/s-0029-1234147     Document Type: Review
Times cited : (42)

References (49)
  • 1
    • 0035832261 scopus 로고    scopus 로고
    • Prevalence of diagnosed atrial fibrillation in adults: National implications for rhythm management and stroke prevention: The AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study
    • Go A S., Hylek E M., Phillips K A. et al. Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. JAMA 2001 285 (18) 2370-2375
    • (2001) JAMA , vol.285 , Issue.18 , pp. 2370-2375
    • Go, A.S.1    Hylek, E.M.2    Phillips, K.A.3
  • 2
    • 33747052359 scopus 로고    scopus 로고
    • Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence
    • Miyasaka Y, Barnes M E., Gersh B J. et al. Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence. Circulation 2006 114 (2) 119-125
    • (2006) Circulation , vol.114 , Issue.2 , pp. 119-125
    • Miyasaka, Y.1    Barnes, M.E.2    Gersh, B.J.3
  • 3
    • 0028244264 scopus 로고
    • Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation. Analysis of pooled data from five randomized controlled trials
    • Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation. Analysis of pooled data from five randomized controlled trials. Arch Intern Med 1994 154 (13) 1449-1457
    • (1994) Arch Intern Med , vol.154 , Issue.13 , pp. 1449-1457
  • 4
    • 0025779484 scopus 로고
    • Atrial fibrillation as an independent risk factor for stroke: The Framingham Study
    • Wolf P A., Abbott R D., Kannel W B. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991 22 (8) 983-988
    • (1991) Stroke , vol.22 , Issue.8 , pp. 983-988
    • Wolf, P.A.1    Abbott, R.D.2    Kannel, W.B.3
  • 5
    • 0037221236 scopus 로고    scopus 로고
    • Atrial fibrillation is associated with severe acute ischemic stroke
    • Dulli D A., Stanko H, Levine R L. Atrial fibrillation is associated with severe acute ischemic stroke. Neuroepidemiology 2003 22 (2) 118-123
    • (2003) Neuroepidemiology , vol.22 , Issue.2 , pp. 118-123
    • Dulli, D.A.1    Stanko, H.2    Levine, R.L.3
  • 6
    • 0029745023 scopus 로고    scopus 로고
    • Stroke severity in atrial fibrillation. the Framingham Study
    • Lin H J., Wolf P A., Kelly-Hayes M et al. Stroke severity in atrial fibrillation. The Framingham Study. Stroke 1996 27 (10) 1760-1764
    • (1996) Stroke , vol.27 , Issue.10 , pp. 1760-1764
    • Lin, H.J.1    Wolf, P.A.2    Kelly-Hayes, M.3
  • 8
    • 34347394385 scopus 로고    scopus 로고
    • Meta-analysis: Antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation
    • Hart R G., Pearce L A., Aguilar M I. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med 2007 146 (12) 857-867
    • (2007) Ann Intern Med , vol.146 , Issue.12 , pp. 857-867
    • Hart, R.G.1    Pearce, L.A.2    Aguilar, M.I.3
  • 9
    • 33646782452 scopus 로고    scopus 로고
    • Stroke prevention with aspirin, warfarin and ximelagatran in patients with non-valvular atrial fibrillation: A systematic review and meta-analysis
    • Lip G Y., Edwards S J. Stroke prevention with aspirin, warfarin and ximelagatran in patients with non-valvular atrial fibrillation: a systematic review and meta-analysis. Thromb Res 2006 118 (3) 321-333
    • (2006) Thromb Res , vol.118 , Issue.3 , pp. 321-333
    • Lip, G.Y.1    Edwards, S.J.2
  • 10
    • 33846970908 scopus 로고    scopus 로고
    • Newly detected atrial fibrillation and compliance with antithrombotic guidelines
    • Glazer N L., Dublin S, Smith N L. et al. Newly detected atrial fibrillation and compliance with antithrombotic guidelines. Arch Intern Med 2007 167 (3) 246-252
    • (2007) Arch Intern Med , vol.167 , Issue.3 , pp. 246-252
    • Glazer, N.L.1    Dublin, S.2    Smith, N.L.3
  • 11
    • 0033527355 scopus 로고    scopus 로고
    • Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: A meta-analysis
    • Hart R G., Benavente O, McBride R, Pearce L A. Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: a meta-analysis. Ann Intern Med 1999 131 (7) 492-501
    • (1999) Ann Intern Med , vol.131 , Issue.7 , pp. 492-501
    • Hart, R.G.1    Benavente, O.2    McBride, R.3    Pearce, L.A.4
  • 13
    • 0033593072 scopus 로고    scopus 로고
    • Warfarin use among ambulatory patients with nonvalvular atrial fibrillation: The anticoagulation and risk factors in atrial fibrillation (ATRIA) study
    • Go A S., Hylek E M., Borowsky L H., Phillips K A., Selby J V., Singer D E. Warfarin use among ambulatory patients with nonvalvular atrial fibrillation: the anticoagulation and risk factors in atrial fibrillation (ATRIA) study. Ann Intern Med 1999 131 (12) 927-934
    • (1999) Ann Intern Med , vol.131 , Issue.12 , pp. 927-934
    • Go, A.S.1    Hylek, E.M.2    Borowsky, L.H.3    Phillips, K.A.4    Selby, J.V.5    Singer, D.E.6
  • 14
    • 0344861847 scopus 로고    scopus 로고
    • Anticoagulation therapy for stroke prevention in atrial fibrillation: How well do randomized trials translate into clinical practice?
    • Go A S., Hylek E M., Chang Y et al. Anticoagulation therapy for stroke prevention in atrial fibrillation: how well do randomized trials translate into clinical practice? JAMA 2003 290 (20) 2685-2692
    • (2003) JAMA , vol.290 , Issue.20 , pp. 2685-2692
    • Go, A.S.1    Hylek, E.M.2    Chang, Y.3
  • 15
    • 0035851288 scopus 로고    scopus 로고
    • Prevalence and quality of warfarin use for patients with atrial fibrillation in the long-term care setting
    • McCormick D, Gurwitz J H., Goldberg R J. et al. Prevalence and quality of warfarin use for patients with atrial fibrillation in the long-term care setting. Arch Intern Med 2001 161 (20) 2458-2463
    • (2001) Arch Intern Med , vol.161 , Issue.20 , pp. 2458-2463
    • McCormick, D.1    Gurwitz, J.H.2    Goldberg, R.J.3
  • 16
    • 0034153308 scopus 로고    scopus 로고
    • Frequency of anticoagulation for atrial fibrillation and reasons for its non-use at a Veterans Affairs medical center
    • Bradley B C., Perdue K S., Tisdel K A., Gilligan D M. Frequency of anticoagulation for atrial fibrillation and reasons for its non-use at a Veterans Affairs medical center. Am J Cardiol 2000 85 (5) 568-572
    • (2000) Am J Cardiol , vol.85 , Issue.5 , pp. 568-572
    • Bradley, B.C.1    Perdue, K.S.2    Tisdel, K.A.3    Gilligan, D.M.4
  • 18
    • 15844410955 scopus 로고    scopus 로고
    • Evaluation of the pattern of treatment, level of anticoagulation control, and outcome of treatment with warfarin in patients with non-valvar atrial fibrillation: A record linkage study in a large British population
    • Jones M, McEwan P, Morgan C L., Peters J R., Goodfellow J, Currie C J. Evaluation of the pattern of treatment, level of anticoagulation control, and outcome of treatment with warfarin in patients with non-valvar atrial fibrillation: a record linkage study in a large British population. Heart 2005 91 (4) 472-477
    • (2005) Heart , vol.91 , Issue.4 , pp. 472-477
    • Jones, M.1    McEwan, P.2    Morgan, C.L.3    Peters, J.R.4    Goodfellow, J.5    Currie, C.J.6
  • 19
    • 52449129321 scopus 로고    scopus 로고
    • Warfarin for atrial fibrillation in community-based practise
    • Rose A J., Ozonoff A, Henault L E., Hylek E M. Warfarin for atrial fibrillation in community-based practise. J Thromb Haemost 2008 6 (10) 1647-1654
    • (2008) J Thromb Haemost , vol.6 , Issue.10 , pp. 1647-1654
    • Rose, A.J.1    Ozonoff, A.2    Henault, L.E.3    Hylek, E.M.4
  • 20
    • 34248531250 scopus 로고    scopus 로고
    • The interval between prothrombin time tests and the quality of oral anticoagulants treatment in patients with chronic atrial fibrillation
    • Shalev V, Rogowski O, Shimron O et al. The interval between prothrombin time tests and the quality of oral anticoagulants treatment in patients with chronic atrial fibrillation. Thromb Res 2007 120 (2) 201-206
    • (2007) Thromb Res , vol.120 , Issue.2 , pp. 201-206
    • Shalev, V.1    Rogowski, O.2    Shimron, O.3
  • 21
    • 0042387879 scopus 로고    scopus 로고
    • Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation
    • Hylek E M., Go A S., Chang Y et al. Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation. N Engl J Med 2003 349 (11) 1019-1026
    • (2003) N Engl J Med , vol.349 , Issue.11 , pp. 1019-1026
    • Hylek, E.M.1    Go, A.S.2    Chang, Y.3
  • 22
    • 33847006936 scopus 로고    scopus 로고
    • Comparison of outcomes among patients randomized to warfarin therapy according to anticoagulant control: Results from SPORTIF III and v
    • White H D., Gruber M, Feyzi J et al. Comparison of outcomes among patients randomized to warfarin therapy according to anticoagulant control: results from SPORTIF III and V. Arch Intern Med 2007 167 (3) 239-245
    • (2007) Arch Intern Med , vol.167 , Issue.3 , pp. 239-245
    • White, H.D.1    Gruber, M.2    Feyzi, J.3
  • 23
    • 34447522035 scopus 로고    scopus 로고
    • In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate
    • DOI 10.1160/TH07-03-0183
    • Wienen W, Stassen J M., Priepke H, Ries U J., Hauel N. In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate. Thromb Haemost 2007 98 (1) 155-162 (Pubitemid 47078782)
    • (2007) Thrombosis and Haemostasis , vol.98 , Issue.1 , pp. 155-162
    • Wienen, W.1    Stassen, J.-M.2    Priepke, H.3    Ries, U.J.4    Hauel, N.5
  • 24
    • 34548031359 scopus 로고    scopus 로고
    • The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects
    • Stangier J, Rathgen K, Stähle H, Gansser D, Roth W. The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects. Br J Clin Pharmacol 2007 64 (3) 292-303
    • (2007) Br J Clin Pharmacol , vol.64 , Issue.3 , pp. 292-303
    • Stangier, J.1    Rathgen, K.2    Stähle, H.3    Gansser, D.4    Roth, W.5
  • 25
    • 41949116970 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate
    • Stangier J. Clinical pharmacokinetics and pharmacodynamics of the oral direct thrombin inhibitor dabigatran etexilate. Clin Pharmacokinet 2008 47 (5) 285-295
    • (2008) Clin Pharmacokinet , vol.47 , Issue.5 , pp. 285-295
    • Stangier, J.1
  • 26
    • 49149130353 scopus 로고    scopus 로고
    • Dabigatran etexilate
    • Sanford M, Plosker G L. Dabigatran etexilate. Drugs 2008 68 (12) 1699-1709
    • (2008) Drugs , vol.68 , Issue.12 , pp. 1699-1709
    • Sanford, M.1    Plosker, G.L.2
  • 29
    • 57649123692 scopus 로고    scopus 로고
    • Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery
    • RE-MOBILIZE Writing Committee
    • Ginsberg J S., Davidson B L., Comp P C. et al, RE-MOBILIZE Writing Committee. Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery. J Arthroplasty 2009 24 (1) 1-9
    • (2009) J Arthroplasty , vol.24 , Issue.1 , pp. 1-9
    • Ginsberg, J.S.1    Davidson, B.L.2    Comp, P.C.3
  • 30
    • 35348879239 scopus 로고    scopus 로고
    • Dabigatran with or without concomitant aspirin compared with warfarin alone in patients with nonvalvular atrial fibrillation (PETRO Study)
    • Ezekowitz M D., Reilly P A., Nehmiz G et al. Dabigatran with or without concomitant aspirin compared with warfarin alone in patients with nonvalvular atrial fibrillation (PETRO Study). Am J Cardiol 2007 100 (9) 1419-1426
    • (2007) Am J Cardiol , vol.100 , Issue.9 , pp. 1419-1426
    • Ezekowitz, M.D.1    Reilly, P.A.2    Nehmiz, G.3
  • 31
    • 29144518504 scopus 로고    scopus 로고
    • Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939an oral, direct Factor Xa inhibitorafter multiple dosing in healthy male subjects
    • Kubitza D, Becka M, Wensing G, Voith B, Zuehlsdorf M. Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939an oral, direct Factor Xa inhibitorafter multiple dosing in healthy male subjects. Eur J Clin Pharmacol 2005 61 (12) 873-880
    • (2005) Eur J Clin Pharmacol , vol.61 , Issue.12 , pp. 873-880
    • Kubitza, D.1    Becka, M.2    Wensing, G.3    Voith, B.4    Zuehlsdorf, M.5
  • 32
    • 28744434950 scopus 로고    scopus 로고
    • Metabolism and distribution of (14C) BAY 59-7939an oral, direct factor Xa inhibitorin rat, dog and human [abstract 196]
    • Weinz C, Schwartz T, Pleiss U. Metabolism and distribution of (14C) BAY 59-7939an oral, direct factor Xa inhibitorin rat, dog and human [abstract 196]. Drug Metab Rev 2004 36 (suppl 1)
    • (2004) Drug Metab Rev , vol.36 , Issue.SUPPL 1
    • Weinz, C.1    Schwartz, T.2    Pleiss, U.3
  • 33
    • 57449094606 scopus 로고    scopus 로고
    • Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development
    • Eriksson B I., Quinlan D J., Weitz J I. Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development. Clin Pharmacokinet 2009 48 (1) 1-22
    • (2009) Clin Pharmacokinet , vol.48 , Issue.1 , pp. 1-22
    • Eriksson, B.I.1    Quinlan, D.J.2    Weitz, J.I.3
  • 34
    • 46049106502 scopus 로고    scopus 로고
    • Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: A double-blind, randomised controlled trial
    • RECORD2 Investigators
    • Kakkar A K., Brenner B, Dahl O E. et al, RECORD2 Investigators. Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double-blind, randomised controlled trial. Lancet 2008 372 (9632) 31-39
    • (2008) Lancet , vol.372 , Issue.9632 , pp. 31-39
    • Kakkar, A.K.1    Brenner, B.2    Dahl, O.E.3
  • 35
    • 45949099359 scopus 로고    scopus 로고
    • Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty
    • RECORD1 Study Group
    • Eriksson B I., Borris L C., Friedman R J. et al, RECORD1 Study Group. Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty. N Engl J Med 2008 358 (26) 2765-2775
    • (2008) N Engl J Med , vol.358 , Issue.26 , pp. 2765-2775
    • Eriksson, B.I.1    Borris, L.C.2    Friedman, R.J.3
  • 36
    • 45949103416 scopus 로고    scopus 로고
    • Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty
    • RECORD3 Investigators
    • Lassen M R., Ageno W, Borris L C. et al, RECORD3 Investigators. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty. N Engl J Med 2008 358 (26) 2776-2786
    • (2008) N Engl J Med , vol.358 , Issue.26 , pp. 2776-2786
    • Lassen, M.R.1    Ageno, W.2    Borris, L.C.3
  • 39
    • 58149458160 scopus 로고    scopus 로고
    • Apixaban metabolism and pharmacokinetics after oral administration to humans
    • Raghavan N, Frost C E., Yu Z et al. Apixaban metabolism and pharmacokinetics after oral administration to humans. Drug Metab Dispos 2009 37 (1) 74-81
    • (2009) Drug Metab Dispos , vol.37 , Issue.1 , pp. 74-81
    • Raghavan, N.1    Frost, C.E.2    Yu, Z.3
  • 40
    • 36348978071 scopus 로고    scopus 로고
    • The efficacy and safety of apixaban, an oral, direct factor Xa inhibitor, as thromboprophylaxis in patients following total knee replacement
    • Lassen M R., Davidson B L., Gallus A, Pineo G, Ansell J, Deitchman D. The efficacy and safety of apixaban, an oral, direct factor Xa inhibitor, as thromboprophylaxis in patients following total knee replacement. J Thromb Haemost 2007 5 (12) 2368-2375
    • (2007) J Thromb Haemost , vol.5 , Issue.12 , pp. 2368-2375
    • Lassen, M.R.1    Davidson, B.L.2    Gallus, A.3    Pineo, G.4    Ansell, J.5    Deitchman, D.6
  • 41
    • 42049103306 scopus 로고    scopus 로고
    • Late breaking clinical trial: A dose finding study of the oral direct factor xa inhibitor apixaban in the treatment of patients with acute symptomatic deep vein thrombosis the Botticelli Investigators
    • Abstract S-003
    • Buller H R. Late breaking clinical trial: a dose finding study of the oral direct factor xa inhibitor apixaban in the treatment of patients with acute symptomatic deep vein thrombosis The Botticelli Investigators. J Thromb Haemost 2007 5 (suppl 2) Abstract S-003
    • (2007) J Thromb Haemost , vol.5 , Issue.SUPPL 2
    • Buller, H.R.1
  • 42
    • 35048854973 scopus 로고    scopus 로고
    • Antithrombotic effects of factor Xa inhibition with DU-176b: Phase-I study of an oral, direct factor Xa inhibitor using an ex-vivo flow chamber
    • Zafar M U., Vorchheimer D A., Gaztanaga J et al. Antithrombotic effects of factor Xa inhibition with DU-176b: Phase-I study of an oral, direct factor Xa inhibitor using an ex-vivo flow chamber. Thromb Haemost 2007 98 (4) 883-888
    • (2007) Thromb Haemost , vol.98 , Issue.4 , pp. 883-888
    • Zafar, M.U.1    Vorchheimer, D.A.2    Gaztanaga, J.3
  • 43
    • 22844436957 scopus 로고    scopus 로고
    • Short- and long-acting synthetic pentasaccharides as antithrombotic agents
    • Walenga J M., Jeske W P., Fareed J. Short- and long-acting synthetic pentasaccharides as antithrombotic agents. Expert Opin Investig Drugs 2005 14 (7) 847-858
    • (2005) Expert Opin Investig Drugs , vol.14 , Issue.7 , pp. 847-858
    • Walenga, J.M.1    Jeske, W.P.2    Fareed, J.3
  • 44
    • 2642617786 scopus 로고    scopus 로고
    • Biochemical and pharmacological properties of SANORG 34006, a potent and long-acting synthetic pentasaccharide
    • Herbert J M., Hérault J P., Bernat A et al. Biochemical and pharmacological properties of SANORG 34006, a potent and long-acting synthetic pentasaccharide. Blood 1998 91 (11) 4197-4205
    • (1998) Blood , vol.91 , Issue.11 , pp. 4197-4205
    • Herbert, J.M.1    Hérault, J.P.2    Bernat, A.3
  • 45
    • 63049085301 scopus 로고    scopus 로고
    • Bioequipotency of idraparinux and biotinylated idraparinux after single dose in healthy subjects
    • [Abstract P-T-678] Abstract P-T-678
    • Trellu M, Perez Y, Ortiz J, Cheng S, Paty I. Bioequipotency of idraparinux and biotinylated idraparinux after single dose in healthy subjects. [Abstract P-T-678] J Thromb Haemost 2007 5 (suppl 1) Abstract P-T-678
    • (2007) J Thromb Haemost , vol.5 , Issue.SUPPL 1
    • Trellu, M.1    Perez, Y.2    Ortiz, J.3    Cheng, S.4    Paty, I.5
  • 47
    • 34548768174 scopus 로고    scopus 로고
    • Idraparinux versus standard therapy for venous thromboembolic disease
    • van Gogh Investigators
    • Buller H R., Cohen A T., Davidson B et al, van Gogh Investigators. Idraparinux versus standard therapy for venous thromboembolic disease. N Engl J Med 2007 357 (11) 1094-1104
    • (2007) N Engl J Med , vol.357 , Issue.11 , pp. 1094-1104
    • Buller, H.R.1    Cohen, A.T.2    Davidson, B.3
  • 48
    • 40749160810 scopus 로고    scopus 로고
    • Comparison of idraparinux with vitamin K antagonists for prevention of thromboembolism in patients with atrial fibrillation: A randomised, open-label, non-inferiority trial
    • Amadeus Investigators
    • Bousser M G., Bouthier J, Büller H R. et al, Amadeus Investigators. Comparison of idraparinux with vitamin K antagonists for prevention of thromboembolism in patients with atrial fibrillation: a randomised, open-label, non-inferiority trial. Lancet 2008 371 (9609) 315-321
    • (2008) Lancet , vol.371 , Issue.9609 , pp. 315-321
    • Bousser, M.G.1    Bouthier, J.2    Büller, H.R.3
  • 49
    • 70449390635 scopus 로고    scopus 로고
    • The utility of genotyping in the first evaluation of a novel vitamin K antagonist: ATI-5923
    • Abstract 4415
    • Ezekowitz M D., Milner P, Ellis D et al. The utility of genotyping in the first evaluation of a novel vitamin K antagonist: ATI-5923. Circulation 2008 118 (Suppl 885) Abstract 4415
    • (2008) Circulation , vol.118 , Issue.SUPPL 885
    • Ezekowitz, M.D.1    Milner, P.2    Ellis, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.