Protopathic bias in observational studies on statin effectiveness

European Journal of Clinical Pharmacology

Volumn 65, Issue 11, 2009, Pages 1167-1168

  Korhonen, Maarit Jaana ^a,b   Huupponen, Risto ^a,c   Ruokoniemi, Päivi ^a,d   Helin Salmivaara, Arja ^a,e  

^a UNIVERSITY OF TURKU   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c TURKU UNIVERSITY HOSPITAL   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

^e HOSPITAL DISTRICT OF HELSINKI AND UUSIMAA   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO;

ACUTE HEART INFARCTION; CORONARY ARTERY DISEASE; DRUG EFFICACY; HEART INFARCTION; HEART MUSCLE REVASCULARIZATION; HUMAN; LETTER; OBSERVER BIAS; PRIORITY JOURNAL;

DIABETIC ANGIOPATHIES; EVALUATION STUDIES AS TOPIC; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; MIDDLE AGED; SELECTION BIAS;

EID: 70350237065     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-009-0701-0     Document Type: Letter

References (6)

1. Cholesterol Treatment Trialists' (CTT) Collaborators 2008 Efficacy of cholesterol-lowering therapy in 18 686 people with diabetes in 14 randomised trials of statins: a meta-analysis Lancet 371 117 125 10.1016/S0140-6736(08) 60104-X
2. RJ Ligthelm V Borzi J Gumprecht R Kawamori Y Wenying P Valensi 2007 Importance of observational studies in clinical practice Clin Ther 29 1284 1292 10.1016/j.clinthera.2007.07.004 (Pubitemid 351181208)
3. H Tamim AA Monfared J LeLorier 2007 Application of lag-time into exposure definitions to control for protopathic bias Pharmacoepidemiol Drug Saf 16 250 258 10.1002/pds.1360 1:STN:280:DC%2BD2s7jsVeksQ%3D%3D 17245804 (Pubitemid 46431688)
4. A Helin-Salmivaara P Lavikainen MJ Korhonen H Halava SY Junnila R Kettunen PJ Neuvonen JE Martikainen P Ruokoniemi LK Saastamoinen L Virta R Huupponen 2008 Long-term persistence with statin therapy: a nationwide register-based study in Finland Clin Ther 30 Theme Issue 2228 2240 10.1016/j.clinthera.2008.12.003 19281917
5. L Smeeth I Douglas AJ Hall R Hubbard S Evans 2009 Effect of statins on a wide range of health outcomes: a cohort study validated by comparison with randomized trials Br J Clin Pharmacol 67 99 109 10.1111/j.1365-2125.2008.03308.x 19006546
6. S Perrault A Dragomir L Blais A Berard L Lalonde M White D Pilon 2009 Impact of better adherence to statin agents in the primary prevention of coronary artery disease Eur J Clin Pharmacol 10.1007/s00228-009-0673-0