Why gamblers fail to win: A review of cognitive and neuroimaging findings in pathological gambling

Neuroscience and Biobehavioral Reviews

Volumn 34, Issue 1, 2010, Pages 87-107

  van Holst, Ruth J ^a   van den Brink, Wim ^a   Veltman, Dick J ^a   Goudriaan, Anna E ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Addiction; Attentional bias; Cognition; Cue reactivity; Decision making; fMRI; Impulsivity; Neuroimaging; Neuropsychology; Pathological gambling; Punishment; Reward

Indexed keywords

FLUVOXAMINE; MODAFINIL; PLACEBO; SEROTONIN UPTAKE INHIBITOR;

ASSOCIATION; ATTENTION; ATTENTION DEFICIT DISORDER; COGNITION; COMORBIDITY; DECISION MAKING; DOPAMINE RELEASE; FEEDBACK SYSTEM; FRONTAL CORTEX; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; IMPULSE CONTROL DISORDER; IMPULSIVENESS; INSTRUMENTAL CONDITIONING; NEUROIMAGING; NEUROPSYCHOLOGICAL TEST; OBSESSIVE COMPULSIVE DISORDER; ORBITAL CORTEX; PARKINSON DISEASE; PATHOLOGICAL GAMBLING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; REVIEW; REWARD; SUBSTANCE ABUSE; WORKING MEMORY;

ANIMALS; ATTENTION; BRAIN; EXECUTIVE FUNCTION; GAMBLING; HUMANS; IMPULSIVE BEHAVIOR; REWARD;

EID: 70350225839     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2009.07.007     Document Type: Review

References (205)

1. Alessi S.M., and Petry N.M. Pathological gambling severity is associated with impulsivity in a delay discounting procedure. Behav. Processes 64 (2003) 345-354
2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (1994), American Psychiatric Association, Washington, DC
3. Aron A.R. The neural basis of inhibition in cognitive control. Neuroscientist 13 (2007) 214-228
4. Bari A.A., and Pierce R.C. D1-like and D2 dopamine receptor antagonists administered into the shell subregion of the rat nucleus accumbens decrease cocaine, but not food, reinforcement. Neuroscience 135 (2005) 959-968
5. Barry D., and Petry N.M. Predictors of decision-making on the Iowa Gambling Task: independent effects of lifetime history of substance use disorders and performance on the Trail Making Test. Brain Cogn. 66 3 (2008) 243-252
6. Bechara A., Damasio A.R., Damasio H., and Anderson S.W. Insensitivity to future consequences following damage to human prefrontal cortex. Cognition 50 (1994) 7-15
7. Bechara A., Tranel D., and Damasio H. Characterization of the decision-making deficit of patients with ventromedial prefrontal cortex lesions. Brain 123 Pt 11 (2000) 2189-2202
8. Berridge K.C., and Robinson T.E. What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?. Brain Res. Brain Res. Rev. 28 (1998) 309-369
9. Blair C. How similar are fluid cognition and general intelligence? A developmental neuroscience perspective on fluid cognition as an aspect of human cognitive ability. Behav. Brain Sci. 29 (2006) 109-125
10. Blaszczynski A., and Nower L. A pathways model of problem and pathological gambling. Addiction 97 (2002) 487-499
11. Bolla K., Ernst M., Kiehl K., Mouratidis M., Eldreth D., Contoreggi C., Matochik J., Kurian V., Cadet J., Kimes A., Funderburk F., and London E. Prefrontal cortical dysfunction in abstinent cocaine abusers. J. Neuropsychiatry Clin. Neurosci. 16 (2004) 456-464
12. Bolla K.I., Eldreth D.A., London E.D., Kiehl K.A., Mouratidis M., Contoreggi C., Matochik J.A., Kurian V., Cadet J.L., Kimes A.S., Funderburk F.R., and Ernst M. Orbitofrontal cortex dysfunction in abstinent cocaine abusers performing a decision-making task. Neuroimage 19 (2003) 1085-1094
13. Bolla K.I., Eldreth D.A., Matochik J.A., and Cadet J.L. Neural substrates of faulty decision-making in abstinent marijuana users. Neuroimage 26 (2005) 480-492
14. Boronat C.B., and Logan G.D. The role of attention in automatization: does attention operate at encoding, or retrieval, or both?. Mem. Cognit. 25 (1997) 36-46
15. Brand M., Kalbe E., Labudda K., Fujiwara E., Kessler J., and Markowitsch H.J. Decision-making impairments in patients with pathological gambling. Psychiatry Res. 133 (2005) 91-99
16. Brand M., Recknor E.C., Grabenhorst F., and Bechara A. Decisions under ambiguity and decisions under risk: correlations with executive functions and comparisons of two different gambling tasks with implicit and explicit rules. J. Clin. Exp. Neuropsychol. 29 (2007) 86-99
17. Braus D.F., Wrase J., Grusser S., Hermann D., Ruf M., Flor H., Mann K., and Heinz A. Alcohol-associated stimuli activate the ventral striatum in abstinent alcoholics. J. Neural Transm. 108 (2001) 887-894
18. Brown J.W., and Braver T.S. Risk prediction and aversion by anterior cingulate cortex. Cogn. Affect. Behav. Neurosci. 7 (2007) 266-277
19. Busemeyer J.R., and Stout J.C. A contribution of cognitive decision models to clinical assessment: decomposing performance on the Bechara gambling task. Psychol. Assess. 14 (2002) 253-262
20. Caine S.B., Negus S.S., Mello N.K., Patel S., Bristow L., Kulagowski J., Vallone D., Saiardi A., and Borrelli E. Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists. J. Neurosci. 22 (2002) 2977-2988
21. Carter B.L., and Tiffany S.T. Cue-reactivity and the future of addiction research. Addiction 94 (1999) 349-351
22. Carter C.S., and van Veen V. Anterior cingulate cortex and conflict detection: an update of theory and data. Cogn. Affect. Behav. Neurosci. 7 (2007) 367-379
23. Carver C.S., and White T.L. Behavioral inhibition, behavioral activation, and affective responses to impending reward and punishment: the BIS/BAS Scales. [References]. J. Pers. Soc. Psychol. (1994) 319-333
24. Cavedini P., Riboldi G., Keller R., D'Annucci A., and Bellodi L. Frontal lobe dysfunction in pathological gambling patients. Biol. Psychiatry 51 (2002) 334-341
25. Chiu Y.C., and Lin C.H. Is deck C an advantageous deck in the Iowa Gambling Task?. Behav. Brain Funct. 3 (2007) 37
26. Chong T.T., Williams M.A., Cunnington R., and Mattingley J.B. Selective attention modulates inferior frontal gyrus activity during action observation. Neuroimage 40 1 (2008) 298-307
27. Clark L., Cools R., and Robbins T.W. The neuropsychology of ventral prefrontal cortex: decision-making and reversal learning. Brain Cogn. 55 (2004) 41-53
28. Clark L., Lawrence A.J., Astley-Jones F., and Gray N. Gambling near-misses enhance motivation to gamble and recruit win-related brain circuitry. Neuron 61 3 (2009) 481-490
29. Cocco N., Sharpe L., and Blaszczynski A.P. Differences in preferred level of arousal in two sub-groups of problem gamblers: a preliminary report. J. Gambl. Stud. (1995) 221-229
30. Coventry K.R. Mood state, arousal, decision making, and persistence at gaming. Addiction 96 (2001) 1860-1861
31. Cox W.M., Fadardi J.S., and Pothos E.M. The addiction-Stroop test: theoretical considerations and procedural recommendations. Psychol. Bull. 132 (2006) 443-476
32. Crockford D.N., Goodyear B., Edwards J., Quickfall J., and el-Guebaly N. Cue-induced brain activity in pathological gamblers. Biol. Psychiatry 58 (2005) 787-795
33. Damasio A.R. The somatic marker hypothesis and the possible functions of the prefrontal cortex. Philos. Trans. R. Soc. Lond. B: Biol. Sci. 351 (1996) 1413-1420
34. de Ruiter M.B., Veltman D.J., Goudriaan A.E., Oosterlaan J., Sjoerds Z., and van den Brink W. Response perseveration and ventral prefrontal sensitivity to reward and punishment in male problem gamblers and smokers. Neuropsychopharmacology 34 4 (2009) 1027-1038
35. Dixon M.R., Marley J., and Jacobs E.A. Delay discounting by pathological gamblers. J. Appl. Behav. Anal. 36 (2003) 449-458
36. Dom G., De W.B., Hulstijn W., van den Brink W., and Sabbe B. Decision-making deficits in alcohol-dependent patients with and without comorbid personality disorder. Alcohol. Clin. Exp. Res. 30 (2006) 1670-1677
37. Dretsch M.N., and Tipples J. Working memory involved in predicting future outcomes based on past experiences. Brain Cogn. 66 (2008) 83-90
38. Dunn B.D., Dalgleish T., and Lawrence A.D. The somatic marker hypothesis: a critical evaluation. Neurosci. Biobehav. Rev. 30 (2006) 239-271
39. DuPaul G.J., Guevremont D.C., and Barkley R.A. Behavioral treatment of attention-deficit hyperactivity disorder in the classroom. The use of the attention training system. Behav. Modif. 16 (1992) 204-225
40. Egner T., and Hirsch J. The neural correlates and functional integration of cognitive control in a Stroop task. Neuroimage 24 (2005) 539-547
41. Ehrman R.N., Robbins S.J., Bromwell M.A., Lankford M.E., Monterosso J.R., and O'Brien C.P. Comparing attentional bias to smoking cues in current smokers, former smokers, and non-smokers using a dot-probe task. Drug Alcohol Depend. 67 (2002) 185-191
42. Eisen S.A., Slutske W.S., Lyons M.J., Lassman J., Xian H., Toomey R., Chantarujikapong S., and Tsuang M.T. The genetics of pathological gambling. Semin. Clin. Neuropsychiatry 6 (2001) 195-204
43. Ernst M., Bolla K., Mouratidis M., Contoreggi C., Matochik J.A., Kurian V., Cadet J.L., Kimes A.S., and London E.D. Decision-making in a risk-taking task: a PET study. Neuropsychopharmacology 26 (2002) 682-691
44. Ersche K.D., Fletcher P.C., Lewis S.J., Clark L., Stocks-Gee G., London M., Deakin J.B., Robbins T.W., and Sahakian B.J. Abnormal frontal activations related to decision-making in current and former amphetamine and opiate dependent individuals. Psychopharmacology (Berl.) 180 (2005) 612-623
45. Everitt B.J., Belin D., Economidou D., Pelloux Y., Dalley J.W., and Robbins T.W. Review. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction. Philos. Trans. R. Soc. Lond. B: Biol. Sci. 363 (2008) 3125-3135
46. Everitt B.J., and Robbins T.W. Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat. Neurosci. 8 (2005) 1481-1489
47. Eysenck M.W. Extraversion, arousal, and speed of retrieval from secondary storage. J. Pers. 43 (1975) 390-401
48. Fellows L.K., and Farah M.J. Different underlying impairments in decision-making following ventromedial and dorsolateral frontal lobe damage in humans. Cereb. Cortex 15 (2005) 58-63
49. Field M., and Cox W.M. Attentional bias in addictive behaviors: a review of its development, causes, and consequences. Drug Alcohol Depend. 97 (2008) 1-20
50. Field M., and Eastwood B. Experimental manipulation of attentional bias increases the motivation to drink alcohol. Psychopharmacology (Berl.) 183 (2005) 350-357
51. Fillmore M.T., and Rush C.R. Impaired inhibitory control of behavior in chronic cocaine users. Drug Alcohol Depend. 66 (2002) 265-273
52. Forbush K.T., Shaw M., Graeber M.A., Hovick L., Meyer V.J., Moser D.J., Bayless J., Watson D., and Black D.W. Neuropsychological characteristics and personality traits in pathological gambling. CNS Spectr. 13 (2008) 306-315
53. Frank M.J., and Claus E.D. Anatomy of a decision: striato-orbitofrontal interactions in reinforcement learning, decision making, and reversal. Psychol. Rev. 113 (2006) 300-326
54. Franken I.H. Drug craving and addiction: integrating psychological and neuropsychopharmacological approaches. Prog. Neuropsychopharmacol. Biol. Psychiatry 27 (2003) 563-579
55. Franken I.H., Booij J., and van den Brink W. The role of dopamine in human addiction: from reward to motivated attention. Eur. J. Pharmacol. 526 (2005) 199-206
56. Franken I.H., Hendriks V.M., Stam C.J., and van den Brink W. A role for dopamine in the processing of drug cues in heroin dependent patients. Eur. Neuropsychopharmacol. 14 (2004) 503-508
57. Fregni F., Liguori P., Fecteau S., Nitsche M.A., Pascual-Leone A., and Boggio P.S. Cortical stimulation of the prefrontal cortex with transcranial direct current stimulation reduces cue-provoked smoking craving: a randomized, sham-controlled study. J. Clin. Psychiatry 69 (2008) 32-40
58. Fuentes D., Tavares H., Artes R., and Gorenstein C. Self-reported and neuropsychological measures of impulsivity in pathological gambling. J. Int. Neuropsychol. Soc. 12 (2006) 907-912
59. Garavan H., Pankiewicz J., Bloom A., Cho J.K., Sperry L., Ross T.J., Salmeron B.J., Risinger R., Kelley D., and Stein E.A. Cue-induced cocaine craving: neuroanatomical specificity for drug users and drug stimuli. Am. J. Psychiatry 157 (2000) 1789-1798
60. George M.S., Anton R.F., Bloomer C., Teneback C., Drobes D.J., Lorberbaum J.P., Nahas Z., and Vincent D.J. Activation of prefrontal cortex and anterior thalamus in alcoholic subjects on exposure to alcohol-specific cues. Arch. Gen. Psychiatry 58 (2001) 345-352
61. Goldstein R.Z., Tomasi D., Rajaram S., Cottone L.A., Zhang L., Maloney T., Telang F., ia-Klein N., and Volkow N.D. Role of the anterior cingulate and medial orbitofrontal cortex in processing drug cues in cocaine addiction. Neuroscience 144 (2007) 1153-1159
62. Goldstein R.Z., and Volkow N.D. Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. Am. J. Psychiatry 159 (2002) 1642-1652
63. Gordon M., and Mettelman B.B. The assessment of attention: I. Standardization and reliability of a behavior-based measure. J. Clin. Psychol. 44 5 (1988) 682-690
64. Goudriaan A.E., Oosterlaan J., de Beurs E., and van den Brink W. Pathological gambling: a comprehensive review of biobehavioral findings. Neurosci. Biobehav. Rev. 28 (2004) 123-141
65. Goudriaan A.E., Oosterlaan J., de Beurs E., and van den Brink W. Neurocognitive functions in pathological gambling: a comparison with alcohol dependence, Tourette syndrome and normal controls. Addiction 101 (2006) 534-547
66. Goudriaan A.E., Oosterlaan J., de Beurs E., and van den Brink W. Decision making in pathological gambling: a comparison between pathological gamblers, alcohol dependents, persons with Tourette syndrome, and normal controls. Brain Res. Cogn. Brain Res. 23 (2005) 137-151
67. Goudriaan A.E., Oosterlaan J., de Beurs E., and van den Brink W. The role of self-reported impulsivity and reward sensitivity versus neurocognitive measures of disinhibition and decision-making in the prediction of relapse in pathological gamblers. Psychol. Med. 38 (2008) 41-50
68. Grant J.E., Kim S.W., and Hartman B.K. A double-blind, placebo-controlled study of the opiate antagonist naltrexone in the treatment of pathological gambling urges. J. Clin. Psychiatry 69 (2008) 783-789
69. Grant J.E., Kim S.W., and Odlaug B.L. N-acetyl cysteine, a glutamate-modulating agent, in the treatment of pathological gambling: a pilot study. Biol. Psychiatry 62 (2007) 652-657
70. Grusser S.M., Wrase J., Klein S., Hermann D., Smolka M.N., Ruf M., Weber-Fahr W., Flor H., Mann K., Braus D.F., and Heinz A. Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics. Psychopharmacology (Berl.) 175 (2004) 296-302
71. Hampton A.N., Adolphs R., Tyszka M.J., and O'doherty J.P. Contributions of the amygdala to reward expectancy and choice signals in human prefrontal cortex. Neuron 55 (2007) 545-555
72. Hampton A.N., and O'doherty J.P. Decoding the neural substrates of reward-related decision making with functional MRI. Proc. Natl. Acad. Sci. U.S.A. 104 (2007) 1377-1382
73. Heinz A., Siessmeier T., Wrase J., Hermann D., Klein S., Grusser S.M., Flor H., Braus D.F., Buchholz H.G., Grunder G., Schreckenberger M., Smolka M.N., Rosch F., Mann K., and Bartenstein P. Correlation between dopamine D(2) receptors in the ventral striatum and central processing of alcohol cues and craving. Am. J. Psychiatry 161 (2004) 1783-1789
74. Heinz A., Wrase J., Kahnt T., Beck A., Bromand Z., Grusser S.M., Kienast T., Smolka M.N., Flor H., and Mann K. Brain activation elicited by affectively positive stimuli is associated with a lower risk of relapse in detoxified alcoholic subjects. Alcohol. Clin. Exp. Res. 31 (2007) 1138-1147
75. Hester R., and Garavan H. Executive dysfunction in cocaine addiction: evidence for discordant frontal, cingulate, and cerebellar activity. J. Neurosci. 24 (2004) 11017-11022
76. Hinson J.M., Jameson T.L., and Whitney P. Somatic markers, working memory, and decision making. Cogn. Affect. Behav. Neurosci. 2 (2002) 341-353
77. Hoffman W.F., Moore M., Templin R., McFarland B., Hitzemann R.J., and Mitchell S.H. Neuropsychological function and delay discounting in methamphetamine-dependent individuals. Psychopharmacology (Berl.) 188 (2006) 162-170
78. Hollander E., Pallanti S., Baldini R.N., Sood E., Baker B.R., and Buchsbaum M.S. Imaging monetary reward in pathological gamblers. World J. Biol. Psychiatry 6 (2005) 113-120
79. Hollander E., Sood E., Pallanti S., Baldini-Rossi N., and Baker B. Pharmacological treatments of pathological gambling. J. Gambl. Stud. 21 (2005) 99-110
80. Ibanez A., Blanco C., Perez dC I., Fernandez-Piqueras J., and Saiz-Ruiz J. Genetics of pathological gambling. J. Gambl. Stud. 19 (2003) 11-22
81. Jameson T.L., Hinson J.M., and Whitney P. Components of working memory and somatic markers in decision making. Psychon. Bull. Rev. 11 (2004) 515-520
82. Joukhador J., Maccallum F., and Blaszczynski A. Differences in cognitive distortions between problem and social gamblers. Psychol. Rep. 92 (2003) 1203-1214
83. Kalechstein A.D., Fong T., Rosenthal R.J., Davis A., Vanyo H., and Newton T.F. Pathological gamblers demonstrate frontal lobe impairment consistent with that of methamphetamine-dependent individuals. J. Neuropsychiatry Clin. Neurosci. 19 (2007) 298-303
84. Kalivas P.W., and Volkow N.D. The neural basis of addiction: a pathology of motivation and choice. Am. J. Psychiatry 162 (2005) 1403-1413
85. Keith J.A., Spurgeon J.H., Blair S.N., and Carter L.W. Motivational differentials among physically active and inactive mature males as measured by the motivational analysis test. Res. Q. 45 (1974) 217-223
86. Keitz M., Koerts J., Kortekaas R., Renken R., de Jong B.M., and Leenders K.L. Prefrontal cortex and striatal activation by feedback in Parkinson's disease. Brain Res. 1236 (2008) 225-233
87. Kertzman S., Lowengrub K., Aizer A., Nahum Z.B., Kotler M., and Dannon P.N. Stroop performance in pathological gamblers. Psychiatry Res. 142 (2006) 1-10
88. Kertzman S., Lowengrub K., Aizer A., Vainder M., Kotler M., and Dannon P.N. Go-no-go performance in pathological gamblers. Psychiatry Res. 161 (2008) 1-10
89. Kessler J., Mielke R., Grond M., Herholz K., and Heiss W.D. Frontal lobe tasks do not reflect frontal lobe function in patients with probable Alzheimer's disease. Int. J. Neurosci. 104 (2000) 1-15
90. Kihara K., Hirose N., Mima T., Abe M., Fukuyama H., and Osaka N. The role of left and right intraparietal sulcus in the attentional blink: a transcranial magnetic stimulation study. Exp. Brain Res. 178 (2007) 135-140
91. Killgore W.D., Grugle N.L., Killgore D.B., Leavitt B.P., Watlington G.I., McNair S., and Balkin T.J. Restoration of risk-propensity during sleep deprivation: caffeine, dextroamphetamine, and modafinil. Aviat. Space Environ. Med. 79 (2008) 867-874
92. Kim S.W., and Grant J.E. An open naltrexone treatment study in pathological gambling disorder. Int. Clin. Psychopharmacol. 16 (2001) 285-289
93. Kim S.W., Grant J.E., Adson D.E., and Shin Y.C. Double-blind naltrexone and placebo comparison study in the treatment of pathological gambling. Biol. Psychiatry 49 (2001) 914-921
94. Kirby K.N., and Petry N.M. Heroin and cocaine abusers have higher discount rates for delayed rewards than alcoholics or non-drug-using controls. Addiction 99 (2004) 461-471
95. Knutson B., and Cooper J.C. Functional magnetic resonance imaging of reward prediction. Curr. Opin. Neurol. 18 (2005) 411-417
96. Knutson B., Fong G.W., Adams C.M., Varner J.L., and Hommer D. Dissociation of reward anticipation and outcome with event-related fMRI. Neuroreport 12 (2001) 3683-3687
97. Knutson B., Fong G.W., Bennett S.M., Adams C.M., and Hommer D. A region of mesial prefrontal cortex tracks monetarily rewarding outcomes: characterization with rapid event-related fMRI. Neuroimage 18 (2003) 263-272
98. Knutson B., Taylor J., Kaufman M., Peterson R., and Glover G. Distributed neural representation of expected value. J. Neurosci. 25 (2005) 4806-4812
99. Knutson B., and Wimmer G.E. Splitting the difference: how does the brain code reward episodes?. Ann. N. Y. Acad. Sci. 1104 (2007) 54-69
100. Krawczyk D.C. Contributions of the prefrontal cortex to the neural basis of human decision making. Neurosci. Biobehav. Rev. 26 (2002) 631-664
101. Krueger F., Fischer R., Heinecke A., and Hagendorf H. An fMRI investigation into the neural mechanisms of spatial attentional selection in a location-based negative priming task. Brain Res. 1174 (2007) 110-119
102. Krupitsky E.M., Neznanova O., Masalov D., Burakov A.M., Didenko T., Romanova T., Tsoy M., Bespalov A., Slavina T.Y., Grinenko A.A., Petrakis I.L., Pittman B., Gueorguieva R., Zvartau E.E., and Krystal J.H. Effect of memantine on cue-induced alcohol craving in recovering alcohol-dependent patients. Am. J. Psychiatry 164 (2007) 519-523
103. Labudda K., Wolf O.T., Markowitsch H.J., and Brand M. Decision-making and neuroendocrine responses in pathological gamblers. Psychiatry Res. 153 (2007) 233-243
104. Ladouceur R., Sylvain C., Boutin C., Lachance S., Doucet C., and Leblond J. Group therapy for pathological gamblers: a cognitive approach. Behav. Res. Ther. 41 (2003) 587-596
105. Ladouceur R., Sylvain C., Boutin C., Lachance S., Doucet C., Leblond J., and Jacques C. Cognitive treatment of pathological gambling. J. Nerv. Ment. Dis. 189 (2001) 774-780
106. Lakey C.E., Goodie A.S., and Campbell W.K. Frequent card playing and pathological gambling: the utility of the Georgia Gambling Task and Iowa Gambling Task for predicting pathology. J. Gambl. Stud. 23 (2007) 285-297
107. LaLumiere R.T., and Kalivas P.W. Glutamate release in the nucleus accumbens core is necessary for heroin seeking. J. Neurosci. 28 (2008) 3170-3177
108. Ledgerwood D.M., and Petry N.M. What do we know about relapse in pathological gambling?. Clin. Psychol. Rev. 26 (2006) 216-228
109. Ledgerwood D.M., and Petry N.M. Psychological experience of gambling and subtypes of pathological gamblers. Psychiatry Res. 144 (2006) 17-27
110. Leiserson V., and Pihl R.O. Reward-sensitivity, inhibition of reward-seeking, and dorsolateral prefrontal working memory function in problem gamblers not in treatment. J. Gambl. Stud. 23 (2007) 435-455
111. Lesieur H.R.B.S.B. The South Oaks Gambling Screen (SOGS): a new instrument for the identification of pathological gamblers. Am. J. Psychiatry 144 (1987) 1184-1188
112. Leung K.S., and Cottler L.B. Treatment of pathological gambling. Curr. Opin. Psychiatry 22 (2009) 69-74
113. Lin C.H., Chiu Y.C., Lee P.L., and Hsieh J.C. Is deck B a disadvantageous deck in the Iowa Gambling Task?. Behav. Brain Funct. 3 (2007) 16
114. Lineweaver T.T., Bond M.W., Thomas R.G., and Salmon D.P. A normative study of Nelson's (1976) modified version of the Wisconsin Card Sorting Test in healthy older adults. Clin. Neuropsychol. 13 (1999) 328-347
115. Linnet J., Rojskjaer S., Nygaard J., and Maher B.A. Episodic chasing in pathological gamblers using the Iowa gambling task. Scand. J. Psychol. 47 (2006) 43-49
116. Luman M., Oosterlaan J., and Sergeant J.A. The impact of reinforcement contingencies on AD/HD: a review and theoretical appraisal. Clin. Psychol. Rev. 25 (2005) 183-213
117. Machina M.J. Decision-making in the presence of risk. Science 236 (1987) 537-543
118. MacKillop J., Anderson E.J., Castelda B.A., Mattson R.E., and Donovick P.J. Divergent validity of measures of cognitive distortions, impulsivity, and time perspective in pathological gambling. J. Gambl. Stud. 22 (2006) 339-354
119. MacLeod C., Rutherford E., Campbell L., Ebsworthy G., and Holker L. Selective attention and emotional vulnerability: assessing the causal basis of their association through the experimental manipulation of attentional bias. J. Abnorm. Psychol. 111 (2002) 107-123
120. Manes F., Sahakian B., Clark L., Rogers R., Antoun N., Aitken M., and Robbins T. Decision-making processes following damage to the prefrontal cortex. Brain 125 (2002) 624-639
121. Mann K., Kiefer F., Spanagel R., and Littleton J. Acamprosate: recent findings and future research directions. Alcohol. Clin. Exp. Res. 32 (2008) 1105-1110
122. Marazziti D., Catena D.M., Conversano C., Consoli G., Vivarelli L., Mungai F., Di N.E., and Golia F. Executive function abnormalities in pathological gamblers. Clin. Pract. Epidemol. Ment. Health 4 (2008) 7
123. McClure S.M., York M.K., and Montague P.R. The neural substrates of reward processing in humans: the modern role of FMRI. Neuroscientist 10 (2004) 260-268
124. McFarland K., Lapish C.C., and Kalivas P.W. Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior. J. Neurosci. 23 (2003) 3531-3537
125. Meyer G., Schwertfeger J., Exton M.S., Janssen O.E., Knapp W., Stadler M.A., Schedlowski M., and Kruger T.H. Neuroendocrine response to casino gambling in problem gamblers. Psychoneuroendocrinology 29 (2004) 1272-1280
126. Minzenberg M.J., and Carter C.S. Modafinil: a review of neurochemical actions and effects on cognition. Neuropsychopharmacology 33 (2008) 1477-1502
127. Modesto-Lowe V., and Van K.J. Clinical uses of naltrexone: a review of the evidence. Exp. Clin. Psychopharmacol. 10 (2002) 213-227
128. Monaghan S., Blaszczynski A., and Nower L. Consequences of winning: the role of gambling outcomes in the development of irrational beliefs. Behav. Cogn. Psychother. 37 (2009) 49-59
129. Monterosso J.R., Ainslie G., Xu J., Cordova X., Domier C.P., and London E.D. Frontoparietal cortical activity of methamphetamine-dependent and comparison subjects performing a delay discounting task. Hum. Brain Mapp. 28 (2007) 383-393
130. Monterosso J.R., Aron A.R., Cordova X., Xu J., and London E.D. Deficits in response inhibition associated with chronic methamphetamine abuse. Drug Alcohol Depend. 79 (2005) 273-277
131. Nader M.A., Morgan D., Gage H.D., Nader S.H., Calhoun T.L., Buchheimer N., Ehrenkaufer R., and Mach R.H. PET imaging of dopamine D2 receptors during chronic cocaine self-administration in monkeys. Nat. Neurosci. 9 (2006) 1050-1056
132. Nelson H.E. A modified card sorting test sensitive to frontal lobe defects. Cortex 12 (1976) 313-324
133. Patton J.H., Stanford M.S., and Barratt E.S. Factor structure of the Barratt Impulsiveness Scale. J. Clin. Psychol. 51 (1995) 768-774
134. Paulus M.P., Hozack N., Frank L., Brown G.G., and Schuckit M.A. Decision making by methamphetamine-dependent subjects is associated with error-rate-independent decrease in prefrontal and parietal activation. Biol. Psychiatry 53 (2003) 65-74
135. Paulus M.P., Tapert S.F., and Schuckit M.A. Neural activation patterns of methamphetamine-dependent subjects during decision making predict relapse. Arch. Gen. Psychiatry 62 (2005) 761-768
136. Petrovic P., Pleger B., Seymour B., Kloppel S., De M.B., Critchley H., and Dolan R.J. Blocking central opiate function modulates hedonic impact and anterior cingulate response to rewards and losses. J. Neurosci. 28 (2008) 10509-10516
137. Petry N.M. Gambling and substance use disorders: current status and future directions. Am. J. Addict. 16 (2007) 1-9
138. Petry N.M. Pathological gamblers, with and without substance use disorders, discount delayed rewards at high rates. J. Abnorm. Psychol. 110 (2001) 482-487
139. Petry N.M. Substance abuse, pathological gambling, and impulsiveness. Drug Alcohol Depend. 63 (2001) 29-38
140. Petry N.M. Should the scope of addictive behaviors be broadened to include pathological gambling?. Addiction 101 Suppl. 1 (2006) 152-160
141. Petry N.M., Ammerman Y., Bohl J., Doersch A., Gay H., Kadden R., Molina C., and Steinberg K. Cognitive-behavioral therapy for pathological gamblers. J. Consult. Clin. Psychol. 74 (2006) 555-567
142. Petry N.M., and Casarella T. Excessive discounting of delayed rewards in substance abusers with gambling problems. Drug Alcohol Depend. 56 (1999) 25-32
143. Petry N.M., Litt M.D., Kadden R., and Ledgerwood D.M. Do coping skills mediate the relationship between cognitive-behavioral therapy and reductions in gambling in pathological gamblers?. Addiction 102 (2007) 1280-1291
144. Posner M.I., Snyder C.R., and Davidson B.J. Attention and the detection of signals. J. Exp. Psychol. Gen. 109 (1980) 160-174
145. Potenza M.N. The neurobiology of pathological gambling. Semin. Clin. Neuropsychiatry 6 (2001) 217-226
146. Potenza M.N. Review. The neurobiology of pathological gambling and drug addiction: an overview and new findings. Philos. Trans. R. Soc. Lond. B: Biol. Sci. 363 1507 (2008) 3181-3189
147. Potenza M.N. Should addictive disorders include non-substance-related conditions?. Addiction 101 Suppl. 1 (2006) 142-151
148. Potenza M.N., Leung H.C., Blumberg H.P., Peterson B.S., Fulbright R.K., Lacadie C.M., Skudlarski P., and Gore J.C. An FMRI Stroop task study of ventromedial prefrontal cortical function in pathological gamblers. Am. J. Psychiatry 160 (2003) 1990-1994
149. Potenza M.N., Steinberg M.A., Skudlarski P., Fulbright R.K., Lacadie C.M., Wilber M.K., Rounsaville B.J., Gore J.C., and Wexler B.E. Gambling urges in pathological gambling: a functional magnetic resonance imaging study. Arch. Gen. Psychiatry 60 (2003) 828-836
150. Putman P., Hermans E., and van Honk J. Emotional Stroop performance for masked angry faces: It's BAS, Not BIS. [References]. Emotion 4 (2004) 305-311
151. Rapport M.D., Loo S., Isaacs P., Goya S., Denney C., and Scanlan S. Methylphenidate and attentional training. Comparative effects on behavior and neurocognitive performance in twin girls with attention-deficit/hyperactivity disorder. Behav. Modif. 20 (1996) 428-430
152. Ratti M.T., Bo P., Giardini A., and Soragna D. Chronic alcoholism and the frontal lobe: which executive functions are imparied?. Acta Neurol. Scand. 105 (2002) 276-281
153. Redish A.D., Jensen S., Johnson A., and Kurth-Nelson Z. Reconciling reinforcement learning models with behavioral extinction and renewal: implications for addiction, relapse, and problem gambling. Psychol. Rev. 114 (2007) 784-805
154. Regard M., Knoch D., Gutling E., and Landis T. Brain damage and addictive behavior: a neuropsychological and electroencephalogram investigation with pathologic gamblers. Cogn. Behav. Neurol. 16 (2003) 47-53
155. Reuter J., Raedler T., Rose M., Hand I., Glascher J., and Buchel C. Pathological gambling is linked to reduced activation of the mesolimbic reward system. Nat. Neurosci. 8 (2005) 147-148
156. Reynolds B. A review of delay-discounting research with humans: relations to drug use and gambling. Behav. Pharmacol. 17 (2006) 651-667
157. Riccio C.A., and French C.L. The status of empirical support for treatments of attention deficits. Clin. Neuropsychol. 18 (2004) 528-558
158. Risinger R.C., Salmeron B.J., Ross T.J., Amen S.L., Sanfilipo M., Hoffmann R.G., Bloom A.S., Garavan H., and Stein E.A. Neural correlates of high and craving during cocaine self-administration using BOLD fMRI. Neuroimage 26 (2005) 1097-1108
159. Robbins S.J., and Ehrman R.N. The role of attentional bias in substance abuse. Behav. Cogn. Neurosci. Rev. 3 (2004) 243-260
160. Roberts K.L., and Hall D.A. Examining a supramodal network for conflict processing: a systematic review and novel functional magnetic resonance imaging data for related visual and auditory Stroop tasks. J. Cogn. Neurosci. 20 6 (2008) 1063-1078
161. Robinson T.E., and Berridge K.C. Review. The incentive sensitization theory of addiction: some current issues. Philos. Trans. R. Soc. Lond. B: Biol. Sci. 363 1507 (2008) 3137-3146
162. Roca M., Torralva T., Lopez P., Cetkovich M., Clark L., and Manes F. Executive functions in pathologic gamblers selected in an ecologic setting. Cogn. Behav. Neurol. 21 (2008) 1-4
163. Rodriguez-Jimenez R., Avila C., Jimenez-Arriero M.A., Ponce G., Monasor R., Jimenez M., Aragues M., Hoenicka J., Rubio G., and Palomo T. Impulsivity and sustained attention in pathological gamblers: influence of childhood ADHD history. J. Gambl. Stud. 22 (2006) 451-461
164. Rogers R.D., Owen A.M., Middleton H.C., Williams E.J., Pickard J.D., Sahakian B.J., and Robbins T.W. Choosing between small, likely rewards and large, unlikely rewards activates inferior and orbital prefrontal cortex. J. Neurosci. 19 (1999) 9029-9038
165. Rolls E.T. The functions of the orbitofrontal cortex. Brain Cogn. 55 (2004) 11-29
166. Rosner S., Leucht S., Lehert P., and Soyka M. Acamprosate supports abstinence, naltrexone prevents excessive drinking: evidence from a meta-analysis with unreported outcomes. J. Psychopharmacol. 22 (2008) 11-23
167. Rugle L., and Melamed L. Neuropsychological assessment of attention problems in pathological gamblers. J. Nerv. Ment. Dis. 181 (1993) 107-112
168. Shalev L., Tsal Y., and Mevorach C. Computerized progressive attentional training (CPAT) program: effective direct intervention for children with ADHD. Child Neuropsychol. 13 (2007) 382-388
169. Sharpe L. A reformulated cognitive-behavioral model of problem gambling. A biopsychosocial perspective. Clin. Psychol. Rev. 22 (2002) 1-25
170. Steeves T.D., Miyasaki J., Zurowski M., Lang A.E., Pellecchia G., Van E.T., Rusjan P., Houle S., and Strafella A.P. Increased striatal dopamine release in Parkinsonian patients with pathological gambling: a [11C] raclopride PET study. Brain 132 (2009) 1376-1385
171. Sutton R.S., and Barto A.G. Reinforcement learning: an introduction. IEEE Trans. Neural. Netw. 9 (1998) 1054
172. Sylvain C., Ladouceur R., and Boisvert J.M. Cognitive and behavioral treatment of pathological gambling: a controlled study. J. Consult. Clin. Psychol. 65 (1997) 727-732
173. Tamminga C.A., and Nestler E.J. Pathological gambling: focusing on the addiction, not the activity. Am. J. Psychiatry 163 (2006) 180-181
174. Tanabe J., Thompson L., Claus E., Dalwani M., Hutchison K., and Banich M.T. Prefrontal cortex activity is reduced in gambling and nongambling substance users during decision-making. Hum. Brain Mapp. 28 12 (2007) 1276-1286
175. Tapert S.F., Brown G.G., Baratta M.V., and Brown S.A. fMRI BOLD response to alcohol stimuli in alcohol dependent young women. Addict. Behav. 29 (2004) 33-50
176. Thanos P.K., Volkow N.D., Freimuth P., Umegaki H., Ikari H., Roth G., Ingram D.K., and Hitzemann R. Overexpression of dopamine D2 receptors reduces alcohol self-administration. J. Neurochem. 78 (2001) 1094-1103
177. Thiel A., Hilker R., Kessler J., Habedank B., Herholz K., and Heiss W.D. Activation of basal ganglia loops in idiopathic Parkinson's disease: a PET study. J. Neural. Transm. 110 (2003) 1289-1301
178. Tobler P.N., O'doherty J.P., Dolan R.J., and Schultz W. Reward value coding distinct from risk attitude-related uncertainty coding in human reward systems. J. Neurophysiol. 97 (2007) 1621-1632
179. Toneatto T., Blitz-Miller T., Calderwood K., Dragonetti R., and Tsanos A. Cognitive distortions in heavy gambling. J. Gambl. Stud. 13 (1997) 253-266
180. Torta D.M., and Castelli L. Reward pathways in Parkinson's disease: clinical and theoretical implications. Psychiatry Clin. Neurosci. 62 (2008) 203-213
181. Verdejo-Garcia A., and Bechara A. A somatic marker theory of addiction. Neuropharmacology 56 Suppl. 1 (2009) 48-62
182. Verdejo-Garcia A., Lawrence A.J., and Clark L. Impulsivity as a vulnerability marker for substance-use disorders: review of findings from high-risk research, problem gamblers and genetic association studies. Neurosci. Biobehav. Rev. 32 (2008) 777-810
183. Verdejo-Garcia A., Lopez-Torrecillas F., Gimenez C.O., and Perez-Garcia M. Clinical implications and methodological challenges in the study of the neuropsychological correlates of cannabis, stimulant, and opioid abuse. Neuropsychol. Rev. 14 (2004) 1-41
184. Vitaro F., Arseneault L., and Tremblay R.E. Impulsivity predicts problem gambling in low SES adolescent males. Addiction 94 (1999) 565-575
185. Volkow N.D., Fowler J.S., and Wang G.J. The addicted human brain viewed in the light of imaging studies: brain circuits and treatment strategies. Neuropharmacology 47 Suppl. 1 (2004) 3-13
186. Volkow N.D., Fowler J.S., Wang G.J., Baler R., and Telang F. Imaging dopamine's role in drug abuse and addiction. Neuropharmacology 56 Suppl. 1 (2008) 3-8
187. Volkow N.D., Fowler J.S., Wang G.J., and Goldstein R.Z. Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies. Neurobiol. Learn. Mem. 78 (2002) 610-624
188. Volkow N.D., Wang G.J., Telang F., Fowler J.S., Logan J., Childress A.R., Jayne M., Ma Y., and Wong C. Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction. J. Neurosci. 26 (2006) 6583-6588
189. Vorel S.R., Liu X., Hayes R.J., Spector J.A., and Gardner E.L. Relapse to cocaine-seeking after hippocampal theta burst stimulation. Science 292 (2001) 1175-1178
190. Wager T.D., Sylvester C.Y., Lacey S.C., Nee D.E., Franklin M., and Jonides J. Common and unique components of response inhibition revealed by fMRI. Neuroimage 27 (2005) 323-340
191. Wang Z., Faith M., Patterson F., Tang K., Kerrin K., Wileyto E.P., Detre J.A., and Lerman C. Neural substrates of abstinence-induced cigarette cravings in chronic smokers. J. Neurosci. 27 (2007) 14035-14040
192. Wiers R.W., Cox W.M., Field M., Fadardi J.S., Palfai T.P., Schoenmakers T., and Stacy A.W. The search for new ways to change implicit alcohol-related cognitions in heavy drinkers. Alcohol. Clin. Exp. Res. 30 (2006) 320-331
193. Wilson S.J., Sayette M.A., and Fiez J.A. Prefrontal responses to drug cues: a neurocognitive analysis. Nat. Neurosci. 7 (2004) 211-214
194. Wrase J., Grusser S.M., Klein S., Diener C., Hermann D., Flor H., Mann K., Braus D.F., and Heinz A. Development of alcohol-associated cues and cue-induced brain activation in alcoholics. Eur. Psychiatry 17 (2002) 287-291
195. Wrase J., Kahnt T., Schlagenhauf F., Beck A., Cohen M.X., Knutson B., and Heinz A. Different neural systems adjust motor behavior in response to reward and punishment. Neuroimage 36 (2007) 1253-1262
196. Wrase J., Schlagenhauf F., Kienast T., Wustenberg T., Bermpohl F., Kahnt T., Beck A., Strohle A., Juckel G., Knutson B., and Heinz A. Dysfunction of reward processing correlates with alcohol craving in detoxified alcoholics. Neuroimage 35 (2007) 787-794
197. Wulfert E., Roland B.D., Hartley J., Wang N., and Franco C. Heart rate arousal and excitement in gambling: winners versus losers. Psychol. Addict. Behav. 19 (2005) 311-316
198. Yacubian J., Glascher J., Schroeder K., Sommer T., Braus D.F., and Buchel C. Dissociable systems for gain- and loss-related value predictions and errors of prediction in the human brain. J. Neurosci. 26 (2006) 9530-9537
199. Yacubian J., Sommer T., Schroeder K., Glascher J., Braus D.F., and Buchel C. Subregions of the ventral striatum show preferential coding of reward magnitude and probability. Neuroimage 38 (2007) 557-563
200. Yechiam E., Busemeyer J.R., Stout J.C., and Bechara A. Using cognitive models to map relations between neuropsychological disorders and human decision-making deficits. Psychol. Sci. 16 (2005) 973-978
201. Zack M., and Poulos C.X. Effects of the atypical stimulant modafinil on a brief gambling episode in pathological gamblers with high vs. low impulsivity. J. Psychopharmacol. 23 6 (2009) 660-671
202. Zack M., and Poulos C.X. A D2 antagonist enhances the rewarding and priming effects of a gambling episode in pathological gamblers. Neuropsychopharmacology 32 (2007) 1678-1686
203. Zack M., and Poulos C.X. Amphetamine primes motivation to gamble and gambling-related semantic networks in problem gamblers. Neuropsychopharmacology 29 (2004) 195-207
204. Zorko M., Marusic A., Cebasek-Travnik Z., and Bucik V. The frontal lobe hypothesis: impairment of executive cognitive functions in chronic alcohol in-patients. Psychiatr. Danub. 16 (2004) 21-28
205. Zuckerman M., Eysenck S., and Eysenck H.J. Sensation seeking in England and America: cross-cultural, age, and sex comparisons. J. Consult. Clin. Psychol. 46 (1978) 139-149