Structure-based stability analysis of an extremely stable dimeric DNA binding protein from Sulfolobus islandicus

Biochemistry

Volumn 48, Issue 42, 2009, Pages 10030-10037

  Weininger, Ulrich ^a   Zeeb, Markus ^b,c   Neumann, Piotr ^a   L̈ow, Christian ^a,d   Stubbs, Milton T ^a   Lipps, Georg ^b,e   Balbach, Jochen ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF BAYREUTH   (Germany)

^c BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^d KAROLINSKA INSTITUTE   (Sweden)

^e UNIVERSITY OF APPLIED SCIENCES AND ARTS NORTHWESTERN SWITZERLAND   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACCESSIBLE SURFACE AREAS; ARCHAEON; COPY NUMBER; DIMERIC PROTEINS; DNA BINDING; DNA-BINDING PROTEIN; DOUBLE STRANDED DNA; GENE REGULATIONS; GIBBS FREE ENERGY CHANGES; H-D EXCHANGE; HOMODIMERS; HYPERTHERMOPHILIC ORGANISMS; INTERMOLECULAR BINDING; LOCAL FLUCTUATIONS; MESOPHILIC; NMR TITRATION; RIBBON-HELIX-HELIX FOLD; SOLUTION NMR; STABILITY ANALYSIS; STRUCTURE-BASED; SURFACE AREA;

BINDING SITES; CRYSTAL STRUCTURE; DIMERS; DNA; GENES; HYDROPHOBICITY; NUCLEAR MAGNETIC RESONANCE; NUCLEIC ACIDS; THERMODYNAMIC STABILITY; TITRATION;

BINDING ENERGY;

DNA BINDING PROTEIN; DOUBLE STRANDED DNA; HOMODIMER; MONOMER;

ARTICLE; BETA SHEET; BINDING SITE; CRYSTAL STRUCTURE; DNA BINDING; ENERGY; GENE INTERACTION; HYDROPHOBICITY; HYPERTHERMOPHILIC ARCHAEON; MESOPHILIC BACTERIUM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN STABILITY; PROTEIN STRUCTURE; SULFOLOBUS; THERMODYNAMICS;

AMINO ACID SEQUENCE; ARCHAEAL PROTEINS; BINDING SITES; DIMERIZATION; DNA; DNA-BINDING PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP; SULFOLOBUS; THERMODYNAMICS;

ARCHAEA; SULFOLOBUS ISLANDICUS;

EID: 70350214644     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900760n     Document Type: Article

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