Promoter switch: A novel mechanism causing biallelic PEG1/MEST expression in invasive breast cancer

Human Molecular Genetics

Volumn 11, Issue 12, 2002, Pages

  Cifuentes Diaz, Carmen ^a   Nicole, Sophie ^a   Velasco, Maria E ^a   Borra Cebrian, Christophe ^a   Panozzo, Cristina ^a   Frugier, Tony ^a   Millet, Gaelle ^a   Roblot, Natacha ^a   Joshi, Vandana ^a   Melki, Judith ^a  

^a UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR; PROTEIN MEST; PROTEIN PEG1; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ALLELE; ARTICLE; BREAST CARCINOMA; CANCER INVASION; COLON CANCER; CONTROLLED STUDY; GENE EXPRESSION; GENE SWITCHING; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; GENOME IMPRINTING; HUMAN; HUMAN TISSUE; LUNG ADENOCARCINOMA; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BREAST NEOPLASMS; DNA PRIMERS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; HUMANS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); PROTEIN ISOFORMS; PROTEINS;

EID: 70350187040     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

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2. Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour
3. Biallelic expression of the IGF2 gene in human breast disease
4. Imprinting and expression of insulin-like growth factor II and H19 in normal breast tissue and breast tumour
5. Relaxation of imprinting in human insulin-like growth factor II gene, IGF2, in sporadic breast carcinomas
6. Reversal of loss of imprinting in tumour cells by 5-aza-2′-deoxycytidine
7. Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability
8. Multipoint imprinting analysis in sporadic colorectal cancers with and without microsatellite instability
9. Frequent loss of imprinting of PEG1/MEST in invasive breast cancer
10. Isoform-specific imprinting of the human PEG1/MEST gene
11. The human GNAS1 gene is imprinted and encodes distinct paternally and biallelically expressed G proteins
12. Biderectional imprinting of a single gene: GNAS1 encodes maternally, paternally, and biallelically derived proteins
13. An imprinted antisense transcript at the human GNAS1 locus
14. γ2-COP, a novel imprinted gene on chromosome 7q32, defines a new imprinting cluster in the human genome
15. No evidence of PEG1/MEST gene mutations in Silver-Russell syndrome patients
16. Expression of the imprinted genes MEST/Mest in human and murine placenta suggests a role in angiogenesis
17. Human PEG1/MEST, an imprinted gene on chromosome 7
18. Frequent loss of imprinting of IGF2 and MEST in lung adenocarcinoma