The impact of pancreas and kidney transplant on cardiovascular risk factors (analyzed by mode of immunosuppression and exocrine drainage)

Clinical Transplantation

Volumn 23, Issue 5, 2009, Pages 616-620

  Davenport, Colin ^a   Hamid, Nadira ^a   O'Sullivan, Eoin P ^a   Daly, Padraig ^a   Mohan, Ponnusamy ^a   Little, Dilly ^a   Thompson, Christopher J ^a   Agha, Amar ^a   Hickey, David ^a   Smith, Diarmuid ^a  

^a DUBLIN CITY COUNCIL   (Ireland)

Author keywords

Cardiovascular; SPK; Transplant

Indexed keywords

ANTIHYPERTENSIVE AGENT; AZATHIOPRINE; CORTICOSTEROID; CYCLOSPORIN; HEMOGLOBIN A1C; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; TACROLIMUS; THYMOCYTE ANTIBODY;

ADULT; ARTICLE; BODY WEIGHT; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIASTOLIC BLOOD PRESSURE; FEMALE; GLYCEMIC CONTROL; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INSULIN DEPENDENT DIABETES MELLITUS; IRELAND; KIDNEY FAILURE; KIDNEY PANCREAS TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SURGICAL DRAINAGE; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; BLOOD GLUCOSE; CARDIOVASCULAR DISEASES; CHOLESTEROL; CYCLOSPORINE; DIABETES MELLITUS, TYPE 1; DRAINAGE; FEMALE; GRAFT REJECTION; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; MALE; MYCOPHENOLIC ACID; PANCREAS TRANSPLANTATION; POSTOPERATIVE COMPLICATIONS; PROGNOSIS; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE; TACROLIMUS; TREATMENT OUTCOME; TRIGLYCERIDES;

EID: 70350170241     PISSN: 09020063     EISSN: 13990012     Source Type: Journal    
DOI: 10.1111/j.1399-0012.2009.01066.x     Document Type: Article

References (19)

1. Reddy KS, Stablein D, Taranto S. Long-term survival following simultaneous kidney-pancreas transplantation versus kidney transplantation alone in patients with type 1 diabetes mellitus and renal failure. Am J Kidney Dis 2003, 41:464.
2. Ojo AO, Meier-Kriesche HU, Hanson JA. The impact of simultaneous pancreas-kidney transplantation on long-term patient survival. Transplantation 2001, 71:82.
3. Mohan P, Safi K, Little DM. Improved patient survival in recipients of simultaneous pancreas-kidney transplant compared with kidney transplant alone in patients with type 1 diabetes mellitus and end-stage renal disease. Br J Surg 2003, 90:1137.
4. Smets YF, Westendorp RG, van der Pijl JW. Effect of simultaneous pancreas-kidney transplantation on mortality of patients with type-1 DM and end-stage renal failure. Lancet 1999, 353:1915.
5. Coppelli A, Giannarelli R, Mariotti R. Pancreas transplant alone determines early improvement of cardiovascular risk factors and cardiac function in type 1 diabetic patients. Transplantation 2003, 76:974.
6. Hricik D, Chareandee C, Knauss T. Hypertension after kidney-pancreas transplantation: role of bladder versus enteric pancreatic drainage. Transplantation 2000, 70:494.
7. Hughes TA, Gaber AO, Amiri HS. Kidney-pancreas transplantation. The effect of portal versus systemic venous drainage of the pancreas on the lipoprotein composition. Transplantation 1995, 60:1406.
8. Tamajon LP, Miranda DM, Figueroa AC. Improved cardiovascular risk profile of patients with type 1 diabetes mellitus and renal failure after simultaneous pancreas-kidney transplantation. Transplant Proc 2005, 37:3979.
9. Larsen J, Larson C, Hirst K. Lipid status after combined pancreas-kidney transplantation and kidney transplantation alone in type I diabetes mellitus. Transplantation 1992, 54:992.
10. Larsen JL, Stratta RJ, Miller S. Lipid status improves following combined pancreas kidney transplantation. Diabetes Care 1992, 15:35.
11. La Rocca E, Secchi A, Parlavecchia M. Lipoprotein profile after combined kidney-pancreas transplantation in insulin dependent diabetes mellitus. Transpl Int 1995, 8:190.
12. Purnell JQ, Marcovina SM, Hokanson JE. Levels of lipoprotein (a), apolipoprotein B, and lipoprotein cholesterol distribution in IDDM: results from follow-up in the Diabetes Control and Complications Trial. Diabetes 1995, 44:1218.
13. Secchi A, Malaise J, Caldara R. Metabolic results 3 years after simultaneous pancreas-kidney transplantation. Nephrol Dial Transplant 2005, 20(Suppl 2):ii18. ii62
14. Stratta RJ, Taylor RJ, Zorn BH. Combined pancreas-kidney transplantation: preliminary results and metabolic effects. Am J Gastroenterol 1991, 86:697.
15. Lo A, Stratta RJ, Hathaway DK. Long-term outcomes in simultaneous kidney-pancreas transplant recipients with portal-enteric versus systemic bladder drainage. Am J Kidney Dis 2001, 38:132.
16. Elliott M, Kapoor A, Parker M. Improvement in hypertension in patients with diabetes mellitus after kidney/pancreas transplantation. Circulation 2001, 104:563.
17. Textor SC, Wiesner R, Wilson DJ. Systemic and renal hemodynamic differences between FK506 and cyclosporine in liver transplant recipients. Transplantation 1993, 55:1332.
18. Morales JM, Andres A, Rengel M. Influence of cyclosporin, tacrolimus and rapamycin on renal function and arterial hypertension after renal transplantation. Nephrol Dial Transplant 2001, 16(Suppl 1):121.
19. Copley JB, Staffeld C, Lindberg J. Cyclosporine to tacrolimus: effect on hypertension and lipid profiles in renal allografts. Transplant Proc 1998, 30:1254.