Generalized leukaemia cutis from a small cell variant of T-cell prolymphocytic leukaemia presenting with exfoliative dermatitis

Acta Dermato-Venereologica

Volumn 89, Issue 5, 2009, Pages 509-512

  Jeong, Ki Heon ^a   Lew, Bark Lynn ^a   Sim, Woo Young ^a  

^a Kyung Hee University Hospital   (South Korea)

Author keywords

Exfoliative dermatitis; Leukemia cutis; T cell prolymphocytic leukemia

Indexed keywords

CD2 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD5 ANTIGEN; CD7 ANTIGEN; CD8 ANTIGEN; FLUDARABINE PHOSPHATE; PREDNISONE;

AGED; ARTICLE; BLOOD EXAMINATION; BONE MARROW BIOPSY; CASE REPORT; CHROMOSOME ANALYSIS; EXFOLIATIVE DERMATITIS; FLOW CYTOMETRY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKEMIA; LEUKEMIA CELL; LYMPHOCYTIC INFILTRATION; MALE; PRIORITY JOURNAL; PROLYMPHOCYTIC LEUKEMIA; SKIN BIOPSY; SKIN LEUKEMIA; SKIN MANIFESTATION; T CELL PROLYMPHOCYTIC LEUKEMIA;

AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BIOPSY; BONE MARROW EXAMINATION; DERMATITIS, EXFOLIATIVE; DIAGNOSTIC ERRORS; ERYTHEMA; FATAL OUTCOME; HUMANS; IMMUNOPHENOTYPING; LEUKEMIA, PROLYMPHOCYTIC, T-CELL; LEUKEMIC INFILTRATION; MALE; PREDNISONE; SKIN; T-LYMPHOCYTES; TREATMENT FAILURE; VIDARABINE;

EID: 70350150026     PISSN: 00015555     EISSN: None     Source Type: Journal    
DOI: 10.2340/00015555-0672     Document Type: Article

References (12)

1. Catovsky D, Ralfkiaer E, Muller-Hermelink HK. T-cell prolymphocytic leukaemia. In: Jaffe ES, Harris NL, Stein H, Vardiman JW, editors. Pathology and genetics of tumours of haematopoietic and lymphoid tissues. World Health Organization Classification of Tumours. Lyon, France: IARC Press, 2001: p. 195-198.
2. Matutes E, Brito-Babapulle V, Swansbury J, Ellis J, Morilla R, Dearden C, et al. Clinical and laboratory features of 78 cases of T-prolymphocytic leukemia. Blood 1991; 78: 3269-3274.
3. Thorat KB, Gujral S, Kumar A, Nair CN. Small cell variant of T-cell prolymphocytic leukemia exhibiting suppressor phenotype. Leuk Lymphoma 2006; 47: 1711-1713. (Pubitemid 44364050)
4. Keating MJ, Cazin B, Coutré S, Birhiray R, Kovacsovics T, Langer W, et al. Campath-1H treatment of T-cell prolymphocytic leukemia in patients for whom at least one prior chemotherapy regimen has failed. J Clin Oncol 2002; 20: 205-213. (Pubitemid 34032613)
5. Foucar K. Mature T-cell leukemias including T-prolymphocytic leukemia, adult T-cell leukemia/lymphoma, and Sézary syndrome. Am J Clin Pathol 2007; 127: 496-510. (Pubitemid 46587464)
6. Herling M, Khoury JD, Washington LT, Duvic M, Keating MJ, Jones D. A systematic approach to diagnosis of mature T-cell leukemias reveals heterogeneity among WHO categories. Blood 2004; 104: 328-335. (Pubitemid 38900011)
7. Robak E, Robak T. Skin lesions in chronic lymphocytic leukemia. Leuk Lymphoma 2007; 48: 855-865. (Pubitemid 47161555)
8. Miyoshi I, Uemura Y, Sonobe H, Taguchi H. Leukemia cutis. Intern Med 2007; 46: 65-66.
9. Watson KM, Mufti G, Salisbury JR, du Vivier AW, Creamer D. Spectrum of clinical presentation, treatment and prognosis in a series of eight patients with leukaemia cutis. Clin Exp Dermatol 2006; 31: 218-221.
10. Mallett RB, Matutes E, Catovsky D, Maclennan K, Mortimer PS, Holden CA. Cutaneous infiltration in T-cell prolymphocytic leukaemia. Br J Dermatol 1995; 132: 263-266.
11. Magro CM, Morrison CD, Heerema N, Porcu P, Sroa N, Deng AC. T-cell prolymphocytic leukemia: an aggressive T-cell malignancy with frequent cutaneous tropism. J Am Acad Dermatol 2006; 55: 467-477. (Pubitemid 44209286)
12. Volk JR, Kjeldsberg CR, Eyre HJ, Marty J. T-cell prolymphocytic leukemia. Clinical and immunology characterization. Cancer 1983; 52: 2049-2054.