Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 40, 2009, Pages 17019-17024

  Van Anken, Eelco ^a,f   Pena, Florentina ^a   Hafkemeijer, Nicole ^a,g   Christis, Chantal ^a,h   Romijn, Edwin P ^a,i   Grauschopf, Ulla ^b,j   Oorschot, Viola M J ^c   Pertel, Thomas ^d,e   Engels, Sander ^a   Ora, Ari ^a,k   Lástun, Viorica ^a   Glockshuber, Rudi ^b   Klumperman, Judith ^c   Heck, Albert J R ^a   Luban, Jeremy ^d,e   Braakman, Ineke ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d UNIVERSITY OF GENEVA   (Switzerland)

^e INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Switzerland)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g CrossBeta (BV)   (Netherlands)

^h MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

ⁱ PHILIPS RESEARCH LABORATORIES   (Netherlands)

^j F HOFFMANN LA ROCHE LTD   (Switzerland)

^k UNIVERSITY OF HELSINKI   (Finland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CYSTEINE DERIVATIVE; DISULFIDE; ENDOPLASMIC RETICULUM PROTEIN 1; GLUCOSE REGULATED PROTEIN 78; IMMUNOGLOBULIN M; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; CONTROLLED STUDY; DISULFIDE BOND; ENZYME ACTIVITY; FEMALE; HEAVY CHAIN; HUMAN; HUMAN CELL; IMMUNOGLOBULIN PRODUCTION; LIGHT CHAIN; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; STEADY STATE;

AMINO ACID SEQUENCE; ANIMALS; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINE, TUMOR; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENDOPLASMIC RETICULUM; HEAT-SHOCK PROTEINS; HELA CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOGLOBULIN M; MASS SPECTROMETRY; MICE; MICROSCOPY, FLUORESCENCE; MICROSCOPY, IMMUNOELECTRON; MOLECULAR CHAPERONES; OXIDOREDUCTASES; PLASMA CELLS; RNA INTERFERENCE; SULFHYDRYL COMPOUNDS;

EID: 70350130802     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0903036106     Document Type: Article

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