Improvement of facial skin characteristics using copper oxide containing pillowcases: A double-blind, placebo-controlled, parallel, randomized study

International Journal of Cosmetic Science

Volumn 31, Issue 6, 2009, Pages 437-443

  Borkow, G ^a   Gabbay, J ^a   Lyakhovitsky, A ^b   Huszar, M ^c  

^a Cupron Inc   (Israel)

^b SHEBA MEDICAL CENTER   (Israel)

^c KAPLAN MEDICAL CENTER   (Israel)

Author keywords

Clinical study; Copper oxide; Pillowcases; Textile; Wrinkles

Indexed keywords

COPPER OXIDE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; REGENERATION; SKIN; SKIN ABSORPTION; SLEEP; WRINKLE;

ADMINISTRATION, CUTANEOUS; ADULT; BEDDING AND LINENS; COPPER; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MIDDLE AGED; SKIN AGING; STATISTICS, NONPARAMETRIC; SURFACE PROPERTIES;

EID: 70350126212     PISSN: 01425463     EISSN: 14682494     Source Type: Journal    
DOI: 10.1111/j.1468-2494.2009.00515.x     Document Type: Article

References (26)

1. Uauy, R., Olivares, M. Gonzalez, M. Essentiality of copper in humans. Am. J. Clin. Nutr. 67, 952S 959S (1998).
2. Pickart, L. The human tri-peptide GHK and tissue remodeling. J. Biomater. Sci. Polym. Ed. 19, 969 988 (2008).
3. Szauter, K.M., Cao, T., Boyd, C.D. Csiszar, K. Lysyl oxidase in development, aging and pathologies of the skin. Pathol. Biol. (Paris) 53, 448 456 (2005).
4. Borkow, G., Gabbay, J. Zatcoff, R.C. Could chronic wounds not heal due to too low local copper levels? Med. Hypotheses 70, 610 613 (2008).
5. Trumbo, P., Yates, A.A., Schlicker, S. Poos, M. Dietary reference intakes: vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. J. Am. Diet. Assoc. 101, 294 301 (2001).
6. O'Brien, P.A., Kulier, R., Helmerhorst, F.M., Usher-Patel, M. d'Arcangues, C. Copper-containing, framed intrauterine devices for contraception: a systematic review of randomized controlled trials. Contraception 77, 318 327 (2008).
7. Pereira, C.E. Felcman, J. Correlation between five minerals and the healing effect of Brazilian medicinal plants. Biol. Trace Elem. Res. 65, 251 259 (1998).
8. Schlemm, D.J., Crowe, M.J., McNeill, R.B., Stanley, A.E. Keller, S.J. Medicinal yeast extracts. Cell Stress Chaperones 4, 171 176 (1999).
9. Hostynek, J.J. Maibach, H.I. Copper hypersensitivity: dermatologic aspects: an overview. Rev. Environ. Health 18, 153 183 (2003).
10. Gorter, R.W., Butorac, M. Cobian, E.P. Examination of the cutaneous absorption of copper after the use of copper-containing ointments. Am. J. Ther. 11, 453 458 (2004).
11. Hostynek, J.J., Dreher, F. Maibach, H.I. Human stratum corneum penetration by copper: in vivo study after occlusive and semi-occlusive application of the metal as powder. Food Chem. Toxicol. 44, 1539 1543 (2006).
12. Borkow, G. Gabbay, J. Putting copper into action: copper-impregnated products with potent biocidal activities. FASEB J. 18, 1728 1730 (2004).
13. Gabbay, J., Mishal, J., Magen, E., Zatcoff, R.C., Shemer-Avni, Y. Borkow, G. Copper oxide impregnated textiles with potent biocidal activities. J. Ind. Text. 35, 323 335 (2006).
14. Zatcoff, R.C., Smith, M.S. Borkow, G. Treatment of tinea pedis with socks containing copper impregnated fibers. Foot 18, 136 141 (2008).
15. Lindqvist, C., Tveten, S., Bondevik, B.E. Fagrell, D. A randomized, evaluator-blind, multicenter comparison of the efficacy and tolerability of Perlane versus Zyplast in the correction of nasolabial folds. Plast. Reconstr. Surg. 115, 282 289 (2005).
16. Narins, R.S., Brandt, F., Leyden, J., Lorenc, Z.P., Rubin, M. Smith, S. A randomized, double-blind, multicenter comparison of the efficacy and tolerability of Restylane versus Zyplast for the correction of nasolabial folds. Dermatol. Surg. 29, 588 595 (2003).
17. Fogelgren, B., Polgar, N., Szauter, K.M., Ujfaludi, Z., Laczko, R., Fong, K.S. Csiszar, K. Cellular fibronectin binds to lysyl oxidase with high affinity and is critical for its proteolytic activation. J. Biol. Chem. 280, 24690 24697 (2005).
18. Rucker, R.B., Kosonen, T., Clegg, M.S., Mitchell, A.E., Rucker, B.R., Uriu-Hare, J.Y. Keen, C.L. Copper, lysyl oxidase, and extracellular matrix protein cross-linking. Am. J. Clin. Nutr. 67, 996S 1002S (1998).
19. Peltonen, L., Kuivaniemi, H., Palotie, A., Horn, N., Kaitila, I. Kivirikko, K.I. Alterations in copper and collagen metabolism in the Menkes syndrome and a new subtype of the Ehlers-Danlos syndrome. Biochemistry 22, 6156 6163 (1983).
20. Royce, P.M., Camakaris, J. Danks, D.M. Reduced lysyl oxidase activity in skin fibroblasts from patients with Menkes' syndrome. Biochem. J. 192, 579 586 (1980).
21. Kobayashi, T., Saito, N., Takemori, N., Iizuka, S., Suzuki, K., Taniguchi, N. Iizuka, H. Ultrastructural localization of superoxide dismutase in human skin. Acta Derm. Venereol. 73, 41 45 (1993). (Pubitemid 23071344)
22. Ahmed, Z., Idowu, B.D. Brown, R.A. Stabilization of fibronectin mats with micromolar concentrations of copper. Biomaterials 20, 201 209 (1999).
23. Ahmed, Z., Briden, A., Hall, S. Brown, R.A. Stabilisation of cables of fibronectin with micromolar concentrations of copper: in vitro cell substrate properties. Biomaterials 25, 803 812 (2004).
24. Sajithlal, G.B., Chithra, P. Chandrakasan, G. An in vitro study on the role of metal catalyzed oxidation in glycation and crosslinking of collagen. Mol. Cell. Biochem. 194, 257 263 (1999).
25. Tenaud, I., Sainte-Marie, I., Jumbou, O., Litoux, P. Dreno, B. In vitro modulation of keratinocyte wound healing integrins by zinc, copper and manganese. Br. J. Dermatol. 140, 26 34 (1999).
26. Sen, C.K., Khanna, S., Venojarvi, M., Trikha, P., Ellison, E.C., Hunt, T.K. Roy, S. Copper-induced vascular endothelial growth factor expression and wound healing. Am. J. Physiol. Heart Circ. Physiol. 282, H1821 H1827 (2002).