Acute hypoxia impairs dynamic cerebral autoregulation: Results from two independent techniques

Journal of Applied Physiology

Volumn 107, Issue 4, 2009, Pages 1165-1171

  Subudhi, Andrew W ^a,b   Panerai, Ronney B ^c   Roach, Robert C ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Acute mountain sickness; Altitude; Cerebral blood flow; Transcranial Doppler

Indexed keywords

ACUTE DISEASE; ADULT; ARTERIAL PRESSURE; ARTERY BLOOD FLOW; ARTICLE; AUTOREGULATION; BREATHING; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HUMAN; HYPOXIA; MALE; MIDDLE CEREBRAL ARTERY; PRIORITY JOURNAL; SCORING SYSTEM; SYMPATHETIC TONE;

ACUTE DISEASE; ADULT; ANOXIA; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CARBON DIOXIDE; CEREBROVASCULAR CIRCULATION; FEMALE; FOURIER ANALYSIS; HEART RATE; HOMEOSTASIS; HUMANS; MALE; MANOMETRY; MIDDLE CEREBRAL ARTERY; MODELS, CARDIOVASCULAR; OXYGEN; PREDICTIVE VALUE OF TESTS; RADIAL ARTERY; RECOVERY OF FUNCTION; SEVERITY OF ILLNESS INDEX; SINGLE-BLIND METHOD; TIME FACTORS; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL; YOUNG ADULT;

EID: 70350118847     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00498.2009     Document Type: Article

References (38)

1. Aaslid R, Lindegaard KF, Sorteberg W, Nornes H. Cerebral autoregulation dynamics in humans. Stroke 20: 45-52, 1989.
2. Ainslie PN, Celi L, McGrattan K, Peebles K, Ogoh S. Dynamic cerebral autoregulation and baroreflex sensitivity during modest and severe step changes in arterial PCO2. Brain Res 1230: 115-124, 2008.
3. Ainslie PN, Ogoh S, Burgess K, Celi L, McGrattan K, Peebles K, Murrell C, Subedi P, Burgess KR. Differential effects of acute hypoxia and high altitude on cerebral blood flow velocity and dynamic cerebral autoregulation: alterations with hyperoxia. J Appl Physiol 104: 490-498, 2008. (Pubitemid 351232953)
4. Birch AA, Dirnhuber MJ, Hartley-Davies R, Iannotti F, Neil-Dwyer G. Assessment of autoregulation by means of periodic changes in blood pressure. Stroke 26: 834-837, 1995.
5. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1: 307-310, 1986. (Pubitemid 16134762)
6. Brodie FG, Atkins ER, Robinson TG, Panerai RB. Reliability of dynamic cerebral autoregulation measurement using spontaneous fluctuations in blood pressure. Clin Sci 116: 513-520, 2009.
7. Dawson SL, Blake MJ, Panerai RB, Potter JF. Dynamic but not static cerebral autoregulation is impaired in acute ischaemic stroke. Cerebrovasc Dis 10: 126-132, 2000.
8. Dawson SL, Panerai RB, Potter JF. Serial changes in static and dynamic cerebral autoregulation after acute ischaemic stroke. Cerebrovasc Dis 16: 69-75, 2003.
9. Easton PA, Slykerman LJ, Anthonisen NR. Ventilatory response to sustained hypoxia in normal adults. J Appl Physiol 61: 906-911, 1986. (Pubitemid 16033336)
10. O2. Am J Physiol Regul Integr Comp Physiol 287: R627-R632, 2004.
11. Giller CA. The frequency-dependent behavior of cerebral autoregulation. Neurosurgery 27: 362-368, 1990.
12. Hansen J, Sander M. Sympathetic neural overactivity in healthy humans after prolonged exposure to hypobaric hypoxia. J Physiol 546: 921-929, 2003. (Pubitemid 36204524)
13. Haubrich C, Kruska W, Diehl RR, Moller-Hartmann W, Klotzsch C. Dynamic autoregulation testing in patients with middle cerebral artery stenosis. Stroke 34: 1881-1885, 2003.
14. Haubrich C, Wendt A, Diehl RR, Klotzsch C. Dynamic autoregulation testing in the posterior cerebral artery. Stroke 35: 848-852, 2004. (Pubitemid 38419790)
15. Hlatky R, Furuya Y, Valadka AB, Gonzalez J, Chacko A, Mizutani Y, Contant CF, Robertson CS. Dynamic autoregulatory response after severe head injury. J Neurosurg 97: 1054-1061, 2002. (Pubitemid 35253541)
16. Hu HH, Kuo TB, Wong WJ, Luk YO, Chern CM, Hsu LC, Sheng WY. Transfer function analysis of cerebral hemodynamics in patients with carotid stenosis. J Cereb Blood Flow Metab 19: 460-465, 1999. (Pubitemid 30161234)
17. Hughson RL, Yamamoto Y, McCullough RE, Sutton JR, Reeves JT. Sympathetic and parasympathetic indicators of heart rate control at altitude studied by spectral analysis. J Appl Physiol 77: 2537-2542, 1994.
18. Iwasaki K, Ogawa Y, Shibata S, Aoki K. Acute exposure to normobaric mild hypoxia alters dynamic relationships between blood pressure and cerebral blood flow at very low frequency. J Cereb Blood Flow Metab 27: 776-784, 2007. (Pubitemid 46474615)
19. Kemmotsu O, Ueda M, Otsuka H, Yamamura T, Okamura A, Ishikawa T, Winter DC, Eckerle JS. Blood pressure measurement by arterial tonometry in controlled hypotension. Anesth Analg 73: 54-58, 1991.
20. Lassen NA, Harper AM. Letter: High-altitude cerebral oedema. Lancet 2: 1154, 1975.
21. Mahony PJ, Panerai RB, Deverson ST, Hayes PD, Evans DH. Assessment of the thigh cuff technique for measurement of dynamic cerebral autoregulation. Stroke 31: 476-480, 2000.
22. Newell DW, Aaslid R, Lam A, Mayberg TS, Winn HR. Comparison of flow and velocity during dynamic autoregulation testing in humans. Stroke 25: 793-797, 1994. (Pubitemid 24111325)
23. Normand H, Lemarchand E, Arbeille P, Quarck G, Vaida P, Duretete A, Denise P. Beat-to-beat agreement of noninvasive tonometric and intra-radial arterial blood pressure during microgravity and hypergravity generated by parabolic flights. Blood 12: 357-362, 2007. (Pubitemid 351339497)
24. Panerai RB. Cerebral autoregulation: from models to clinical applications. Cardiovasc Eng 8: 42-59, 2008.
25. Panerai RB. Transcranial Doppler for evaluation of cerebral autoregulation. Clin Auton Res 19: 197-211, 2009.
26. Panerai RB, Dawson SL, Eames PJ, Potter JF. Cerebral blood flow velocity response to induced and spontaneous sudden changes in arterial blood pressure. Am J Physiol Heart Circ Physiol 280: H2162-H2174, 2001. (Pubitemid 32433795)
27. Panerai RB, Deverson ST, Mahony P, Hayes P, Evans DH. Effects of CO2 on dynamic cerebral autoregulation measurement. Physiol Meas 20: 265-275, 1999. (Pubitemid 29399838)
28. Panerai RB, Kerins V, Fan L, Yeoman PM, Hope T, Evans DH. Association between dynamic cerebral autoregulation and mortality in severe head injury. Br J Neurosurg 18: 471-479, 2004. (Pubitemid 40076191)
29. Panerai RB, White RP, Markus HS, Evans DH. Grading of cerebral dynamic autoregulation from spontaneous fluctuations in arterial blood pressure. Stroke 29: 2341-2346, 1998. (Pubitemid 28511955)
30. Paulson OB, Strandgaard S, Edvinsson L. Cerebral autoregulation. Cerebrovasc Brain Metab Rev 2: 161-192, 1990.
31. Roach RC, Hackett PH. Frontiers of hypoxia research: acute mountain sickness. J Exp Biol 204: 3161-3170, 2001. (Pubitemid 34861358)
32. Robbins PA. Role of the peripheral chemoreflex in the early stages of ventilatory acclimatization to altitude. Respir Physiol Neurobiol 158: 237-242, 2007.
33. Serrador JM, Picot PA, Rutt BK, Shoemaker JK, Bondar RL. MRI measures of middle cerebral artery diameter in conscious humans during simulated orthostasis. Stroke 31: 1672-1678, 2000.
34. Tiecks FP, Lam AM, Aaslid R, Newell DW. Comparison of static and dynamic cerebral autoregulation measurements. Stroke 26: 1014-1019, 1995.
35. Van Beek AH, Claassen JA, Rikkert MG, Jansen RW. Cerebral autoregulation: an overview of current concepts and methodology with special focus on the elderly. J Cereb Blood Flow Metab 28: 1071-1085, 2008.
36. Weil JV, Zwillich CW. Assessment of ventilatory response to hypoxia: methods and interpretation. Chest 70: 124-128, 1976.
37. Zhang R, Zuckerman JH, Giller CA, Levine BD. Transfer function analysis of dynamic cerebral autoregulation in humans. Am J Physiol Heart Circ Physiol 274: H233-H241, 1998. (Pubitemid 28092587)
38. Zhang R, Zuckerman JH, Iwasaki K, Wilson TE, Crandall CG, Levine BD. Autonomic neural control of dynamic cerebral autoregulation in humans. Circulation 106: 1814-1820, 2002.