RNase R mutants elucidate the catalysis of structured RNA: RNA-binding domains select the RNAs targeted for degradation

Biochemical Journal

Volumn 423, Issue 2, 2009, Pages 291-301

  Matos, Rute Gonçalves ^a   Barbas, Ana ^a   Arraiano, Cecília Maria ^a  

^a INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

Author keywords

Exosome; Ribonuclease; RNA degradation; RNase II; RNase R; Structured RNA

Indexed keywords

EXOSOME; RIBONUCLEASE; RNASE II; RNASE R; STRUCTURED RNA;

DEGRADATION; NUCLEIC ACIDS; RNA; SUBSTRATES;

ENZYMES;

RIBONUCLEASE; RIBONUCLEASE II; RIBONUCLEASE R; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; BINDING AFFINITY; BINDING SITE; CODON; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; RNA ANALYSIS; RNA BINDING; RNA DEGRADATION; RNA METABOLISM; RNA PURIFICATION; RNA STRUCTURE;

BASE SEQUENCE; CATALYSIS; CATALYTIC DOMAIN; ESCHERICHIA COLI PROTEINS; EXORIBONUCLEASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RNA; RNA STABILITY; TYROSINE;

EUKARYOTA;

EID: 70350111321     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20090839     Document Type: Article

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