Fine specificity of autoantibodies induced by mouse hepatitis virus A59

Viral Immunology

Volumn 22, Issue 5, 2009, Pages 287-294

  Duhalde Vega, Maite ^a   Aparicio, José Luis ^a   Retegui, Lilia A ^a  

^a Instituto de Quimica y Fisicoquimica Biologicas Buenos Aires   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; EPITOPE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY SPECIFICITY; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CROSS REACTION; EPITOPE MAPPING; FEMALE; HEPATITIS VIRUS; HEPATITIS VIRUS A59; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODY SPECIFICITY; AUTOANTIBODIES; AUTOIMMUNE DISEASES; CORONAVIRUS INFECTIONS; EPITOPE MAPPING; FEMALE; HUMANS; HYDROLASES; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MURINE HEPATITIS VIRUS; SEQUENCE HOMOLOGY, AMINO ACID; VIRAL PROTEINS;

MURINE HEPATITIS VIRUS; MUS;

EID: 70350110895     PISSN: 08828245     EISSN: None     Source Type: Journal    
DOI: 10.1089/vim.2009.0019     Document Type: Article

References (20)

1. Blüthner M, Mahler M, Müller DB, Dünzi H, and Bautz FA: Identification of an a-helical epitope region on the PM=Scl- 100 autoantigen with structural homology to a region on the heterochromatin p25b autoantigen using immobilized overlapping synthetic peptides. J Mol Med 2000;78: 47-54.
2. Cohen AD, and Shoenfeld Y: The viral-autoimmunity relationship. Viral Immunol 1995;8:1-9.
3. Coutelier J-P, Coulie PG, Wauters P, Heremans H, and van der Logt JTM: In vivo polyclonal B-lymphocyte activation elicited by murine viruses. J Virol 1990;64:5383-5388.
4. Croxford JL, Olson J, and Miller SD: Epitope spreading and molecular mimicry as triggers of autoimmunity in the Theiler's virus induced demyelinating disease model of multiple sclerosis. Autoimmunity Rev 2002;1:251-260.
5. Duhalde-Vega M, Loureiro ME, Mathieu PA, and Retegui LA: The peptide specificities of the autoantibodies elicited by mouse hepatitis virus A59. J Autoimmunity 2006;27:203-209.
6. Farris AD, Keech CL, Gordon TP, and McCluskey J: Epitope mimics and determinant spreading: pathways to autoimmunity. Cell Mol Life Sci 2000;57:569-578.
7. Geysen HM, Rodda SJ, Mason TJ, Tribbick G, and Schoofs PG: Strategies for epitope analysis using peptide synthesis. J Immunol Methods 1987;102:259-274.
8. Godfraind C, Havaux N, Holmes KV, and Coutelier J-P: Role of virus receptor-bearing endothelial cells of the blood-brain barrier in preventing the spread of mouse hepatitis virus- A59 into the central nervous system. J NeuroVirology 1997; 3:428-434.
9. Kohm AP, Fuller KG, and Miller SD: Mimicking the way to autoimmunity: an evolving theory of sequence and structural homology. Trends Microbiol 2003;11:101-105.
10. Lawson CM: Evidence for mimicry by viral antigens in animal models of autoimmune disease including myocarditis. Cell Mol Life Sci 2000;57:552-560.
11. Liang B, and Mamula MJ: Molecular mimicry and the role of B lymphocytes in the processing of autoantigens. CMLS Cell Mol Life Sci 2000;57:561-568.
12. Mathieu PA, Gómez KA, Coutelier J-P, and Retegui LA: Identification of two liver proteins recognized by autoantibodies elicited in mice infected with mouse hepatitis virus A59. Eur J Immunol 2001;31:1447-1455.
13. Mathieu PA, Gómez KA, Coutelier J-P, and Retegui LA: Sequence similarity and structural homologies are involved in the autoimmune response elicited by mouse hepatitis virus A59. J Autoimmunity 2004;23:117-126.
14. Rose NR: The role of infection in the pathogenesis of autoimmune disease. Semin Immunol 1998;10:5-13.
15. Routsias JG, Tzioufas AG, and Moutsopoulos HM: The clinical value of intracellular autoantigens B-cell epitopes in systemic rheumatic diseases. Clin Chim Acta 2004;340: 1-25.
16. Routsias JG, Viachoyiannopoulos PG, and Tzioufas AG: Autoantibodies to intracellular autoantigens and their B-cell epitopes: Molecular probes to study the autoimmune response. Crit Rev Clin Lab Sci 2006;43:1-6.
17. Rubinstein ND, Mayrose I, Halperin D, Yekutieli D. Gershoni JM, and Pupko T: Computational characterization of B-cell epitopes. Mol Immunol 2008;45:3477-3489.
18. Scealy M, Mackay IR, and Rowley MJ: Amino acids critical for binding of autoantibody to an immunodominant conformational epitope of the pyruvate dehydrogenase complex subunit E2: Identification by phage display and site-directed mutagenesis. Mol Immunol 2006;43:745-753.
19. Timm DE, Mueller HA, Bhanumoorthy P, Harp P, and Bunick GJ: Crystal structure and mechanism of a carboncarbon bond hydrolase. Structure 1999;7:1023-1033.
20. Westall FC: Molecular mimicry or structural mimicry? Mol Immunol 2006;43:1062-1064.