Synthesis, characterization, cytotoxic activity and DNA binding Ni(II) complex with the 6-hydroxy chromone-3-carbaldehyde thiosemicarbazone

Journal of Organometallic Chemistry

Volumn 694, Issue 25, 2009, Pages 4069-4075

  Wang, Bao dui ^a   Yang, Zheng Yin ^a   Lü, Ming hua ^b   Hai, Jun ^b   Wang, Qin ^b   Chen, Zhong Ning ^c  

^a LANZHOU UNIVERSITY   (China)

^b LANZHOU UNIVERSITY   (China)

^c FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER   (China)

Author keywords

6 hydroxy chromone 3 carbaldehyde thiosemicarbazone; Crystal structure; Cytotoxic activity; DNA binding; Ni(II) complex

Indexed keywords

6-HYDROXY CHROMONE-3-CARBALDEHYDE THIOSEMICARBAZONE; BIOLOGICAL TESTS; CALF THYMUS DNA; CANCER CELL LINES; CHROMONES; CYTOTOXIC ACTIVITIES; CYTOTOXIC ACTIVITY; DNA BINDING; ETHIDIUM BROMIDE; IN-VITRO; INTERCALATIVE MODE; INTRINSIC BINDING; NI COMPLEXES; NI(II) COMPLEX; SINGLE CRYSTAL X-RAY DIFFRACTION; SPECTROMETRIC TITRATION; THIOSEMICARBAZONES;

CELL CULTURE; CELL MEMBRANES; CRYSTAL STRUCTURE; DNA; GENES; LIGANDS; NICKEL; NUCLEIC ACIDS; SINGLE CRYSTALS; SYNTHESIS (CHEMICAL); VISCOSITY MEASUREMENT;

COMPLEXATION;

EID: 70350087360     PISSN: 0022328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jorganchem.2009.08.024     Document Type: Article

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