Transcriptional activation of PPARα by phenobarbital in the absence of CAR and PXR

Molecular Pharmaceutics

Volumn 6, Issue 5, 2009, Pages 1573-1581

  Tamasi, Viola ^a,c   Juvan, Peter ^b   Beer, Markus ^a   Rozman, Damjana ^b   Meyer, Urs A ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

^c SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

AMPK; CAR PXR ; CAR ; HNF 4 ; Microarrays; Phenobarbital; PPAR ; PXR

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ADENYLATE KINASE; COMPLEMENTARY DNA; CONSTITUTIVE ANDROSTANE RECEPTOR; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PHENOBARBITAL; PREGNANE X RECEPTOR; RNA; TRANSCRIPTOME; CELL RECEPTOR; CYP4A10 PROTEIN, MOUSE; CYP4A14 PROTEIN, MOUSE; CYTOCHROME P450; DNA; HEPATOCYTE NUCLEAR FACTOR 4; HNF4A PROTEIN, MOUSE; MESSENGER RNA; STEROID RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; BIOSYNTHESIS; CONFERENCE PAPER; CONTROLLED STUDY; DNA MICROARRAY; DRUG EFFECT; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; KNOCKOUT MOUSE; LIVER; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE DRUG DOSE; TRANSCRIPTION INITIATION; TRANSGENIC MOUSE; ANIMAL; ARTICLE; BINDING SITE; BIOLOGICAL MODEL; C57BL MOUSE; CELL CULTURE; GENETICS; LIVER CELL; METABOLISM; MOUSE MUTANT; SIGNAL TRANSDUCTION;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; DNA; HEPATOCYTE NUCLEAR FACTOR 4; HEPATOCYTES; LIVER; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PHENOBARBITAL; PPAR ALPHA; RECEPTOR CROSS-TALK; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 70350077961     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp9001552     Document Type: Conference Paper

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