Pre-transplant obesity in heart transplantation: Are there predictors of worse outcomes?

Scandinavian Cardiovascular Journal

Volumn 43, Issue 5, 2009, Pages 304-310

  Macha, Mahender ^a,c   Molina, Ezequiel J ^b   Franco, Michael ^b   Luyun, Lisa ^b   Gaughan, John P ^b   Mcclurken, James B ^b   Furukawa, Satoshi ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Biostatistics Consulting Center Temple University School of Medicine ^*  (United States)

Author keywords

Heart transplantation; Obesity; Outcomes; Risk factors

Indexed keywords

INOTROPIC AGENT;

ADULT; ARTICLE; BODY MASS; CAUSE OF DEATH; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; FOLLOW UP; GRAFT REJECTION; HEART FAILURE; HEART TRANSPLANTATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORBID OBESITY; MORBIDITY; PERIPHERAL VASCULAR DISEASE; POSTOPERATIVE COMPLICATION; PREOPERATIVE EVALUATION; PREOPERATIVE PERIOD; PRIORITY JOURNAL; SURGICAL INFECTION; SURGICAL MORTALITY; SURGICAL RISK; SURVIVAL RATE; TREATMENT CONTRAINDICATION; TREATMENT OUTCOME; AGED; COMPLICATION; GRAFT SURVIVAL; HOSPITAL ADMISSION; KAPLAN MEIER METHOD; MIDDLE AGED; MORTALITY; PROPORTIONAL HAZARDS MODEL; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SURGICAL WOUND INFECTION; TIME; UNITED STATES;

ADULT; AGED; BODY MASS INDEX; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; HEART FAILURE; HEART TRANSPLANTATION; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; OBESITY, MORBID; PHILADELPHIA; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SURGICAL WOUND INFECTION; TIME FACTORS; TREATMENT OUTCOME; WAITING LISTS;

EID: 70350066657     PISSN: 14017431     EISSN: 16512006     Source Type: Journal    
DOI: 10.1080/14017430902810911     Document Type: Article

References (11)

1. Department of Health and Human Services, Centers for Disease Control and Prevention. State specific prevalence of obesity among adults-United States, 2005. MMWR. 2006;55:985.
2. Dohener W, Anker SD, Coats AJ. Defects in insulin action in chronic heart failure. Diabetes Obes Metab. 2000;2:203.
3. Thom T, Haase N, Rosamond W, Howard VJ, Rumsfeld J, Manolio T, et al. Heart disease and stroke statistics-2006 Update. Circulation. 2006;113:85.
4. Taylor DO, Edwards LB, Boucek MM, Trulock EP, Deng MC, Keck BM, et al. Registry of the ISHLT:22nd Official Adult Heart Transplant Report-2005. J Heart Lung Transplant. 2005;24:945.
5. Kocher AA, Ankersmit J, Khazen C, Ofner P, Zuckermann A, Grimm M, et al. Effect of obesity on outcome after cardiac transplantation. Transplant Proc. 1999;31:3187.
6. Grady KL, Constanzo MR, Fisher S, Koch D. Preoperative obesity is associated with decreased survival after heart transplantation. J Heart Lung Transplant. 1996;15:863.
7. Grady KL, White-Williams C, Naftel D, Costanzo MR, Pitts D, Rayburn B, et al. Are preoperative obesity and cachexia risk factors for post heart transplant morbidity and mortality: A multi-institutional study of preoperative weight-height indices. J Heart Lung Transplant. 1999;18:750.
8. Lietz K, John R, Burke EA, Ankersmit JH, McCue JD, Naka Y, et al. Pretransplant cachexia and morbid obesity are predictors of increased mortality after heart transplantation. Transplantation. 2001;72:277.
9. Cimato TR, Jessup M. Recipient selection in cardiac transplantation: Contraindications and risk factors for mortality. J Heart Lung Transplant. 2002;21:1161.
10. Wigfield CH, Lindsey JD, Muñoz A, Chopra PS, Edwards NM, Love RB. Is extreme obesity a risk factor for cardiac surgery? An analysis of patients with a BMI-40. Euro J Cardiothor Surg. 2006;29:434.
11. Winters GL, Kendall TJ, Radio SJ, Wilson JE, Costanzo-Nordin MR, Switzer BL, et al. Post transplant obesity and hyperlipidemia: Major predictors of severity of coronary arteriopathy in failed human heart allografts. J Heart Lung Transplant. 1990;9:364.