Plasma concentration of prolactin, testosterone might be associated with brain response to visual erotic stimuli in healthy heterosexual males

Psychiatry Investigation

Volumn 6, Issue 3, 2009, Pages 194-203

  Seo, Younghee ^a   Jeong, Bumseok ^a   Kim, Ji Woong ^b   Choi, Jeewook ^c  

^a Eulji University   (South Korea)

^b Kongyang University   (South Korea)

^c Daejeon St Mary's Hospital   (South Korea)

Author keywords

Dopamine; Magnetic resonance imaging; Prolactin; Sexual behavior; Testosterone

Indexed keywords

PROLACTIN; SEX HORMONE; TESTOSTERONE;

ADULT; ARTICLE; BRAIN REGION; ELECTROENCEPHALOGRAM; EROTISM; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HETEROSEXUAL MALE; HORMONE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; SEXUAL BEHAVIOR; VISUAL STIMULATION;

EID: 70350054438     PISSN: 17383684     EISSN: None     Source Type: Journal    
DOI: 10.4306/pi.2009.6.3.194     Document Type: Article

References (51)

1. Brotto LA, Woo JS, Ryder AG. Acculturation and sexual function in Canadian East Asian men. J Sex Med 2007;4:72-82.
2. Dunn KM, Croft PR, Hackett GI. Association of sexual problems with social, psychological, and physical problems in men and women: a cross sectional population survey. J Epidemiol Community Health 1999;53:144-148.
3. Hsueh WA. Sexual dysfunction with aging and systemic hypertension. Am J Cardiol 1988;61:18H-23H.
4. Okazaki S. Influences of culture on Asian Americans' sexuality. J Sex Res 2002;39:34-41. (Pubitemid 34552917)
5. Carmichael MS, Humbert R, Dixen J, Palmisano G, Greenleaf W, Davidson JM. Plasma oxytocin increases in the human sexual response. J Clin Endocrinol Metab 1987;64:27-31.
6. Arletti R, Bazzani C, Castelli M, Bertolini A. Oxytocin improves male copulatory performance in rats. Horm Behav 1985;19:14-20. (Pubitemid 15139047)
7. Krüger TH, Haake P, Chereath D, Knapp W, Janssen OE, Exton MS, et al. Specificity of the neuroendocrine response to orgasm during sexual arousal in men. J Endocrinol 2003;177:57-64. (Pubitemid 36592587)
8. Krüger TH, Haake P, Haverkamp J, Krämer M, Exton MS, Saller B, et al. Effects of acute prolactin manipulation on sexual drive and function in males. J Endocrinol 2003;179:357-365. (Pubitemid 38072087)
9. Buvat J, Lemaire A, Buvat-Herbaut M, Fourlinnie JC, Racadot A, Fossati P. Hyperprolactinemia and sexual function in men. Horm Res 1985;22:196-203.
10. Corona G, Mannucci E, Fisher AD, Lotti F, Ricca V, Balercia G, et al. Effect of hyperprolactinemia in male patients consulting for sexual dysfunction. J Sex Med 2007;4:1485-1493. (Pubitemid 47337698)
11. Ufearo CS, Orisakwe OE. Restoration of normal sperm characteristics in hypoprolactinemic infertile men treated with metoclopramide and exogenous human prolactin. Clin Pharmacol Ther 1995;58:354-359.
12. Corona G, Mannucci E, Jannini EA, Lotti F, Ricca V, Monami M, et al. Hypoprolactinemia: a new clinical syndrome in patients with sexual dysfunction. J Sex Med 2009;6:1457-1466.
13. Kwan M, Greenleaf WJ, Mann J, Crapo L, Davidson JM. The nature of androgen action on male sexuality: a combined laboratory-self-report study on hypogonadal men. J Clin Endocrinol Metab 1983;57:557-562.
14. Rowland DL, Heiman JR, Gladue BA, Hatch JP, Doering CH, Weiler SJ. Endocrine, psychological and genital response to sexual arousal in men. Psychoneuroendocrinology 1987;12:149-158.
15. Wallen K. Sex and context: hormones and primate sexual motivation. Horm Behav 2001:40:339-357. (Pubitemid 32846365)
16. Traish AM, Goldstein I, Kim NN. Testosterone and erectile function: from basic research to a new clinical paradigm for managing men with androgen insufficiency and erectile dysfunction. Eur Urol 2007;52:54-70. (Pubitemid 46803026)
17. Piekarski DJ, Routman DM, Schoomer EE, Driscoll JR, Park JH, Butler MP, et al. Infrequent low dose testosterone treatment maintains male sexual behavior in Syrian hamsters. Horm Behav 2009;55:182-189.
18. Rupp HA, Wallen K. Relationship between testosterone and interest in sexual stimuli: the effect of experience. Horm Behavior 2007;52:581-589. (Pubitemid 350087055)
19. Bocher M, Chisin R, Parag Y, Freedman N, Meir Weil Y, Lester H, et al. Cerebral activation associated with sexual arousal in response to a pornographic clip: a 15O-H2O PET study in heterosexual men. Neuroimage 2001;14(1 pt 1):105-117. (Pubitemid 32552747)
20. Redouté J, Stoléru S, Grégoire MC, Costes N, Cinotti L, Lavenne F, et al. Brain processing of visual sexual stimuli in human males. Hum Brain Mapp 2000;11:162-177.
21. Stoléru S, Grégoire MC, Gérard D, Decety J, Lafarge E, Cinotti L, et al. Neuroanatomical correlates of visually evoked sexual arousal in human males. Arch Sex Behav 1999;28:1-21.
22. Arnow BA, Desmond JE, Banner LL, Glover GH, Solomon A, Polan ML, et al. Brain activation and sexual arousal in healthy, heterosexual males. Brain 2002;125(pt 5):1014-1023. (Pubitemid 34464614)
23. Ferretti A, Caulo M, Del Gratta C, Di Matteo R, Merla A, Montorsi F, et al. Dynamics of male sexual arousal: distinct components of brain activation revealed by fMRI. Neuroimage 2005;26:1086-1096. (Pubitemid 40806487)
24. Kim SW, Sohn DW, Cho YH, Yang WS, Lee KU, Juh R, et al. Brain activation by visual erotic stimuli in healthy middle aged males. Int J Impot Res 2006;18:452-457. (Pubitemid 44330295)
25. Mouras H, Stoléru S, Bittoun J, Glutron D, Pélé grini-Issac M, Paradis AL, et al. Brain processing of visual sexual stimuli in healthy men: a functional magnetic resonance imaging study. Neuroimage 2003;20:855-869. (Pubitemid 37268109)
26. Karama S, Lecours AR, Leroux JM, Bourgouin P, Beaudoin G, Joubert S, et al. Areas of brain activation in males and females during viewing of erotic film excerpts. Hum Brain Mapp 2002;16:1-13.
27. Bühler M, Vollstädt-Klein S, Klemen J, Smolka MN. Does erotic Stimulus presentation design affect brain activation patterns? Event-related vs. blocked fMRI designs. Behav Brain Funct 2008;4:30.
28. Lang PJ, Bradley MM, Cuthbert BN. International affective picture system (IAPS): Affective ratings of pictures and instruction manual. Technical report A-8. Gaineville, FL: University of florida; 2008.
29. Brambilla DJ, Matsumoto AM, Araujo AB, McKinlay JB. The effect of diurnal variation on clinical measurement of serum testosterone and other sex hormone levels in men. J Clin Endocrinol Metab 2009;94:907-913.
30. Matchock RL, Dorn LD, Susman EJ. Diurnal and seasonal cortisol, testosterone, and DHEA rhythms in boys and girls during puberty. Chronobiology Int 2007;24:969-990.
31. Jenkinson M, Smith S. A global optimisation method for robust affine registration of brain images. Med Image Anal 2001;5:143-156. (Pubitemid 35282800)
32. Cruz-Casallas PE, Nasello AG, Hucke EE, Felicio LF. Dual modulation of male sexual behavior in rats by central prolactin: relationship with in vivo striatal dopaminergic activity. Psychoneuroendocrinology 1999;24:681-693.
33. Drago F, Lissandrello CO. The "low-dose" concept and the paradoxical effects of prolactin on grooming and sexual behavior. Eur J Pharmacol 2000;405:131-137.
34. Tanji J. The supplementary motor area in the cerebral cortex. Neurosci Res 1994;19:251-268. (Pubitemid 24146905)
35. Lee D, Quessy S. Activity in the supplementary motor area related to learning and performance during a sequential visuomotor task. J Neurophysiol 2003;89:1039-1056. (Pubitemid 36206150)
36. Matsuzaka Y, Tanji J. Changing directions of forthcoming arm movements: neuronal activity in the presupplementary and supplementary motor area of monkey cerebral cortex. J Neurophysiol 1996;76:2327-2342. (Pubitemid 26346409)
37. Shima K, Tanji J. Neuronal activity in the supplementary and presupplementary motor areas for temporal organization of multiple movements. J Neurophysiol 2000;84:2148-2160. (Pubitemid 30786980)
38. Oliveri M, Babiloni C, Filippi MM, Caltagirone C, Babiloni F, Cicinelli P, et al. Influence of the supplementary motor area on primary motor cortex excitability during movements triggered by neutral or emotionally unpleasant visual cues. Exp Brain Res 2003;149:214-221.
39. Moulier V, Mouras H, Pélégrini-Issac M, Glutron D, Rouxel R, Grandjean B, et al. Neuroanatomical correlates of penile erection evoked by photographic stimuli in human males. Neuroimage 2006;33:689-699.
40. Nogami H, Hoshino R, Ogasawara K, Miyamoto S, Hisano S. Region-specific expression and hormonal regulation of the first exon variants of rat prolactin receptor mRNA in rat brain and anterior pituitary gland. J Neuroendocrinol 2007;19:583-593. (Pubitemid 47065104)
41. Bakowska JC, Morrell JI. Atlas of the neurons that express mRNA for the long form of the prolactin receptor in the forebrain of the female rat. J Comp Neurol 1997;386:161-177.
42. Roky R, Paut-Pagano L, Goffin V, Kitahama K, Valatx JL, Kelly PA, et al. Distribution of prolactin receptors in the rat forebrain. Immunohistochemical study. Neuroendocrinology 1996;63:422-429.
43. Krüger TH, Haake P, Hartmann U, Schedlowski M, Exton MS. Orgasm-induced prolactin secretion: feedback control of sexual drive? Neurosci Biobehav Rev 2002;26:31-44.
44. Hull EM, Lorrain DS, Du J, Matuszewich L, Lumley LA, Putnam SK, et al. Hormone-neurotransmitter interactions in the control of sexual behavior. Behav Brain Res 1999;105:105-116. (Pubitemid 29447616)
45. Nokin J, Vekemans M, L'Hermite M, Robyn C. Circadian periodicity of serum prolactin concentration in man. Br Med J 1972;3:561-562.
46. Waldstreicher J, Duffy JF, Brown EN, Rogacz S, Allan JS, Czeisler CA. Gender differences in the temporal organization of proclactin (PRL) secretion: evidence for a sleep-independent circadian rhythm of circulating PRL levels- a clinical research center study. J Clin Endocrinol Metab 1996;81:1483-1487. (Pubitemid 26118580)
47. Grewen KM, Girdler SS, Amico J, Light KC. Effects of partner support on resting oxytocin, cortisol, norepinephrine, and blood pressure before and after warm partner contact. Psychosom Med 2005;67:531-538. (Pubitemid 41033580)
48. Young LJ, Wang Z. The neurobiology of pair bonding. Nat Neurosci 2004;7:1048-1054.
49. Bartels A, Zeki S. The neural correlates of maternal and romantic love. Neuroimage 2004;21:1155-1166. (Pubitemid 38314977)
50. Insel TR, Young LJ. The neurobiology of attachment. Nat Rev Neurosci 2001;2:129-136.
51. Walter M, Bermpohl F, Mouras H, Schiltz K, Tempelmann C, Rotte M, et al. Distinguishing specific sexual and general emotional effects in fMRI-subcortical and cortical arousal during erotic picture viewing. Neuroimage 2008;40:1482-1494.