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Volumn 45, Issue 6, 2009, Pages 423-430

Rilonacept in the treatment of chronic inflammatory disorders

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; INTERLEUKIN 1BETA; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RILONACEPT;

EID: 70350045050     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: 10.1358/dot.2009.45.6.1378935     Document Type: Review
Times cited : (46)

References (47)
  • 2
    • 62649139025 scopus 로고    scopus 로고
    • Immunological and inflammatory functions of the interleukin-1 family
    • Dinarello, C.A. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 2009, 27: 519-50.
    • (2009) Annu Rev Immunol , vol.27 , pp. 519-550
    • Dinarello, C.A.1
  • 3
    • 1642285783 scopus 로고    scopus 로고
    • NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
    • DOI 10.1016/S1074-7613(04)00046-9, PII S1074761304000469
    • Agostini, L., Martinon, F., Burns, K., McDermott, M.F., Hawkins, P.N., Tschopp, J. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 2004, 20(3): 319-325 (Pubitemid 38388233)
    • (2004) Immunity , vol.20 , Issue.3 , pp. 319-325
    • Agostini, L.1    Martinon, F.2    Burns, K.3    McDermott, M.F.4    Hawkins, P.N.5    Tschopp, J.6
  • 4
    • 33845497181 scopus 로고    scopus 로고
    • Inflammatory caspases and inflammasomes: Master switches of inflammation
    • DOI 10.1038/sj.cdd.4402038, PII 4402038
    • Martinon, F., Tschopp, J. Inflammatory caspases and inflammasomes: Master switches of inflammation. Cell Death Differ 2007, 14(1): 10-22. (Pubitemid 44911890)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.1 , pp. 10-22
    • Martinon, F.1    Tschopp, J.2
  • 5
    • 18644374105 scopus 로고    scopus 로고
    • Blocking IL-1 in systemic inflammation
    • Dinarello, C.A. Blocking IL-1 In systemic inflammation. J Exp Med 2005, 201(9): 1355-1359
    • (2005) J Exp Med , vol.201 , Issue.9 , pp. 1355-1359
    • Dinarello, C.A.1
  • 7
    • 0037792866 scopus 로고    scopus 로고
    • Interleukin-1-receptor antagonist in the Muckle-Wells syndrome
    • Hawkins, P.N., Lachmann, H.J., McDermott, M.F. Interleukin-1-receptor antagonist in the Muckle-Wells syndrome. N Engl J Med 2003, 348(25): 2583-2584
    • (2003) N Engl J Med , vol.348 , Issue.25 , pp. 2583-2584
    • Hawkins, P.N.1    Lachmann, H.J.2    McDermott, M.F.3
  • 9
    • 0001380014 scopus 로고
    • A case of cold urticaria with an unusual family history
    • Kile, R. L., Rusk, H.A. A case of cold urticaria with an unusual family history. JAMA 1940, 114(12): 1067-1068
    • (1940) JAMA , vol.114 , Issue.12 , pp. 1067-1068
    • Kile, R.L.1    Rusk, H.A.2
  • 10
    • 73649189052 scopus 로고
    • Urticaria, deafness, and amyloidosis: A new heredo-familial syndrome
    • Muckle, T.J., Wells, M. Urticaria, deafness, and amyloidosis: A new heredo-familial syndrome. Q J Med 1962, 31: 235-248
    • (1962) Q J Med , vol.31 , pp. 235-248
    • Muckle, T.J.1    Wells, M.2
  • 12
    • 34548476041 scopus 로고    scopus 로고
    • Hereditary immunologic disorders caused by pyrin and cryopyrin
    • Hoffman, H.M. Hereditary immunologic disorders caused by pyrin and cryopyrin. Curr Allergy Asthma Rep 2007, 7(5): 323-330
    • (2007) Curr Allergy Asthma Rep , vol.7 , Issue.5 , pp. 323-330
    • Hoffman, H.M.1
  • 14
    • 0035179970 scopus 로고    scopus 로고
    • Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
    • Hoffman, H.M., Mueller, J.L., Broide, D.H., Wanderer, A.A., Kolodner, R.D. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet 2001, 29(3): 301-305
    • (2001) Nat Genet , vol.29 , Issue.3 , pp. 301-305
    • Hoffman, H.M.1    Mueller, J.L.2    Broide, D.H.3    Wanderer, A.A.4    Kolodner, R.D.5
  • 16
    • 0036745064 scopus 로고    scopus 로고
    • Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis
    • Aganna, E., Martinon, F., Hawkins, P.N. et al. Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. Arthritis Rheum 2002, 46(9): 2445-2452
    • (2002) Arthritis Rheum , vol.46 , Issue.9 , pp. 2445-2452
    • Aganna, E.1    Martinon, F.2    Hawkins, P.N.3
  • 17
    • 4043104941 scopus 로고    scopus 로고
    • Response to anakinra in a de novo case of neonatal-onset multisystem inflammatory disease
    • DOI 10.1002/art.20357
    • Hawkins, P.N., Bybee, A., Aganna, E., McDermott, M.F. Response to anakinra in a de novo case of neonatal-onset multisystem inflammatory disease. Arthritis Rheum 2004, 50(8): 2708-2709 (Pubitemid 39062735)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.8 , pp. 2708-2709
    • Hawkins, P.N.1    Bybee, A.2    Aganna, E.3    McDermott, M.F.4
  • 18
    • 1042290321 scopus 로고    scopus 로고
    • Spectrum of Clinical Features in Muckle-Wells Syndrome and Response to Anakinra
    • DOI 10.1002/art.20033
    • Hawkins, P.N., Lachmann, H.J., Aganna, E., McDermott, M.F. Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum 2004, 50(2): 607-612 (Pubitemid 38198844)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.2 , pp. 607-612
    • Hawkins, P.N.1    Lachmann, H.J.2    Aganna, E.3    McDermott, M.F.4
  • 19
    • 8444225132 scopus 로고    scopus 로고
    • Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist
    • DOI 10.1016/S0140-6736(04)17401-1, PII S0140673604174011
    • Hoffman, H.M., Rosengren, S., Boyle, D.L. et al. Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist. Lancet 2004, 364(9447): 1779-1785 (Pubitemid 39488063)
    • (2004) Lancet , vol.364 , Issue.9447 , pp. 1779-1785
    • Hoffman, H.M.1    Rosengren, S.2    Boyle, D.L.3    Cho, J.Y.4    Nayar, J.5    Mueller, J.L.6    Anderson, J.P.7    Wanderer, A.A.8    Firestein, G.S.9
  • 22
    • 39449098500 scopus 로고    scopus 로고
    • New CIAS1 mutation and anakinra efficacy in overlapping of Muckle-Wells and familial cold autoinflammatory syndromes
    • Oxford
    • Maksimovic, L., Stirnemann, J., Caux, F. et al. New CIAS1 mutation and anakinra efficacy in overlapping of Muckle-Wells and familial cold autoinflammatory syndromes. Rheumatology (Oxford) 2008, 47(3): 309-310
    • (2008) Rheumatology , vol.47 , Issue.3 , pp. 309-310
    • Maksimovic, L.1    Stirnemann, J.2    Caux, F.3
  • 23
    • 33646492304 scopus 로고    scopus 로고
    • Recovery from deafness in a patient with Muckle-Wells syndrome treated with anakinra
    • Mirault, T., Launay, D., Cuisset, L. et al. Recovery from deafness in a patient with Muckle-Wells syndrome treated with anakinra. Arthritis Rheum 2006, 54(5): 1697-1700
    • (2006) Arthritis Rheum , vol.54 , Issue.5 , pp. 1697-1700
    • Mirault, T.1    Launay, D.2    Cuisset, L.3
  • 25
    • 40549122679 scopus 로고    scopus 로고
    • Use of anakinra (Kineret) in the treatment of familial cold autoinflammatory syndrome with a 16-month follow-up
    • Ross, J.B., Finlayson, L.A., Klotz, P.J. et al. Use of anakinra (Kineret) in the treatment of familial cold autoinflammatory syndrome with a 16-month follow-up. J Cutan Med Surg 2008, 12(1): 8-16.
    • (2008) J Cutan Med Surg , vol.12 , Issue.1 , pp. 8-16
    • Ross, J.B.1    Finlayson, L.A.2    Klotz, P.J.3
  • 26
    • 33645125321 scopus 로고    scopus 로고
    • Hearing improvement in a patient with variant Muckle-Wells syndrome in response to interleukin 1 receptor antagonism
    • Rynne, M., Maclean, C., Bybee, A., McDermott, M.F., Emery, P. Hearing improvement in a patient with variant Muckle-Wells syndrome in response to interleukin 1 receptor antagonism. Ann Rheum Dis 2006, 65(4): 533-534
    • (2006) Ann Rheum Dis , vol.65 , Issue.4 , pp. 533-534
    • Rynne, M.1    Maclean, C.2    Bybee, A.3    McDermott, M.F.4    Emery, P.5
  • 28
    • 58849156486 scopus 로고    scopus 로고
    • Canakinumab, a fully-human mAb against IL-1beta for the potential treatment of inflammatory disorders
    • Church, L.D., McDermott, M. Canakinumab, a fully-human mAb against IL-1beta for the potential treatment of inflammatory disorders. Curr Opin Mol Ther 2009, 11(1): 81-89
    • (2009) Curr Opin Mol Ther , vol.11 , Issue.1 , pp. 81-89
    • Church, L.D.1    McDermott, M.2
  • 29
    • 0037231664 scopus 로고    scopus 로고
    • Cytokine traps: Multi-component, high-affinity blockers of cytokine action
    • Economides, A.N., Carpenter, L.R., Rudge, J.S. et al. Cytokine traps: Multi-component, high-affinity blockers of cytokine action. Nat Med 2003, 9(1): 47-52.
    • (2003) Nat Med , vol.9 , Issue.1 , pp. 47-52
    • Economides, A.N.1    Carpenter, L.R.2    Rudge, J.S.3
  • 30
    • 0037231538 scopus 로고    scopus 로고
    • Setting the cytokine trap for autoimmunity
    • Dinarello, C.A. Setting the cytokine trap for autoimmunity. Nat Med 2003, 9(1): 20-22
    • (2003) Nat Med , vol.9 , Issue.1 , pp. 20-22
    • Dinarello, C.A.1
  • 31
    • 58049194057 scopus 로고    scopus 로고
    • Rilonacept in cryopyrin-associated periodic syndromes: The beginning of longer-acting interleukin-1 antagonism
    • Church, L.D., McDermott, M.F. Rilonacept in cryopyrin-associated periodic syndromes: The beginning of longer-acting interleukin-1 antagonism. Nat Clin Pract Rheumatol 2009, 5(1): 14-15
    • (2009) Nat Clin Pract Rheumatol , vol.5 , Issue.1 , pp. 14-15
    • Church, L.D.1    McDermott, M.F.2
  • 32
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • DOI 10.1038/nature04516, PII N04516
    • Martinon, F., Petriltl, V., Mayor, A., Tardivel, A., Tschopp, J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006, 440(7081): 237-241 (Pubitemid 43372104)
    • (2006) Nature , vol.440 , Issue.7081 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 33
    • 0022445268 scopus 로고
    • Cytotoxicity of human pI 7 Interleukin-1 for pancreatic islets of Langerhans
    • Bendtzen, K., Mandrup-Poulsen, T., Nerup, J., Nielsen, J.H., Dinarello, C.A., Svenson, M. Cytotoxicity of human pl 7 interleukin-1 for pancreatic Islets of Langerhans. Science 1986, 232(4757): 1545-1547 (Pubitemid 16061563)
    • (1986) Science , vol.232 , Issue.4757 , pp. 1545-1547
    • Bendtzen, K.1    Mandrup-Poulsen, T.2    Nerup, J.3
  • 34
    • 0029200358 scopus 로고
    • Circulating levels of interleukin 1beta and of interleukin 1 receptor antagonist in systemic juvenile chronic arthritis
    • De Benedetti, F., Pignatti, P., Massa, M., Sartirana, P., Ravelli, A., Martini, A. Circulating levels of interleukin 1 beta and of interleukin 1 receptor antagonist in systemic juvenile chronic arthritis. Clin Exp Rheumatol 1995, 13(6): 779-784 (Pubitemid 3011445)
    • (1995) Clinical and Experimental Rheumatology , vol.13 , Issue.6 , pp. 779-784
    • De Benedetti, F.1    Pignatti, P.2    Massa, M.3    Sartirana, P.4    Ravelli, A.5    Martini, A.6
  • 35
    • 0037091012 scopus 로고    scopus 로고
    • Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder
    • Wise, C.A., Gillum, J.D., Seidman, C.E. et al. Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder. Hum Mol Genet 2002, 11(8): 961-969
    • (2002) Hum Mol Genet , vol.11 , Issue.8 , pp. 961-969
    • Wise, C.A.1    Gillum, J.D.2    Seidman, C.E.3
  • 36
    • 44449110649 scopus 로고    scopus 로고
    • IL-1 Trap go-ahead
    • Ratner, M. IL-1 Trap go-ahead. Nat Biotechnol 2008, 26(5): 485.
    • (2008) Nat Biotechnol , vol.26 , Issue.5 , pp. 485
    • Ratner, M.1
  • 37
    • 67649286668 scopus 로고    scopus 로고
    • Rilonacept for the treatment of cryopyrin-associated periodic syndromes (CAPS)
    • Hoffman, H.M. Rilonacept for the treatment of cryopyrin-associated periodic syndromes (CAPS). Expert Opin Biol Ther 2009, 9(4): 519-531
    • (2009) Expert Opin Biol Ther , vol.9 , Issue.4 , pp. 519-531
    • Hoffman, H.M.1
  • 38
    • 49449094179 scopus 로고    scopus 로고
    • Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-ossociated periodic syndromes: Results from two sequential placebo-controlled studies
    • Hoffman, H.M., Throne, M.L., Amar, N.J. et al. Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-ossociated periodic syndromes: Results from two sequential placebo-controlled studies. Arthritis Rheum 2008, 58(8): 2443-2452
    • (2008) Arthritis Rheum , vol.58 , Issue.8 , pp. 2443-2452
    • Hoffman, H.M.1    Throne, M.L.2    Amar, N.J.3
  • 39
    • 70350065844 scopus 로고    scopus 로고
    • Long-term tafety of rilonacept (IL-1 Trap) in cryopyrin-associated periodic syndromes (CAPS): Results from a 1-year study
    • Fifth International Congr on Familial Mediterranean Fever and Systemic Autoinflammatory Diseases (April 4-8, Rome) 2008, Abst O13
    • Hoffman, H. M., Grimes, I. M., Weinstein, S.D. Long-term tafety of rilonacept (IL-1 Trap) in cryopyrin-associated periodic syndromes (CAPS): Results from a 1-year study. Clin Exp Rheumatol 2008, 26(2): 205-6. Fifth International Congr on Familial Mediterranean Fever and Systemic Autoinflammatory Diseases (April 4-8, Rome) 2008, Abst O13.
    • (2008) Clin Exp Rheumatol , vol.26 , Issue.2 , pp. 205-206
    • Hoffman, H.M.1    Grimes, I.M.2    Weinstein, S.D.3
  • 40
    • 49449094892 scopus 로고    scopus 로고
    • A pilot study to evaluate the safety and efficacy of the long-acting interleukin-1 inhibitor rilonacept (interleukin-1 Trap) in patients with familial cold autoinflammatory syndrome
    • Goldbach-Mansky, R., Shroff, S.D., Wilson, M. et al. A pilot study to evaluate the safety and efficacy of the long-acting interleukin-1 inhibitor rilonacept (interleukin-1 Trap) in patients with familial cold autoinflammatory syndrome. Arthritis Rheum 2008, 58(8): 2432-2442
    • (2008) Arthritis Rheum , vol.58 , Issue.8 , pp. 2432-2442
    • Goldbach-Mansky, R.1    Shroff, S.D.2    Wilson, M.3
  • 41
    • 70350075153 scopus 로고    scopus 로고
    • Rilonacept (IL-1 Trap) for treatment of colchicine resistant familial Mediterranean fever: A randomized, multicenter double-blinded, alternating treatment (N of 1) trial
    • Hashkes, P., Lovell, D., Giannini, E., Huang, B., Kastner, D. Rilonacept (IL-1 Trap) for treatment of colchicine resistant familial Mediterranean fever: A randomized, multicenter double-blinded, alternating treatment (N of 1) trial. Clin Exp Rheumatol 2008, 26(2): 193.
    • (2008) Clin Exp Rheumatol , vol.26 , Issue.2 , pp. 193
    • Hashkes, P.1    Lovell, D.2    Giannini, E.3    Huang, B.4    Kastner, D.5
  • 42
    • 48249151611 scopus 로고    scopus 로고
    • Placebo-controlled pilot study of rilonacept (IL-1 Trap), a long acting IL-1 inhibitor, in refractory chronic active gouty arthritis
    • [71st Annu Meet Am Coll Rheumatol (Nov 6-11, Boston) 2007] Abst L2
    • Terkeltaub, R., Schumacher, H.R., Sundy, J. et al. Placebo-controlled pilot study of rilonacept (IL-1 Trap), a long acting IL-1 inhibitor, in refractory chronic active gouty arthritis. Arthritis Rheum [71st Annu Meet Am Coll Rheumatol (Nov 6-11, Boston) 2007] 2007, 56(12): 4231-4232, Abst L2.
    • (2007) Arthritis Rheum , vol.56 , Issue.12 , pp. 4231-4232
    • Terkeltaub, R.1    Schumacher, H.R.2    Sundy, J.3
  • 43
    • 67449103755 scopus 로고    scopus 로고
    • Placebo-controlled pilot study of rilonacept (IL-1 Trap), a long acting IL-1 inhibitor, in refractory chronic active gouty arthritis
    • Radin, A., Terkeltaub, R., Schumacher, H. et al. Placebo-controlled pilot study of rilonacept (IL-1 Trap), a long acting IL-1 inhibitor, in refractory chronic active gouty arthritis. Clinical and Experimental Rheumatology 2008, 26(2): G5.
    • (2008) Clinical and Experimental Rheumatology , vol.26 , Issue.2
    • Radin, A.1    Terkeltaub, R.2    Schumacher, H.3
  • 44
    • 84878735739 scopus 로고    scopus 로고
    • Preliminary evidence for bioactivity of IL-1 Trap (rilonacept), a long acting IL-1 inhibitor, in systemic juvenile idiopathic arthritis
    • Abst LB0005
    • Lovell, D., Giannini, E., Kimura, Y. et al. Preliminary evidence for bioactivity of IL-1 Trap (rilonacept), a long acting IL-1 inhibitor, in systemic juvenile idiopathic arthritis. Annu Eur Congr Rheumatol (EULAR) (June 21-24, Amsterdam) 2006, Abst LB0005.
    • Annu Eur Congr Rheumatol (EULAR) (June 21-24, Amsterdam) 2006
    • Lovell, D.1    Giannini, E.2    Kimura, Y.3
  • 45
    • 34447635445 scopus 로고    scopus 로고
    • Preliminary evidence for bioactivity of IL-1 Trap (rilonacept), a long acting IL-1 inhibitor, in systemic juvenile idiopathic arthritis (SJIA)
    • [70th Annu Sci Meet Am Coll Rheumatol (Nov 10-15, Washington, D.C.) 2006] Abst 718
    • Lovell, D.J., Giannini, E.H., Kimura, Y. et al. Preliminary evidence for bioactivity of IL-1 Trap (rilonacept), a long acting IL-1 inhibitor, In systemic juvenile idiopathic arthritis (SJIA). Arthritis Rheum [70th Annu Sci Meet Am Coll Rheumatol (Nov 10-15, Washington, D.C.) 2006] 2006, 54(9, Suppl.): Abst 718.
    • (2006) Arthritis Rheum , vol.54 , Issue.9 SUPPL.
    • Lovell, D.J.1    Giannini, E.H.2    Kimura, Y.3
  • 46
    • 70350048308 scopus 로고    scopus 로고
    • Rilonacept [IL-1 Trap, Arcalyst; Regeneron Pharmaceuticals] has reduced the Incidence of gout flares in a phase II study
    • Rilonacept [IL-1 Trap, Arcalyst; Regeneron Pharmaceuticals] has reduced the Incidence of gout flares in a phase II study. Inpharma 2008, 1(1655); 9-9(1).
    • (2008) Inpharma , vol.1 , Issue.1655 , pp. 9-91
  • 47
    • 84878702591 scopus 로고    scopus 로고
    • http://clinicaltrials.gov/ct2/show/NCT00582907.


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