Identify drug-induced T wave morphology changes by a cell-to-electrocardiogram model and validation with clinical trial data

Journal of Electrocardiology

Volumn 42, Issue 6, 2009, Pages 534-542

  Xue, Joel ^a   Gao, Weihua ^b   Chen, Yao ^b   Han, Xiaodong ^b  

^a GE HEALTHCARE   (United States)

^b GE GLOBAL RESEARCH   (China)

Author keywords

Cell model; QT prolongation; T wave morphology; Transmural dispersion

Indexed keywords

DELAYED RECTIFIER POTASSIUM CHANNEL; ION CHANNEL;

ARTICLE; ELECTROCARDIOGRAM; ENDOCARDIUM; EPICARDIUM; HEART ARRHYTHMIA; HEART MUSCLE; HEART REPOLARIZATION; POTASSIUM CURRENT; PRIORITY JOURNAL; QT INTERVAL; SODIUM CURRENT; T WAVE; TORSADE DES POINTES;

ACTION POTENTIALS; CLINICAL TRIALS AS TOPIC; COMPUTER SIMULATION; DIAGNOSIS, COMPUTER-ASSISTED; ELECTROCARDIOGRAPHY; HEART CONDUCTION SYSTEM; HUMANS; MODELS, CARDIOVASCULAR; MYOCYTES, CARDIAC; SOTALOL;

EID: 70350043721     PISSN: 00220736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jelectrocard.2009.07.010     Document Type: Article

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