Nephrotic Syndrome in Diabetic Kidney Disease: An Evaluation and Update of the Definition

American Journal of Kidney Diseases

Volumn 54, Issue 5, 2009, Pages 840-849

  Stoycheff, Nicholas ^a   Stevens, Lesley A ^a   Schmid, Christopher H ^a   Tighiouart, Hocine ^a   Lewis, Julia ^b   Atkins, Robert C ^c   Levey, Andrew S ^a  

^a TUFTS MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c MONASH MEDICAL CENTRE   (Australia)

Author keywords

albumin creatinine ratio; albuminuria; chronic kidney disease progression; CKD; diabetic kidney disease; edema; hypercholesterolemia; hypoalbuminemia; Nephrotic syndrome; protein creatinine ratio; proteinuria; urine albumin; urine protein

Indexed keywords

AMLODIPINE; CHOLESTEROL; CREATININE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IRBESARTAN; LOOP DIURETIC AGENT; PLACEBO; PROTEIN; SERUM ALBUMIN;

ADULT; ALBUMIN BLOOD LEVEL; ALBUMINURIA; AREA UNDER THE CURVE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHRONIC KIDNEY DISEASE; CLINICAL EVALUATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETIC NEPHROPATHY; DIAGNOSTIC TEST; DISEASE COURSE; FEMALE; FOLLOW UP; HUMAN; HYPERTENSION; KIDNEY DISEASE; KIDNEY TRANSPLANTATION; LINEAR REGRESSION ANALYSIS; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; MULTICENTER STUDY; NEPHROTIC SYNDROME; NON INSULIN DEPENDENT DIABETES MELLITUS; OUTCOME ASSESSMENT; PERIPHERAL EDEMA; PROTEIN BLOOD LEVEL; PROTEINURIA; RANDOMIZED CONTROLLED TRIAL; URINALYSIS; URINARY EXCRETION;

ALBUMINURIA; CREATININE; DIABETIC NEPHROPATHIES; DISEASE PROGRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; NEPHROTIC SYNDROME;

EID: 70350020406     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.ajkd.2009.04.016     Document Type: Article

References (40)

1. Brenner B.M., Levine S.A., Rector F.C., and MD Consult LLC. Brenner & Rector's The Kidney. (ed 7) (2004), Saunders, Philadelphia, PA
2. Orth S.R., and Ritz E. The nephrotic syndrome. N Engl J Med 338 (1998) 1202-1211
3. Rivera F., Lopez-Gomez J.M., and Perez-Garcia R. Clinicopathologic correlations of renal pathology in Spain. Kidney Int 66 (2004) 898-904
4. Hunt L.P., Short C.D., and Mallick N.P. Prognostic indicators in patients presenting with the nephrotic syndrome. Kidney Int 34 (1988) 382-388
5. Ordonez J.D., Hiatt R.A., Killebrew E.J., and Fireman B.H. The increased risk of coronary heart disease associated with nephrotic syndrome. Kidney Int 44 (1993) 638-642
6. The primary nephrotic syndrome in children. Identification of patients with minimal change nephrotic syndrome from initial response to prednisone. A report of the International Study of Kidney Disease in Children. J Pediatr 98 (1981) 561-564
7. Fox T.F., and Douglas-Wilson I. The nephrotic syndrome. Lancet 2 (1958) 1000-1002
8. Jay V. Richard Bright-Physician extraordinaire. Arch Pathol Lab Med 124 (2000) 1262-1263
9. Peitzman S.J. From dropsy to Bright's disease to end-stage renal disease. Milbank Q 67 suppl 1 (1989) S16-S32
10. Strauss M.B., and Welt L.G. Diseases of the Kidney. (ed 2) (1963), Little Brown, Boston, MA
11. Ginsberg J.M., Chang B.S., Matarese R.A., and Garella S. Use of single voided urine samples to estimate quantitative proteinuria. N Engl J Med 309 (1983) 1543-1546
12. Vassalotti J.A., Stevens L.A., and Levey A.S. Testing for chronic kidney disease: A position statement from the National Kidney Foundation. Am J Kidney Dis 50 (2007) 169-180
13. National Kidney Foundation. K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, classification, and stratification. Am J Kidney Dis 39 suppl 1 (2002) S93-S102
14. National Kidney Foundation. KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Diabetes and Chronic Kidney Disease. Am J Kidney Dis 49 suppl 2 (2007) S12-S154
15. Miller W.G., Bruns D.E., Hortin G.L., et al. Current issues in measurement and reporting of urinary albumin. Clin Chem 55 (2009) 24-38
16. Lewis E.J., Hunsicker L.G., Clarke W.R., et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 345 (2001) 851-860
17. Heagerty P.J., and Zheng Y. Survival model predictive accuracy and ROC curves. Biometrics 61 (2005) 92-105
18. Atkins R.C., Briganti E.M., Lewis J.B., et al. Proteinuria reduction and progression to renal failure in patients with type 2 diabetes mellitus and overt nephropathy. Am J Kidney Dis 45 (2005) 281-287
19. Eknoyan G. A history of edema and its management. Kidney Int Suppl 59 (1997) S118-S126
20. Heidland A., Gerabek W., and Sebekova K. Franz Volhard and Theodor Fahr: Achievements and controversies in their research in renal disease and hypertension. J Hum Hypertens 15 (2001) 5-16
21. Epstein A.A. A contribution to the study of the chemistry of blood serum. J Exp Med 16 (1912) 719-731
22. Epstein A.A. Further studies on the chemistry of blood serum. J Exp Med 17 (1913) 444-452
23. Epstein A.A. Studies on the chemistry of serous effusions. J Exp Med 20 (1914) 334-345
24. Epstein A.A. Concerning the causation of edema in chronic parenchymatous nephritis; Method for its alleviation. Am J Med Sci 154 (1917) 638-647
25. Becker G.J. Which albumin should we measure?. Kidney Int Suppl 92 (2004) S16-S17
26. Nelson R.G., Bennett P.H., Beck G.J., et al. Development and progression of renal disease in Pima Indians with non-insulin-dependent diabetes mellitus. Diabetic Renal Disease Study Group. N Engl J Med 335 (1996) 1636-1642
27. Myers B.D., Nelson R.G., Tan M., et al. Progression of overt nephropathy in non-insulin-dependent diabetes. Kidney Int 47 (1995) 1781-1789
28. Lemley K.V., Blouch K., Abdullah I., et al. Glomerular permselectivity at the onset of nephropathy in type 2 diabetes mellitus. J Am Soc Nephrol 11 (2000) 2095-2105
29. Appel G.B., Blum C.B., Chien S., Kunis C.L., and Appel A.S. The hyperlipidemia of the nephrotic syndrome. Relation to plasma albumin concentration, oncotic pressure, and viscosity. N Engl J Med 312 (1985) 1544-1548
30. Fauchald P., Norseth J., and Jervell J. Transcapillary colloid osmotic gradient, plasma volume and interstitial fluid volume in long-term type 1 (insulin-dependent) diabetes. Diabetologia 28 (1985) 269-273
31. Hommel E., Mathiesen E.R., Aukland K., and Parving H.H. Pathophysiological aspects of edema formation in diabetic nephropathy. Kidney Int 38 (1990) 1187-1192
32. O'Brien T., Nguyen T.T., and Zimmerman B.R. Hyperlipidemia and diabetes mellitus. Mayo Clin Proc 73 (1998) 969-976
33. Kissebah A.H., Alfarsi S., Evans D.J., and Adams P.W. Plasma low density lipoprotein transport kinetics in noninsulin-dependent diabetes mellitus. J Clin Invest 71 (1983) 655-667
34. Sampietro T., Bertuglia S., Colantuoni A., Bionda A., Lenzi S., and Donato L. Increased permeability of hamster microcirculation to glycosylated albumin. Lancet 2 (1987) 994-996
35. Eknoyan G., Hostetter T., Bakris G.L., et al. Proteinuria and other markers of chronic kidney disease: A position statement of the National Kidney Foundation (NKF) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Am J Kidney Dis 42 (2003) 617-622
36. Levey A.S., Coresh J., Balk E., et al. National Kidney Foundation practice guidelines for chronic kidney disease: Evaluation, classification, and stratification. Ann Intern Med 139 (2003) 137-147
37. Sarnak M.J., Levey A.S., Schoolwerth A.C., et al. Kidney disease as a risk factor for development of cardiovascular disease: A statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation 108 (2003) 2154-2169
38. Chonchol M, Lippi G, Montagnana M, Muggeo M, Targher G: Association of inflammation with anaemia in patients with chronic kidney disease not requiring chronic dialysis. Nephrol Dial Transplant 23:2879-2883
39. Bakker A.J. Detection of microalbuminuria. Receiver operating characteristic curve analysis favors albumin-creatinine ratio over albumin concentration. Diabetes Care 22 (1999) 307-313
40. Chitalia V.C., Kothari J., Wells E.J., et al. Cost-benefit analysis and prediction of 24-hour proteinuria from the spot urine protein-creatinine ratio. Clin Nephrol 55 (2001) 436-447