메뉴 건너뛰기




Volumn 79, Issue 2, 2009, Pages 232-237

Use of resazurin to detect mefloquine as an efflux-pump inhibitor in Pseudomonas aeruginosa and Escherichia coli

Author keywords

Alamar Blue; Efflux; Escherichia coli; Mefloquine; Microtiter plate; Pseudomonas aeruginosa; Resazurin; Resorufin

Indexed keywords

CHEMICAL COMPOUND; MEFLOQUINE; RESAZURIN; RESORUFIN;

EID: 70350004050     PISSN: 01677012     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mimet.2009.09.021     Document Type: Article
Times cited : (29)

References (32)
  • 1
    • 0027160409 scopus 로고
    • Mutants of the Bacillus subtilis multidrug transporter Bmr with altered sensitivity to the antihypertensive alkaloid reserpine
    • Ahmed M., Borsch C.M., Neyfakh A.A., and Schuldiner S. Mutants of the Bacillus subtilis multidrug transporter Bmr with altered sensitivity to the antihypertensive alkaloid reserpine. J. Biol. Chem. 268 (1993) 11086-11089
    • (1993) J. Biol. Chem. , vol.268 , pp. 11086-11089
    • Ahmed, M.1    Borsch, C.M.2    Neyfakh, A.A.3    Schuldiner, S.4
  • 2
    • 12944316448 scopus 로고    scopus 로고
    • Selected arylpiperazines are capable of reversing multidrug resistance in Escherichia coli overexpressing RND efflux pumps
    • Bohnert J.A., and Kern W.V. Selected arylpiperazines are capable of reversing multidrug resistance in Escherichia coli overexpressing RND efflux pumps. Antimicrob. Agents Chemother. 49 (2005) 849-852
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 849-852
    • Bohnert, J.A.1    Kern, W.V.2
  • 3
    • 0034612342 scopus 로고    scopus 로고
    • One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
    • Datsenko K.A., and Wanner B.L. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 6640-6645
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 6640-6645
    • Datsenko, K.A.1    Wanner, B.L.2
  • 4
    • 0030994516 scopus 로고    scopus 로고
    • Molecular bases of three characteristic phenotypes of pneumococcus: optochin-sensitivity, coumarin-sensitivity, and quinolone-resistance
    • De la Campa A.G., Garcia E., Fenoll A., and Munoz R. Molecular bases of three characteristic phenotypes of pneumococcus: optochin-sensitivity, coumarin-sensitivity, and quinolone-resistance. Microb. Drug Resist. 3 (1997) 177-193
    • (1997) Microb. Drug Resist. , vol.3 , pp. 177-193
    • De la Campa, A.G.1    Garcia, E.2    Fenoll, A.3    Munoz, R.4
  • 5
    • 70350012610 scopus 로고    scopus 로고
    • Active drug efflux in bacteria
    • Bonomo R.A., and Tolmasky M. (Eds), Washington D.C, ASM Press
    • Dreier J. Active drug efflux in bacteria. In: Bonomo R.A., and Tolmasky M. (Eds). Enzyme-Mediated Resistance to Antibiotics (2007), Washington D.C, ASM Press 235-264
    • (2007) Enzyme-Mediated Resistance to Antibiotics , pp. 235-264
    • Dreier, J.1
  • 6
    • 0028310309 scopus 로고
    • Molecular basis of the optochin-sensitive phenotype of pneumococcus: characterization of the genes encoding the F0 complex of the Streptococcus pneumoniae and Streptococcus oralis H(+)-ATPases
    • Fenoll A., Munoz R., Garcia E., and de la Campa A.G. Molecular basis of the optochin-sensitive phenotype of pneumococcus: characterization of the genes encoding the F0 complex of the Streptococcus pneumoniae and Streptococcus oralis H(+)-ATPases. Mol. Microbiol. 12 (1994) 587-598
    • (1994) Mol. Microbiol. , vol.12 , pp. 587-598
    • Fenoll, A.1    Munoz, R.2    Garcia, E.3    de la Campa, A.G.4
  • 7
    • 0042835366 scopus 로고    scopus 로고
    • 4-Alkoxy and 4-thioalkoxyquinoline derivatives as chemosensitizers for the chloramphenicol-resistant clinical Enterobacter aerogenes 27 strain
    • Gallo S., Chevalier J., Mahamoud A., Eyraud A., Pages J.M., and Barbe J. 4-Alkoxy and 4-thioalkoxyquinoline derivatives as chemosensitizers for the chloramphenicol-resistant clinical Enterobacter aerogenes 27 strain. Int. J. Antimicrob. Agents 22 (2003) 270-273
    • (2003) Int. J. Antimicrob. Agents , vol.22 , pp. 270-273
    • Gallo, S.1    Chevalier, J.2    Mahamoud, A.3    Eyraud, A.4    Pages, J.M.5    Barbe, J.6
  • 8
    • 42949152261 scopus 로고    scopus 로고
    • The efflux pump inhibitor reserpine selects multidrug-resistant Streptococcus pneumoniae strains that overexpress the ABC transporters PatA and PatB
    • Garvey M.I., and Piddock L.J. The efflux pump inhibitor reserpine selects multidrug-resistant Streptococcus pneumoniae strains that overexpress the ABC transporters PatA and PatB. Antimicrob. Agents Chemother. 52 (2008) 1677-1685
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 1677-1685
    • Garvey, M.I.1    Piddock, L.J.2
  • 9
    • 44949197772 scopus 로고    scopus 로고
    • Inhibition of efflux of quinolines as new therapeutic strategy in malaria
    • Henry M., Alibert S., Rogier C., Barbe J., and Pradines B. Inhibition of efflux of quinolines as new therapeutic strategy in malaria. Curr. Top. Med. Chem. 8 (2008) 563-578
    • (2008) Curr. Top. Med. Chem. , vol.8 , pp. 563-578
    • Henry, M.1    Alibert, S.2    Rogier, C.3    Barbe, J.4    Pradines, B.5
  • 10
    • 0032575051 scopus 로고    scopus 로고
    • A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants
    • Hoang T.T., Karkhoff-Schweizer R.R., Kutchma A.J., and Schweizer H.P. A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants. Gene 212 (1998) 77-86
    • (1998) Gene , vol.212 , pp. 77-86
    • Hoang, T.T.1    Karkhoff-Schweizer, R.R.2    Kutchma, A.J.3    Schweizer, H.P.4
  • 12
    • 31544441414 scopus 로고    scopus 로고
    • Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Escherichia coli
    • Kern W.V., Steinke P., Schumacher A., Schuster S., von Baum H., and Bohnert J.A. Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Escherichia coli. J. Antimicrob. Chemother. 57 (2006) 339-343
    • (2006) J. Antimicrob. Chemother. , vol.57 , pp. 339-343
    • Kern, W.V.1    Steinke, P.2    Schumacher, A.3    Schuster, S.4    von Baum, H.5    Bohnert, J.A.6
  • 13
    • 33749511442 scopus 로고    scopus 로고
    • Method for regulated expression of single-copy efflux pump genes in a surrogate Pseudomonas aeruginosa strain: identification of the BpeEF-OprC chloramphenicol and trimethoprim efflux pump of Burkholderia pseudomallei 1026b
    • Kumar A., Chua K.L., and Schweizer H.P. Method for regulated expression of single-copy efflux pump genes in a surrogate Pseudomonas aeruginosa strain: identification of the BpeEF-OprC chloramphenicol and trimethoprim efflux pump of Burkholderia pseudomallei 1026b. Antimicrob. Agents Chemother. 50 (2006) 3460-3463
    • (2006) Antimicrob. Agents Chemother. , vol.50 , pp. 3460-3463
    • Kumar, A.1    Chua, K.L.2    Schweizer, H.P.3
  • 14
    • 0034026489 scopus 로고    scopus 로고
    • Antimicrobial activities of mefloquine and a series of related compounds
    • Kunin C.M., and Ellis W.Y. Antimicrobial activities of mefloquine and a series of related compounds. Antimicrob. Agents Chemother. 44 (2000) 848-852
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 848-852
    • Kunin, C.M.1    Ellis, W.Y.2
  • 15
    • 0035088330 scopus 로고    scopus 로고
    • In search of natural substrates and inhibitors of MDR pumps
    • Lewis K. In search of natural substrates and inhibitors of MDR pumps. J. Mol. Microbiol. Biotechnol. 3 (2001) 247-254
    • (2001) J. Mol. Microbiol. Biotechnol. , vol.3 , pp. 247-254
    • Lewis, K.1
  • 16
    • 33845711756 scopus 로고    scopus 로고
    • Prospects for plant-derived antibacterials
    • Lewis K., and Ausubel F.M. Prospects for plant-derived antibacterials. Nat. Biotechnol. 24 (2006) 1504-1507
    • (2006) Nat. Biotechnol. , vol.24 , pp. 1504-1507
    • Lewis, K.1    Ausubel, F.M.2
  • 17
    • 0036498656 scopus 로고    scopus 로고
    • Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare?
    • Livermore D.M. Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare?. Clin. Infect. Dis. 34 (2002) 634-640
    • (2002) Clin. Infect. Dis. , vol.34 , pp. 634-640
    • Livermore, D.M.1
  • 19
    • 0033856957 scopus 로고    scopus 로고
    • Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity
    • O'Brien J., Wilson I., Orton T., and Pognan F. Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. Eur. J. Biochem. 267 (2000) 5421-5426
    • (2000) Eur. J. Biochem. , vol.267 , pp. 5421-5426
    • O'Brien, J.1    Wilson, I.2    Orton, T.3    Pognan, F.4
  • 20
    • 9644274002 scopus 로고    scopus 로고
    • National surveillance of antimicrobial resistance in Pseudomonas aeruginosa isolates obtained from intensive care unit patients from 1993 to 2002
    • Obritsch M.D., Fish D.N., MacLaren R., and Jung R. National surveillance of antimicrobial resistance in Pseudomonas aeruginosa isolates obtained from intensive care unit patients from 1993 to 2002. Antimicrob. Agents Chemother. 48 (2002) 4606-4610
    • (2002) Antimicrob. Agents Chemother. , vol.48 , pp. 4606-4610
    • Obritsch, M.D.1    Fish, D.N.2    MacLaren, R.3    Jung, R.4
  • 21
    • 23144431968 scopus 로고    scopus 로고
    • Inhibitors of efflux pumps in Gram-negative bacteria
    • Pages J.M., Masi M., and Barbe J. Inhibitors of efflux pumps in Gram-negative bacteria. Trends Mol. Med. 11 (2005) 382-389
    • (2005) Trends Mol. Med. , vol.11 , pp. 382-389
    • Pages, J.M.1    Masi, M.2    Barbe, J.3
  • 22
    • 33645828405 scopus 로고    scopus 로고
    • Multidrug efflux inhibition in Acinetobacter baumannii: comparison between 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-beta-naphthylamide
    • Pannek S., Higgins P.G., Steinke P., Jonas D., Akova M., Bohnert J.A., Seifert H., and Kern W.V. Multidrug efflux inhibition in Acinetobacter baumannii: comparison between 1-(1-naphthylmethyl)-piperazine and phenyl-arginine-beta-naphthylamide. J. Antimicrob. Chemother. 57 (2006) 970-974
    • (2006) J. Antimicrob. Chemother. , vol.57 , pp. 970-974
    • Pannek, S.1    Higgins, P.G.2    Steinke, P.3    Jonas, D.4    Akova, M.5    Bohnert, J.A.6    Seifert, H.7    Kern, W.V.8
  • 23
    • 33646251815 scopus 로고    scopus 로고
    • Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria
    • Piddock L.J. Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria. Clin. Microbiol. Rev. 19 (2006) 382-402
    • (2006) Clin. Microbiol. Rev. , vol.19 , pp. 382-402
    • Piddock, L.J.1
  • 24
    • 33747154459 scopus 로고    scopus 로고
    • Multidrug-resistance efflux pumps - not just for resistance
    • Piddock L.J. Multidrug-resistance efflux pumps - not just for resistance. Nat. Rev. Microbiol. 4 (2006) 629-636
    • (2006) Nat. Rev. Microbiol. , vol.4 , pp. 629-636
    • Piddock, L.J.1
  • 25
    • 0033836084 scopus 로고    scopus 로고
    • Efflux-mediated resistance to fluoroquinolones in gram-negative bacteria
    • Poole K. Efflux-mediated resistance to fluoroquinolones in gram-negative bacteria. Antimicrob. Agents Chemother. 44 (2000) 2233-2241
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 2233-2241
    • Poole, K.1
  • 26
    • 1642422948 scopus 로고    scopus 로고
    • Efflux-mediated multiresistance in Gram-negative bacteria
    • Poole K. Efflux-mediated multiresistance in Gram-negative bacteria. Clin. Microbiol. Infect. 10 (2004) 12-26
    • (2004) Clin. Microbiol. Infect. , vol.10 , pp. 12-26
    • Poole, K.1
  • 27
    • 24044514016 scopus 로고    scopus 로고
    • Efflux-mediated antimicrobial resistance
    • Poole K. Efflux-mediated antimicrobial resistance. J. Antimicrob. Chemother. 56 (2005) 20-51
    • (2005) J. Antimicrob. Chemother. , vol.56 , pp. 20-51
    • Poole, K.1
  • 28
    • 0037397295 scopus 로고    scopus 로고
    • The efflux pump inhibitor Phe-Arg-beta-naphthylamide does not abolish the activity of the Stenotrophomonas maltophilia SmeDEF multidrug efflux pump
    • Sanchez P., Le U., and Martinez J.L. The efflux pump inhibitor Phe-Arg-beta-naphthylamide does not abolish the activity of the Stenotrophomonas maltophilia SmeDEF multidrug efflux pump. J. Antimicrob. Chemother. 51 (2003) 1042-1045
    • (2003) J. Antimicrob. Chemother. , vol.51 , pp. 1042-1045
    • Sanchez, P.1    Le, U.2    Martinez, J.L.3
  • 29
    • 31544464121 scopus 로고    scopus 로고
    • Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Enterobacteriaceae other than Escherichia coli
    • Schumacher A., Steinke P., Bohnert J.A., Akova M., Jonas D., and Kern W.V. Effect of 1-(1-naphthylmethyl)-piperazine, a novel putative efflux pump inhibitor, on antimicrobial drug susceptibility in clinical isolates of Enterobacteriaceae other than Escherichia coli. J. Antimicrob. Chemother. 57 (2006) 344-348
    • (2006) J. Antimicrob. Chemother. , vol.57 , pp. 344-348
    • Schumacher, A.1    Steinke, P.2    Bohnert, J.A.3    Akova, M.4    Jonas, D.5    Kern, W.V.6
  • 30
    • 0346694551 scopus 로고    scopus 로고
    • Efflux as a mechanism of resistance to antimicrobials in Pseudomonas aeruginosa and related bacteria: unanswered questions
    • Schweizer H.P. Efflux as a mechanism of resistance to antimicrobials in Pseudomonas aeruginosa and related bacteria: unanswered questions. Genet. Mol. Res. 2 (2003) 48-62
    • (2003) Genet. Mol. Res. , vol.2 , pp. 48-62
    • Schweizer, H.P.1
  • 31
    • 33749989605 scopus 로고    scopus 로고
    • Transporters involved in resistance to antimalarial drugs
    • Valderramos S.G., and Fidock D.A. Transporters involved in resistance to antimalarial drugs. Trends Pharmacol. Sci. 27 (2006) 594-601
    • (2006) Trends Pharmacol. Sci. , vol.27 , pp. 594-601
    • Valderramos, S.G.1    Fidock, D.A.2
  • 32
    • 34248400414 scopus 로고    scopus 로고
    • Inhibitors of bacterial efflux pumps as adjuvants in antibiotic treatments and diagnostic tools for detection of resistance by efflux. Recent patents
    • Van Bambeke F., Pages J.M., and Lee V.J. Inhibitors of bacterial efflux pumps as adjuvants in antibiotic treatments and diagnostic tools for detection of resistance by efflux. Recent patents. Anti-Infect. Drug Disc. 1 (2006) 157-175
    • (2006) Anti-Infect. Drug Disc. , vol.1 , pp. 157-175
    • Van Bambeke, F.1    Pages, J.M.2    Lee, V.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.