Mathematical modelling of interferon-γ signalling in pancreatic stellate cells reflects and predicts the dynamics of STAT1 pathway activity

Cellular Signalling

Volumn 22, Issue 1, 2010, Pages 97-105

  Rateitschak, Katja ^a   Karger, Anna ^a,b   Fitzner, Brit ^b   Lange, Falko ^a   Wolkenhauer, Olaf ^a   Jaster, Robert ^b  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b Medical Faculty   (Germany)

Author keywords

Interferon ; Mathematical modelling; Pancreatic stellate cells; STAT1

Indexed keywords

GAMMA INTERFERON; PROTEIN TYROSINE PHOSPHATASE; STAT1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL LINE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MATHEMATICAL MODEL; NONHUMAN; PANCREAS CELL; PREDICTION; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STELLATE CELL;

ANIMALS; CELLS, CULTURED; GENE EXPRESSION REGULATION; INTERFERON-GAMMA; MODELS, BIOLOGICAL; PANCREAS; RATS; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR;

EID: 70349992872     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2009.09.019     Document Type: Article

References (39)

1. Apte M.V., Park S., Phillips P.A., Santucci N., Goldstein D., Kumar R.K., Ramm G.A., Buchler M., Friess H., McCarroll J.A., Keogh G., Merrett N., Pirola R., and Wilson J.S. Pancreas 29 (2004) 179
2. Talukdar R., Saikia N., Singal D.K., and Tandon R. Pancreatology 6 (2006) 440
3. Jaster R., and Emmrich J. Best Pract. Res. Clin. Gastroenterol. 22 (2008) 17
4. Apte M.V., Haber P.S., Applegate T.L., Norton I.D., McCaughan G.W., Korsten M.A., Pirola R.C., and Wilson J.S. Gut 43 (1998) 128
5. Bachem M.G., Schneider E., Groß H., Weidenbach H., Schmid R.M., Menke A., Siech M., Beger H., Grünert A., and Adler G. Gastroenterology 115 (1998) 421
6. Haber P.S., Keogh G.W., Apte M.V., Moran C.S., Stewart N.L., Crawford D.H.G., Pirola R.C., McCaughan G.W., Ramm G.A., and Wilson J.S. Am. J. Pathol. 155 (1999) 1087
7. Luttenberger T., Schmid-Kotsas A., Menke A., Siech M., Beger H., Grünert A., and Adler G. Lab. Invest. 80 (2000) 47
8. Kruse M.L., Hildebrand P.B., Timke C., Fölsch U.R., and Schmidt W.E. Regul. Pept. 90 (2000) 47
9. Baumert J.T., Sparmann G., Emmrich J., Liebe S., and Jaster R. World J. Gastroenterol. 12 (2006) 896
10. Fitzner B., Brock P., Nechutova H., Glass A., Karopka T., Koczan D., Thiesen H.J., Sparmann G., Emmrich J., Liebe S., and Jaster R. Cell. Signal. 19 (2007) 782
11. Durbin J.E., Hackenmiller R., Simon M.C., and Levy D.E. Cell 84 (1996) 443
12. Meraz M.A., White J.M., Sheehan K.C.F., Bach E.A., Rodig S.J., Dighe A.S., Kaplan D.H., Riley J.K., Greenlund A.C., Campbell D., Carver-Moore K., DuBois R.N., Clark R., Aguet M., and Schreiber R.D. Cell 84 (1996) 431
13. Darnell Jr. J.E. Science 277 (1997) 1630
14. Stark G.R., Kerr I.M., Williams B.R., Silverman R.H., and Schreiber R.D. Annu. Rev. Biochem. 67 (1998) 227
15. Haspel R.L., and Darnell Jr. J.E. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 10,188
16. Massa P.T., and Wu C. J. Immunol. 157 (1996) 5139
17. You M., Yu D.H., and Feng G.S. Mol. Cell Biol. 19 (1999) 2416
18. Song M.M., and Shuai K. J. Biol. Chem. 273 (1998) 35,056
19. Krebs D.L., and Hilton D.J. Stem Cells 19 (2001) 378
20. Liu B., Liao J., Rao X., Kushner S.A., Chung C.D., Chang D.D., and Shuai K. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 10,626
21. Bach E.A., Szabo S.J., Dighe A.S., Ashkenazi A., Aguet M., Murphy K.M., and Schreiber S.D. Science 270 (1995) 1215
22. Li X., Leung S., Qureshi S., Darnell Jr. J.E., and Stark G.R. J. Biol. Chem. 271 (1996) 5790
23. Sparmann G., Hohenadl C., Tornoe J., Jaster R., Fitzner B., Koczan D., Thiesen H.J., Glass Ä., Winder D., Liebe S., and Emmrich J. Am. J. Physiol. Gastrointest. Liver Physiol. 287 (2004) G211
24. Hu X., Herrero C., Li W.P., Antoniv T.T., Falck-Pedersen E., Koch A.E., Woods J.M., Haines G.K., and Ivashkiv L.B. Nat. Immunol. 3 (2002) 859
25. Begitt A., Meyer T., van Rossum M., and Vinkemeier U. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 10,418
26. Kröger A., Köster M., Schroeder K., Hauser H., and Mueller P.P. J. Interferon Cytokine Res. 22 (2002) 5
27. Wormald S., Zhang J.G., Krebs D.L., Mielke L.A., Silver J., Alexander W.S., Speed T.P., Nicola N.A., and Hilton D.J. J. Biol. Chem. 281 (2006) 11,135
28. Endo T.A., Masuhara M., Yokouchi M., Suzuki R., Sakamoto H., Mitsui K., Matsumoto A., Tanimura S., Ohtsubo M., Misawa H., Miyazaki T., Leonor N., Taniguchi T., Fujita T., Kanakura Y., Komiya S., and Yoshimura A. Nature 387 (1997) 921
29. Hu X., Herrero C., Li W.P., Antoniv T.T., Falck-Pedersen E., Koch A.E., Woods J.M., Haines G.K., and Ivashkiv L.B. Nat. Immunol. 3 (2002) 859
30. Yang J., and Stark G.R. Cell Res. 18 (2008) 443
31. Levy D.E., and Darnell Jr. J.E. Nat. Rev. Mol. Cell Biol. 3 (2002) 651
32. St. Beirer, Mathematical modelling of the Jak/Stat1 signal transduction pathway, Logos Verlag Berlin GmbH, Berlin 2007.
33. Meyer T., Begitt A., Lödige I., van Rossum M., and Vinkemeier U. EMBO J. 21 (2002) 21,344
34. Meyer T., Marg A., Lemke P., Wiesner B., and Vinkemeier U. Genes Dev. 17 (2003) 1992
35. Swameye I., Muller T.G., Timmer J., Sandra O., and Klingmuller U. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 1028
36. MacDonald N. Biological delay systems: linear stability theory (2003), Cambridge University Press, Cambridge
37. Rodriguez-Fernandez M., Egea J.A., and Banga J.R. BMC Bioinformatics 7 (2006) 483
38. Schmidt H., and Jirstrand M. Bioinformatics 22 (2006) 514
39. Schilling M., Maiwald T., Bohl S., Kollmann M., Kreutz C., Timmer J., and Klingmüller U. FEBS J. 272 (2005) 6400