Studies on the lipase induced degradation of lipid based drug delivery systems

Journal of Controlled Release

Volumn 140, Issue 1, 2009, Pages 27-33

  Schwab, Martin ^a   Sax, Gerhard ^a   Schulze, Sandra ^a   Winter, Gerhard ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Biodegradation; Erosion; Extrudates, Implants; Lipid based depot systems

Indexed keywords

BIODEGRADATION PROCESS; DEGRADATION PROCESS; DEGRADATION PRODUCTS; DERIVATIZATIONS; DRUG DELIVERY SYSTEM; EXTRUDATES; EXTRUDATES, IMPLANTS; FREE FATTY ACID; IN-VITRO; IN-VIVO; IN-VIVO EXPERIMENTS; INDUCED DEGRADATION; LIPID MATRIX; LIPID PARTICLES; LONG TERM; MICRO-PARTICLES; RP-HPLC; SURFACE DEGRADATION;

BIOCHEMISTRY; BIODEGRADATION; DRUG DELIVERY; FATTY ACIDS; FLOOD CONTROL; LIPASES; MICROBIOLOGY;

DEGRADATION;

FATTY ACID; LIPID; SOLVENT; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE;

ADSORPTION; ARTICLE; BIODEGRADATION; COMPRESSION; DERIVATIZATION; DISPERSION; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; ENZYME ASSAY; EVAPORATION; EXTRACTION; IN VITRO STUDY; MELTING POINT; PARTICLE SIZE; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCANNING ELECTRON MICROSCOPY;

ANIMALS; BEETLES; BUFFERS; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HYDROGEN-ION CONCENTRATION; LIPASE; LIPID METABOLISM; LIPIDS; NANOPARTICLES; PARTICLE SIZE; PHOSPHATES; PSEUDOMONAS; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE; TRIGLYCERIDES;

EID: 70349983345     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.07.008     Document Type: Article

References (36)

1. Sullivan M.F., Ruemmler P.S., and Kalkwarf D.R. Sustained administration of cyclazocine for antagonism of morphine. Drug and Alcohol Dependence 1 6 (1976) 415-428
2. Joseph A.A., Hill J.L.J., Patel S., and Kincl A. Sustained-release hormonal preparations XV: release of progesterone from cholesterol pellets. Journal of Pharmaceutical Sciences 66 4 (1977) 490-493
3. Reithmeier H., Herrmann J., and Göpferich A. Lipid microparticles as a parenteral controlled release device for peptides. Journal of Controlled Release 73 2-3 (2001) 339-350
4. Vogelhuber W., Magni E., Gazzaniga A., and Gopferich A. Monolithic glyceryl trimyristate matrices for parenteral drug release applications. European Journal of Pharmaceutics and Biopharmaceutics 55 (2003) 133-138
5. Mohl S., and Winter G. Continuous release of rh-interferon [alpha]-2a from triglyceride matrices. Journal of Controlled Release 97 1 (2004) 67-78
6. Mohl S., and Winter G. Continuous release of rh-interferon Î ± -2a from triglyceride implants: storage stability of the dosage forms. Pharmaceutical Development and Technology 11 1 (2006) 103-110
7. Appel B., Maschke A., Weiser B., Sarhan H., Englert C., Angele P., Blunk T., and G?pferich A. Lipidic implants for controlled release of bioactive insulin: effects on cartilage engineered in vitro. International journal of Pharmaceutics 314 2 (2006) 170-178
8. Guse C., Koennings S., Maschke A., Hacker M., Becker C., Schreiner S., Blunk T., Spruss T., and Goepferich A. Biocompatibility and erosion behavior of implants made of triglycerides and blends with cholesterol and phospholipids. International Journal of Pharmaceutics 314 2 (2006) 153-160
9. Schwab M., Kessler B., Wolf E., Jordan G., Mohl S., and Winter G. Correlation of in vivo and in vitro release data for rh-INF[alpha] lipid implants. European Journal of Pharmaceutics and Biopharmaceutics 70 2 (2008) 690-694
10. Large V., Arner P., Reynisdottir S., Grober J., Van Harmelen V., Holm C., and Langin D. Hormone-sensitive lipase expression and activity in relation to lipolysis in human fat cells. Journal of Lipid Research 39 8 (1998) 1688-1695
11. Frayn K.N., Langin D., Holm C., and Belfrage P. Hormone-sensitive lipase: quantitation of enzyme activity and mRNA level in small biopsies of human adipose tissue. Clinica Chimica Acta 216 1-2 (1993) 183-189
12. Ruge T., Sukonina V., Myrnas T., Lundgren M., Eriksson J.W., and Olivecrona G. Lipoprotein lipase activity/mass ratio is higher in omental than in subcutaneous adipose tissue. European Journal of Clinical Investigation 36 1 (2006) 16-21
13. Richelsen B., Pedersen S.B., Kristensen K., Børglum J.D., Nørrelund H., Christiansen J.S., and Jørgensen J.O.L. Regulation of lipoprotein lipase and hormone-sensitive lipase activity and gene expression in adipose and muscle tissue by growth hormone treatment during weight loss in obese patients. Metabolism 49 7 (2000) 906-911
14. Kobayashi J., Kusunoki M., Murase Y., Kawashiri M., Higashikata T., Miwa K., Katsuda S., Takata M., Asano A., Nohara A., Inazu A., and Mabuchi H. Relationship of lipoprotein lipase and hepatic triacylglycerol lipase activity to serum adiponectin levels in Japanese hyperlipidemic men. Hormone and Metabolic Research 8 (2005) 505-509
15. Thörne A.Å., W., Carneheim C., Olivecrona T., and Nordenström J. Influence of trauma on plasma elimination of exogenous fat and on lipoprotein lipase activity and mass. Clinical Nutrition 24 1 (2005) 66-74
16. Persson B., and Hood B. Characterization of lipoprotein lipase activity eluted from human adipose tissue. Atherosclerosis 12 2 (1970) 241-251
17. Khoo J.C., Fong W.W., and Steinberg D. Activation of hormone-sensitive lipase from human adipose tissue by cyclic AMP-dependent protein kinase. Biochemical and Biophysical Research Communications 49 2 (1972) 407-413
18. Fielding P.E.S., V. G., and Fielding C.J. Cardiovasc., lipoprotein lipase. Properties of the enzyme isolated from post-heparin plasma. Cardiovasc. Res. Inst., Univ. California, San Francisco, CA, USA. Biochemistry 13 21 (1974)
19. Cheng C.F., Bensadoun A., Bersot T., Hsu J.S., and Melford K.H. Purification and characterization of human lipoprotein lipase and hepatic triglyceride lipase. Reactivity with monoclonal antibodies to hepatic triglyceride lipase. Journal of Biological Chemistry 260 19 (1985) 10720-10727
20. Iverius P.H., and Brunzell J.D. Human adipose tissue lipoprotein lipase: changes with feeding and relation to postheparin plasma enzyme. American Journal of Physiology: Endocrinology and Metabolism 249 1 (1985) E107-114
21. Hayashi R., Tajima S., and Yamamoto A. Purification and characterization of lipoprotein lipase from human postheparin plasma and its comparison with purified bovine milk lipoprotein lipase. Journal of Biochemistry 100 2 (1986) 319-331
22. Chakrabarty K., Radhakrishnan J., Sharifi R., Mozes M.F., Manaligod J.R., and Jeffay H. Lipogenic activity and brown fat content of human perirenal adipose tissue. Clinical Biochemistry 21 4 (1988) 249-254
23. Yeaman S.J., Smith G.M., Jepson C.A., Wood S.L., and Emmison N. The multifunctional role of hormone-sensitive lipase in lipid metabolism. Advances in Enzyme Regulation 34 (1994) 355-370
24. Bodmeier R., Wang J., and Bhagwatwar H. Process and formulation variables in the preparation of wax microparticles by a melt dispersion technique. II. W/O/W multiple emulsion technique for water-soluble drugs. Journal of Microencapsulation 9 1 (1992) 99-107
25. Dole V.P.M., and Hans. Microdetermination of long-chain fatty acids in plasma and tissues. Journal of Biological Chemistry 235 (1960) 2595-2599
26. Wood R., and Lee T. High-performance liquid chromatography of fatty acids: quantitative analysis of saturated, monoenoic, polyenoic and geometrical isomers. Journal of Chromatography A 254 (1983) 237-246
27. Brockman T.T.A.H.L. Regulation of carboxylester lipase adsorption to surfaces. 2. Physical state specificity. Biochemistry 26 25 (1987)
28. Posner I., and DeSanctis J. Kinetics of product inhibition and mechanisms of lipoprotein lipase activation by apolipoprotein C-II. Biochemistry 26 12 (1987) 3711-3717
29. Reis P., Holmberg K., Miller R., Kragel J., Grigoriev D.O., Leser M.E., and Watzke H.J. Competition between lipases and monoglycerides at interfaces. Langmuir 24 14 (2008) 7400-7407
30. Dahim M., and Brockman H. How colipase-fatty acid interactions mediate adsorption of pancreatic lipase to interfaces†. Biochemistry 37 23 (1998) 8369-8377
31. Reis P., Miller R., KraÌgel J., Leser M., Fainerman V.B., Watzke H., and Holmberg K. Lipases at interfaces: unique interfacial properties as globular proteins. Langmuir 24 13 (2008) 6812-6819
32. Nair L.S., and Laurencin C.T. Biodegradable polymers as biomaterials. Progress in Polymer Science 32 8-9 (2007) 762-798
33. Pitt C.G., Hendren R.W., Schindler A., and Woodward S.C. The enzymatic surface erosion of aliphatic polyesters. Journal of Controlled Release 1 1 (1984) 3-14
34. Zhang Z., Zou S., Vancso G.J., Grijpma D.W., and Feijen J. Enzymatic surface erosion of poly(trimethylene carbonate) films studied by atomic force microscopy. Biomacromolecules 6 6 (2005) 3404-3409
35. Brzozowski A.M., Derewenda U., Derewenda Z.S., Dodson G.G., Lawson D.M., Turkenburg J.P., Bjorkling F., Huge-Jensen B., Patkar S.A., and Thim L. A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex. Nature 351 6326 (1991) 491-494
36. Reis P., Holmberg K., Miller R., KraÌgel J., Grigoriev D.O., Leser M.E., and Watzke H.J. Competition between lipases and monoglycerides at interfaces. Langmuir 24 14 (2008) 7400-7407