Mixing and hydrodynamic analysis of a droplet in a planar serpentine micromixer

Microfluidics and Nanofluidics

Volumn 7, Issue 4, 2009, Pages 545-557

  Tung, Kai Yang ^a   Li, Chih Chieh ^a   Yang, Jing Tang ^b  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Hydrodynamics; Mixing; Planar serpentine micromixer (PSM); Probability distribution function (PDF)

Indexed keywords

CHAOTIC MIXING; CONCENTRATION OF; CROSS SECTION; DIFFUSION EFFECTS; HYDRODYNAMIC ANALYSIS; MICRO MIXERS; MICRO PARTICLE IMAGE VELOCIMETRY; MIXING EFFICIENCY; MIXING INDEX; NON-INTRUSIVE DIAGNOSTICS; NUMERICAL SIMULATION; PLANAR SERPENTINE MICROMIXER (PSM); PROBABILITY DISTRIBUTION FUNCTION (PDF); RECIRCULATIONS; ROBUST SOLUTIONS; SIMULATED FLUIDS; SPECIFIC DESIGN; VORTICITY FIELD;

COMPUTATIONAL FLUID DYNAMICS; COMPUTER SIMULATION; DISTRIBUTION FUNCTIONS; DROP BREAKUP; DROP FORMATION; FLOW VISUALIZATION; FLUIDS; HYDRODYNAMICS; MIXERS (MACHINERY); MIXING; PROBABILITY; PROBABILITY DENSITY FUNCTION; PULSE MODULATION; SERPENTINE; SILICATE MINERALS; VORTICITY;

FLUID DYNAMICS;

EID: 70349978973     PISSN: 16134982     EISSN: 16134990     Source Type: Journal    
DOI: 10.1007/s10404-009-0415-8     Document Type: Article

References (29)

1. Bitsch L, Olesen LH, Westergaard CH, Bruus H, Klank H, Kutter JP (2005) Micro particle-image velocimetry of bead suspensions and blood flows. Exp Fluids 39:505-511
2. Brackbill JU, Kothe DB, Zemach C (1992) A continuum method for modeling surface tension. J Comp Phys 100:335-354
3. Bringer MR, Gerdts CJ, Song H, Tice JD, Ismagilov RF (2004) Microfluidic systems for chemical kinetics that rely on chaotic mixing in droplets. Philos Trans R Soc Lond A 362:1087-1104
4. Chabreyrie R, Vainchtein D, Chandre C, Singh P, Aubry N (2008) Tailored mixing inside a translating drop. Phys Rev E 77:036314
5. Chen JK, Yang RJ (2008) Vortex generation in electroosmotic flow passing through sharp corners. Microfluid Nanofluid. doi: 10.1007/ s10404-008-0307-3
6. Chung CK, Shih TR (2007) A rhombic micromixer with asymmetrical flow for enhancing mixing. J Micromech Microeng 17:2495-2504
7. Harries N, Burns JR, Barrow DA, Ramshaw C (2003) A numerical model for segmented flow in a microreactor. Int J Heat Mass Transf 46:3313-3322
8. Hirt CW, Nichols BD (1981) Volume of fluid (VOF) method for the dynamics of free boundaries. J Comput Phys 39:201-225
9. Hosokawa K, Fujii T, Endo I (1999) Droplet-based nano/picoliter mixer using hydrophobic microcapillary vent. In: Proceedings of the IEEE international workshop on micro electromechanical system, Piscataway, NJ, USA, pp 388-393
10. Kashid MN, Gerlach I, Goetz S, Franzke J, Acker JF, Platte F, Agar DW, Turek S (2005) Internal circulation within the liquid slugs of a liquid-liquid slug-flow capillary microreactor. Ind Eng Chem Res 44:5003-5010
11. King C, Walsh E, Grimes R (2007) PIV measurements of flow within plugs in a microchannel. Microfluid Nanofluid 3:463-472
12. Kinoshita H, Kaneda S, Fujii T, Oshima (2007) Three-dimensional measurement and visualization of internal flow of a moving droplet using confocal micro-PIV. Lab Chip 7:338-346
13. Kothe DB, Rider WJ, Mosso SJ, Brock JS (1996) Volume tracking of interfaces having surface tension in two and three dimension. In: Proceedings of the 34th aerospace science meeting exhibition AIAA-96-0859, pp 1-24
14. Liau A, Karnik R, Majumdar A, Cate JHD (2005) Mixing crowded biological solutions in milliseconds. Anal Chem 77:7618-7625
15. Meinhart CD, Wereley ST, Gray MHB (2000) Volume illumination for two-dimensional particle image velocimetry. Meas Sci Technol 11:809-814
16. Muradoglu M, Stone HA (2005) Mixing in a drop moving through a serpentine channel: A computational study. Phys Fluids 17:073305
17. Paik P, Pamula VK, Fair RB (2003) Rapid droplet mixers for digital microfluidic systems. Lab Chip 3:253-259
18. Richard S, Ming TK, Leslie YY, Friend JR (2008) Particle concentration and mixing in microdrops driven by focused surface acoustic waves. J Appl Phys 104:014910
19. Rider WJ, Kothe DB (1995) Stretching and tearing interface tracing methods. In: Proceedings of the 33rd aerospace science meeting exhibition AIAA-95-1717, pp 1-11
20. Santiago JG, Wereley ST, Meinhart CD, Beebe DJ, Adrian RJ (1998) A particle image velocimetry system for microfluidics. Exp Fluids 25:316-319
21. Sarrazin F, Bonometti T, Loubière K, Prat L, Gourdon C, Magnaudet J (2006) Experimental and numerical study of droplet hydrodynamics in microchannels. AIChE J 52(12):4061-4070
22. Sarrazin F, Bonometti T, Prat L, Gourdon C, Magnaudet J (2008) Hydrodynamic structures of droplets engineered in rectangular micro-channels. Microfluid Nanofluid 5:131-137
23. Song H, Bringer MR, Tice JD, Gerdts CJ, Ismagilov RF (2003a) Experimental test of scaling of mixing by chaotic advection in droplets moving through microfluidic channels. Appl Phys Lett 83:4664-4666
24. Song H, Tice JD, Ismagilov RF (2003b) A microfluidic system for controlling reaction networks in time. Angew Chem Int Ed 42:768-772
25. Stremler MA (2008) Mixing measures. In: Li D (ed) Encyclopedia of microfluidics and nanofluidics. Springer, Berlin
26. Teh SY, Lin R, Hung LH, Lee AP (2008) Droplet microfluidics. Lab Chip 8:198-220
27. Tice JD, Lyon AD, Ismagilov RF (2004) Effects of viscosity on droplet formation and mixing in microfluidic channels. Anal Chim Acta 507:73-77
28. Wang L, Yang JT (2006) An overlapping criss-cross micromixer using chaotic mixing principles. J Micromech Microeng 16:2684-2691
29. Yang JT, Huang KJ, Lin YC (2005) Geometric effects on fluid mixing in a passive grooved micromixer. Lab Chip 5:1140-1147