IFRD1 modulates disease severity in cystic fibrosis through the regulation of neutrophil effector function

Clinical Genetics

Volumn 76, Issue 2, 2009, Pages 148-149

  Ehrnhoefer, D E ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE 1; PROTEIN IFRD1; TRANSCRIPTION FACTOR; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

CELL FUNCTION; CYSTIC FIBROSIS; DISEASE MODEL; DISEASE SEVERITY; FOLLOW UP; GENE FREQUENCY; GENE IDENTIFICATION; GENOTYPE; HUMAN; INFLAMMATION; LUNG DISEASE; LUNG INFECTION; MORBIDITY; MORTALITY; NEUTROPHIL; NONHUMAN; NOTE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 70349978815     PISSN: 00099163     EISSN: 13990004     Source Type: Journal    
DOI: 10.1111/j.1399-0004.2009.01247_2.x     Document Type: Note

References (8)

1. Proesmans M, Vermeulen F, De Boeck K. What's new in cystic fibrosis? From treating symptoms to correction of the basic defect. Eur J Pediatr 2008, 167(8):839-849.
2. Kerem E, Corey M, Kerem BS. The relation between genotype and phenotype in cystic fibrosis-analysis of the most common mutation (delta F508). N Engl J Med 1990, 323(22):1517-1522.
3. Drumm ML, Konstan MW, Schluchter MD. Genetic modifiers of lung disease in cystic fibrosis. N Engl J Med 2005, 353(14):1443-1453.
4. Vadivelu SK, Kurzbauer B, Dieplinger B. Muscle regeneration and myogenic differentiation defects in mice lacking TIS7. Mol Cell Biol 2004, 24(8):3514-3525.
5. Vietor I, Huber LA. Role of TIS7 family of transcriptional regulators in differentiation and regeneration. Differentiation 2007, 75(9):891-897.
6. Anrather J, Racchumi G, Iadecola C. NF-kappaB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox. J Biol Chem 2006, 281(9):5657-5667.
7. Riedemann NC, Guo RF, Bernacki KD. Regulation by C5a of neutrophil activation during sepsis. Immunity 2003, 19(2):193-202.
8. Ashburner BP, Westerheide SD, Baldwin AS. The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol Cell Biol 2001, 21(20):7065-7077.