Analysis of the plasma peptidome from pancreas cancer patients connects a peptide in plasma to overexpression of the parent protein in tumors

Journal of Proteome Research

Volumn 8, Issue 10, 2009, Pages 4722-4731

  Antwi, Kwasi ^a   Hostetter, Galen ^b   Demeure, Michael J ^b   Katchman, Benjamin A ^a   Decker, G Anton ^c   Ruiz, Yvette ^a   Sielaff, Timothy D ^d   Koep, Lawrence J ^e   Lake, Douglas F ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

^b TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^c MAYO CLINIC   (United States)

^d Virginia Piper Cancer Institute   (United States)

^e BANNER GOOD SAMARITAN MEDICAL CENTER   (United States)

Author keywords

Collision activated dissociation; Immunohistochemistry; Liquid chromatography; Pancreatic cancer; Peptidome; Plasma; Tandem mass spectrometry; Western blot

Indexed keywords

PROTEIN; QUIESCIN SULFHYDRYL OXIDASE 1; UNCLASSIFIED DRUG;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; CANCER PATIENT; CONTROLLED STUDY; DUCTAL ADENOCARCINOMA OF THE PANCREAS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTRADUCTAL PAPILLARY MUCINOUS TUMOR; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SYNTHESIS; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING;

ADOLESCENT; ADULT; BLOTTING, WESTERN; CARCINOMA, DUCTAL; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; PEPTIDES; PROTEIN STABILITY; PROTEOME; TANDEM MASS SPECTROMETRY; THIOREDOXINS;

EID: 70349976310     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr900414f     Document Type: Article

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