Quantification and prediction of skin pharmacokinetics of amoxicillin and cefuroxime

Biopharmaceutics and Drug Disposition

Volumn 30, Issue 6, 2009, Pages 281-293

  Shukla, Chinmay ^a   Patel, Vishal ^a   Juluru, Ravi ^a   Stagni, Grazia ^a  

^a LONG ISLAND UNIVERSITY   (United States)

Author keywords

Antibiotics; Microdialysis; Modeling; Pharmacokinetics; Prediction

Indexed keywords

AMOXICILLIN; CEFUROXIME;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; EXPERIMENTAL RABBIT; FEMALE; MAXIMUM PLASMA CONCENTRATION; MICRODIALYSIS; NONHUMAN; QUANTITATIVE ANALYSIS; SKIN; TARGET ORGAN; TIME TO MAXIMUM PLASMA CONCENTRATION; TISSUE DISTRIBUTION;

AMOXICILLIN; ANIMALS; CEFUROXIME; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROSS-OVER STUDIES; DRUG EVALUATION, PRECLINICAL; FEMALE; PREDICTIVE VALUE OF TESTS; RABBITS; SKIN;

EID: 70349971950     PISSN: 01422782     EISSN: 1099081X     Source Type: Journal    
DOI: 10.1002/bdd.658     Document Type: Article

References (29)

1. Jacobs MR, Jones RN, Giordano PA. Oral betalactams applied to uncomplicated infections of skin and skin structures. Diagn Microbiol Infect Dis 2007; 57: S55-S65.
2. Schuck EL, Derendorf H. Pharmacokinetic/pharmacodynamic evaluation of anti-infective agents. Expert Rev Anti Infect Ther 2005; 3: 361-373. DOI: 10.1586/14787210.3.3.361.
3. Stagni G, Shukla C. Pharmacokinetics of methotrexate in rabbit skin and plasma after iv-bolus and iontophoretic administrations. J Control Release 2003; 93: 283-292.
4. Chaurasia CS, Muller M, Bashaw ED, et al. AAPSFDA workshop white paper: microdialysis principles, application and regulatory perspectives. Pharm Res 2007; 24: 1014-1025. DOI: 10.1007/ s11095-006-9206-z.
5. Muller M, dela Pena A, Derendorf H. Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: distribution in tissue. Antimicrob Agents Chemother 2004; 48: 1441-1453.
6. Bossi P, Tegnell A, Baka A, et al. Bichat guidelines for the clinical management of anthrax and bioterrorism-related anthrax. Euro Surveill 2004; 9: E3-E4.
7. Swartz MN. Recognition and management of anthrax-an update. N Engl J Med 2001; 345: 1621-1626.
8. O'Brien KK, Higdon ML, Halverson JJ. Recognition and management of bioterrorism infections. Am Fam Physician 2003; 67: 1927-1934.
9. Jacobs RF, Brown WD, Chartrand S, et al. Evaluation of cefuroxime axetil and cefadroxil suspensions for treatment of pediatric skin infections. Antimicrob Agents Chemother 1992; 36: 1614-1618.
10. Parish LC, Cocchetto DM, Werner K, Jungkind DL, Witkowski J. Cefuroxime axetil in the treatment of cutaneous infections. Int J Dermatol 1987; 26: 389-393.
11. Erah PO, Barrett DA, Shaw PN. Reversed-phase high-performance liquid chromatographic assay methods for the analysis of a range of penicillins in in vitro permeation studies. J Chromatogr B Biomed Sci Appl 1998; 705: 63-69.
12. Tsai TH, Cheng FC, Chen KC, Chen YF, Chen CF. Simultaneous measurement of cefuroxime in rat blood and brain by microdialysis and microbore liquid chromatography. Application to pharmacokinetics. J Chromatogr B Biomed Sci Appl 1999; 735: 25-31.
13. FDA. Guidance for Industry: Bioanalytical Method Validation. www.fda.gov/cder/guidance/4252fnl.pdf, 2001.
14. Stagni G, O'Donnell D, Liu YJ, Kellogg Jr DL, Shepherd AM. Iontophoretic current and intradermal microdialysis recovery in humans. J Pharmacol Toxicol Methods 1999; 41: 49-54.
15. Du X, Li C, Sun HK, Nightingale CH, Nicolau DP. A sensitive assay of amoxicillin in mouse serum and broncho-alveolar lavage fluid by liquid-liquid extraction and reversed-phase HPLC. J Pharm Biomed Anal 2005; 39: 648-652.
16. Al-Said MS, Al-Khamis KI, Niazy EM, et al. Bioequivalence evaluation of two brands of cefuroxime 500mg tablets (Cefuzime and Zinnat) in healthy human volunteers. Biopharm Drug Dispos 2000; 21: 205-210. DOI: 10.1002/bdd.237 [pii].
17. Stagni G, O'Donnell D, Liu YJ, Kellogg DL, Morgan T, Shepherd AM. Intradermal microdialysis: kinetics of iontophoretically delivered propranolol in forearm dermis. J Control Release 2000; 63: 331-339.
18. Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications. Swedish Pharmaceutical Press: Stockholm, Sweden, 2006.
19. Athamna A, Massalha M, Athamna M, et al. In vitro susceptibility of Bacillus anthracis to various antibacterial agents and their time-kill activity. J Antimicrob Chemother 2004; 53: 247-251.
20. The FDA Website. http://www.fda.gov/medwatch/SAFETY/2004/jun_PI/ CefUROXime%20for%20-Injection_PI.pdf, [29 Januaury 2009].
21. Ergin C, Ulker D, Haluk G, Ahmet Derya A, Erdal I. Antibiotic susceptibility of Streptococcus pyogenes strains isolated from throat cultures of children with tonsillopharyngitis. J Ankara Med School 2003; 25: 15-20.
22. Rowland M, Tozer TN. Clinical Pharmacokinetics. Lippincott Williams & Wilkins: Philadelphia, Pennsylvania, 1995.
23. Bonate PL. Pharmacokinetic- Pharmacodynamic Modeling and Simulation. Springer Science: New York, NY, 2006.
24. Geldof M, Freijer J, van Beijsterveldt L, Danhof M. Pharmacokinetic modeling of non-linear brain distribution of fluvoxamine in the rat. Pharm Res 2008; 25: 792-804. DOI: 10.1007/ s11095-007-9390-5.
25. de Lange EC, de Boer AG, Breimer DD. Methodological issues in microdialysis sampling for pharmacokinetic studies. Adv Drug Deliv Rev 2000; 45: 125-148.
26. Andes D, Craig WA. Animal model pharmacokinetics and pharmacodynamics: a critical review. Int J Antimicrob Agents 2002; 19: 261-268. S0924857902000225 [pii].
27. Marchand S, Chenel M, Lamarche I, Couet W. Pharmacokinetic modeling of free amoxicillin concentrations in rat muscle extracellular fluids determined by microdialysis. Antimicrob Agents Chemother 2005; 49: 3702-3706.
28. Huang Y, Ji P, Inano A, Yang Z, Giebink GS, Sawchuk RJ. Microdialysis studies of the middle ear distribution kinetics of amoxicillin in the awake chinchilla. J Pharm Sci 2001; 90: 2088-2098.
29. Mand'ak J, Pojar M, Malakova J, Lonsk V, Palicka V, Zivny P. Tissue and plasma concentrations of cephuroxime during cardiac surgery in cardiopulmonary bypass-a microdialysis study. Perfusion 2007; 22: 129-136.