Simultaneous improvement of catalytic activity and thermal stability of tyrosine phenol-lyase by directed evolution

FEBS Journal

Volumn 276, Issue 21, 2009, Pages 6187-6194

  Rha, Eugene ^a   Kim, Sujin ^a   Choi, Su Lim ^a   Hong, Seung Pyo ^b   Sung, Moon Hee ^b   Song, Jae J ^a,c   Lee, Seung Goo ^a,c  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Bioleaders Corporation   (South Korea)

^c NONE   (South Korea)

Author keywords

N terminal arm; Protein engineering; Structural relevance; Symbiobacterium toebii; Tyrosine phenol lyase

Indexed keywords

DIMER; TYROSINE PHENOL LYASE;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIUM; CATALYSIS; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME STABILITY; MUTAGENESIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FOLDING; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SYMBIOBACTERIUM TOEBII; THERMOSTABILITY;

ACTINOBACTERIA; AMINO ACID SEQUENCE; CATALYSIS; DIRECTED MOLECULAR EVOLUTION; ENZYME STABILITY; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PROTEIN CONFORMATION; TYROSINE PHENOL-LYASE;

SYMBIOBACTERIUM TOEBII;

EID: 70349961604     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07322.x     Document Type: Article

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