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Volumn 101, Issue 8, 2009, Pages 1298-1306

Cytokeratins 18 and 8 are poor prognostic markers in patients with squamous cell carcinoma of the oesophagus

Author keywords

Cytokeratin18 (CK18); Cytokeratin8 (CK8); Immunohistochemistry (IHC); Oesophageal squamous cell carcinoma (OSCC); Quantitative reverse transcription polymerase chain reaction (RTPCR)

Indexed keywords

CYTOKERATIN 18; CYTOKERATIN 8;

EID: 70349952519     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6605313     Document Type: Article
Times cited : (71)

References (52)
  • 3
    • 0021357008 scopus 로고
    • Aberrant expression of keratin proteins and cross-linked envelopes in human esophageal carcinomas
    • Banks-Schlegel SP, Harris CC (1984) Aberrant expression of keratin proteins and cross-linked envelopes in human esophageal carcinomas. Cancer Res 44: 1153-1157
    • (1984) Cancer Res , vol.44 , pp. 1153-1157
    • Banks-Schlegel, S.P.1    Harris, C.C.2
  • 4
    • 0025862171 scopus 로고
    • A series of 14 new monoclonal antibodies to keratins: Characterization and value in diagnostic histopathology
    • Bartek J, Vojtesek B, Staskova Z, Bartkova J, Kerekes Z, Rejthar A, Kovarik J (1991) A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology. J Pathol 164: 215-224
    • (1991) J Pathol , vol.164 , pp. 215-224
    • Bartek, J.1    Vojtesek, B.2    Staskova, Z.3    Bartkova, J.4    Kerekes, Z.5    Rejthar, A.6    Kovarik, J.7
  • 6
    • 22944492443 scopus 로고    scopus 로고
    • Transfection of keratin 18 gene in human breast cancer cells causes induction of adhesion proteins and dramatic regression of malignancy in vitro and in vivo
    • Buhler H, Schaller G (2005) Transfection of keratin 18 gene in human breast cancer cells causes induction of adhesion proteins and dramatic regression of malignancy in vitro and in vivo. Mol Cancer Res 3: 365-371
    • (2005) Mol Cancer Res , vol.3 , pp. 365-371
    • Buhler, H.1    Schaller, G.2
  • 7
    • 0036090767 scopus 로고    scopus 로고
    • Keratin expression in human tissues and neoplasms
    • Chu PG, Weiss LM (2002a) Keratin expression in human tissues and neoplasms. Histopathology 40: 403-439
    • (2002) Histopathology , vol.40 , pp. 403-439
    • Chu, P.G.1    Weiss, L.M.2
  • 8
    • 0036143244 scopus 로고    scopus 로고
    • Expression of cytokeratin 5/6 in epithelial neoplasms: An immunohistochemical study of 509 cases
    • Chu PG, Weiss LM (2002b) Expression of cytokeratin 5/6 in epithelial neoplasms: an immunohistochemical study of 509 cases. Mod Pathol 15: 6-10
    • (2002) Mod Pathol , vol.15 , pp. 6-10
    • Chu, P.G.1    Weiss, L.M.2
  • 9
    • 0027211896 scopus 로고
    • Expression of complete keratin filaments in mouse L cells augments cell migration and invasion
    • Chu YW, Runyan RB, Oshima RG, Hendrix MJ (1993) Expression of complete keratin filaments in mouse L cells augments cell migration and invasion. Proc Natl Acad Sci USA 90: 4261-4265
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4261-4265
    • Chu, Y.W.1    Runyan, R.B.2    Oshima, R.G.3    Hendrix, M.J.4
  • 10
    • 0030052431 scopus 로고    scopus 로고
    • Experimental coexpression of vimentin and keratin intermediate filaments in human melanoma cells augments motility
    • Chu YW, Seftor EA, Romer LH, Hendrix MJ (1996) Experimental coexpression of vimentin and keratin intermediate filaments in human melanoma cells augments motility. Am J Pathol 148: 63-69
    • (1996) Am J Pathol , vol.148 , pp. 63-69
    • Chu, Y.W.1    Seftor, E.A.2    Romer, L.H.3    Hendrix, M.J.4
  • 14
    • 0021327652 scopus 로고
    • Immunohis-tochemical distinction of human carcinomas by cytokeratin typing with monoclonal antibodies
    • Debus E, Moll R, Franke WW, Weber K, Osborn M (1984) Immunohis-tochemical distinction of human carcinomas by cytokeratin typing with monoclonal antibodies. Am J Pathol 114: 121-130
    • (1984) Am J Pathol , vol.114 , pp. 121-130
    • Debus, E.1    Moll, R.2    Franke, W.W.3    Weber, K.4    Osborn, M.5
  • 18
    • 33751575293 scopus 로고    scopus 로고
    • Detection of cancer cells disseminated in bone marrow using real-time quantitative RT-PCR of CEA, CK19, and CK20 mRNA in patients with gastric cancer
    • Fujita Y, Terashima M, Hoshino Y, Ohtani S, Kashimura S, Kanzaki N, Osuka F, Kogure M, Gotoh M (2006) Detection of cancer cells disseminated in bone marrow using real-time quantitative RT-PCR of CEA, CK19, and CK20 mRNA in patients with gastric cancer. Gastric Cancer 9: 308-314
    • (2006) Gastric Cancer , vol.9 , pp. 308-314
    • Fujita, Y.1    Terashima, M.2    Hoshino, Y.3    Ohtani, S.4    Kashimura, S.5    Kanzaki, N.6    Osuka, F.7    Kogure, M.8    Gotoh, M.9
  • 19
    • 33645107350 scopus 로고    scopus 로고
    • CK8 correlates with malignancy in leukoplakia and carcinomas of the head and neck
    • Gires O, Mack B, Rauch J, Matthias C (2006) CK8 correlates with malignancy in leukoplakia and carcinomas of the head and neck. Biochem Biophys Res Commun 343: 252-259
    • (2006) Biochem Biophys Res Commun , vol.343 , pp. 252-259
    • Gires, O.1    MacK, B.2    Rauch, J.3    Matthias, C.4
  • 20
    • 0021958743 scopus 로고
    • Keratin expression in normal esophageal epithelium and squamous cell carcinoma of the esophagus
    • Grace MP, Kim KH, True LD, Fuchs E (1985) Keratin expression in normal esophageal epithelium and squamous cell carcinoma of the esophagus. Cancer Res 45: 841-846
    • (1985) Cancer Res , vol.45 , pp. 841-846
    • Grace, M.P.1    Kim, K.H.2    True, L.D.3    Fuchs, E.4
  • 22
    • 0034907507 scopus 로고    scopus 로고
    • Genes for intermediate filament proteins and the draft sequence of the human genome: Novel keratin genes and a surprisingly high number of pseudogenes related to keratin genes 8 and 18
    • Hesse M, Magin TM, Weber K (2001) Genes for intermediate filament proteins and the draft sequence of the human genome: novel keratin genes and a surprisingly high number of pseudogenes related to keratin genes 8 and 18. J Cell Sci 114: 2569-2575
    • (2001) J Cell Sci , vol.114 , pp. 2569-2575
    • Hesse, M.1    Magin, T.M.2    Weber, K.3
  • 23
    • 39249084368 scopus 로고    scopus 로고
    • Coordinate expression of cytokeratin 8 and cytokeratin 17 immunohistochemical staining in cervical intraepithelial neoplasia and cervical squamous cell carcinoma: An immunohistochemical analysis and review of the literature
    • Ikeda K, Tate G, Suzuki T, Mitsuya T (2008) Coordinate expression of cytokeratin 8 and cytokeratin 17 immunohistochemical staining in cervical intraepithelial neoplasia and cervical squamous cell carcinoma: an immunohistochemical analysis and review of the literature. Gynecol Oncol 108: 598-602
    • (2008) Gynecol Oncol , vol.108 , pp. 598-602
    • Ikeda, K.1    Tate, G.2    Suzuki, T.3    Mitsuya, T.4
  • 25
    • 0642280671 scopus 로고    scopus 로고
    • Neoadjuvant treatment for resectable cancer of the esophagus and the gastroesophageal junction: A meta-analysis of randomized clinical trials
    • Kaklamanos IG, Walker GR, Ferry K, Franceschi D, Livingstone AS (2003) Neoadjuvant treatment for resectable cancer of the esophagus and the gastroesophageal junction: a meta-analysis of randomized clinical trials. Ann Surg Oncol 10: 754-761
    • (2003) Ann Surg Oncol , vol.10 , pp. 754-761
    • Kaklamanos, I.G.1    Walker, G.R.2    Ferry, K.3    Franceschi, D.4    Livingstone, A.S.5
  • 26
    • 2442636422 scopus 로고    scopus 로고
    • Cytokeratin expression profile in gastric carcinomas
    • Kim MA, Lee HS, Yang HK, Kim WH (2004) Cytokeratin expression profile in gastric carcinomas. Hum Pathol 35: 576-581
    • (2004) Hum Pathol , vol.35 , pp. 576-581
    • Kim, M.A.1    Lee, H.S.2    Yang, H.K.3    Kim, W.H.4
  • 27
    • 33748917425 scopus 로고    scopus 로고
    • Cytokeratin profiles identify diagnostic signatures in colorectal cancer using multiplex analysis of tissue microarrays
    • Knosel T, Emde V, Schluns K, Schlag PM, Dietel M, Petersen I (2006) Cytokeratin profiles identify diagnostic signatures in colorectal cancer using multiplex analysis of tissue microarrays. Cell Oncol 28: 167-175
    • (2006) Cell Oncol , vol.28 , pp. 167-175
    • Knosel, T.1    Emde, V.2    Schluns, K.3    Schlag, P.M.4    Dietel, M.5    Petersen, I.6
  • 29
    • 0028999094 scopus 로고
    • Cytokeratin expression in non-neoplastic oesophageal epithelium and squamous cell carcinoma of the oesophagus
    • Lam KY, Loke SL, Shen XC, Ma LT (1995) Cytokeratin expression in non-neoplastic oesophageal epithelium and squamous cell carcinoma of the oesophagus. Virchows Arch 426: 345-349
    • (1995) Virchows Arch , vol.426 , pp. 345-349
    • Lam, K.Y.1    Loke, S.L.2    Shen, X.C.3    Ma, L.T.4
  • 30
    • 38949096078 scopus 로고    scopus 로고
    • Multipoint quantification of multimarker genes in peripheral blood and micrometastasis characteristic in peri-operative esophageal cancer patients
    • Liu Z, Jiang M, Yan F, Xu L, Zhao J, Ju H (2008) Multipoint quantification of multimarker genes in peripheral blood and micrometastasis characteristic in peri-operative esophageal cancer patients. Cancer Lett 261: 46-54
    • (2008) Cancer Lett , vol.261 , pp. 46-54
    • Liu, Z.1    Jiang, M.2    Yan, F.3    Xu, L.4    Zhao, J.5    Ju, H.6
  • 32
    • 53949111150 scopus 로고    scopus 로고
    • Use of (18)F-fluorodeoxy-glucose-positron emission tomography to evaluate responses to neo-adjuvant chemotherapy for primary tumor and lymph node metastasis in esophageal squamous cell carcinoma
    • Makino T, Doki Y, Miyata H, Yasuda T, Yamasaki M, Fujiwara Y, Takiguchi S, Higuchi I, Hatazawa J, Monden M (2008) Use of (18)F-fluorodeoxy-glucose- positron emission tomography to evaluate responses to neo-adjuvant chemotherapy for primary tumor and lymph node metastasis in esophageal squamous cell carcinoma. Surgery 144: 793-802
    • (2008) Surgery , vol.144 , pp. 793-802
    • Makino, T.1    Doki, Y.2    Miyata, H.3    Yasuda, T.4    Yamasaki, M.5    Fujiwara, Y.6    Takiguchi, S.7    Higuchi, I.8    Hatazawa, J.9    Monden, M.10
  • 35
    • 0020467073 scopus 로고
    • The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells
    • Moll R, Franke WW, Schiller DL, Geiger B, Krepler R (1982) The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31: 11-24
    • (1982) Cell , vol.31 , pp. 11-24
    • Moll, R.1    Franke, W.W.2    Schiller, D.L.3    Geiger, B.4    Krepler, R.5
  • 36
    • 0030473762 scopus 로고    scopus 로고
    • Oncogenic regulation and function of keratins 8 and 18
    • Oshima RG, Baribault H, Caulin C (1996) Oncogenic regulation and function of keratins 8 and 18. Cancer Metastasis Rev 15: 445-471
    • (1996) Cancer Metastasis Rev , vol.15 , pp. 445-471
    • Oshima, R.G.1    Baribault, H.2    Caulin, C.3
  • 37
    • 0036857269 scopus 로고    scopus 로고
    • Expression of cytokeratins 7 and 20 in primary carcinomas of the stomach and colorectum and their value in the differential diagnosis of metastatic carcinomas to the ovary
    • Park SY, Kim HS, Hong EK, Kim WH (2002) Expression of cytokeratins 7 and 20 in primary carcinomas of the stomach and colorectum and their value in the differential diagnosis of metastatic carcinomas to the ovary. Hum Pathol 33: 1078-1085
    • (2002) Hum Pathol , vol.33 , pp. 1078-1085
    • Park, S.Y.1    Kim, H.S.2    Hong, E.K.3    Kim, W.H.4
  • 38
    • 4043082812 scopus 로고    scopus 로고
    • Implications of cytokeratin 8/18 filament formation in stratified epithelial cells: Induction of transformed phenotype
    • Raul U, Sawant S, Dange P, Kalraiya R, Ingle A, Vaidya M (2004) Implications of cytokeratin 8/18 filament formation in stratified epithelial cells: induction of transformed phenotype. Int J Cancer 111: 662-668
    • (2004) Int J Cancer , vol.111 , pp. 662-668
    • Raul, U.1    Sawant, S.2    Dange, P.3    Kalraiya, R.4    Ingle, A.5    Vaidya, M.6
  • 39
    • 0025115234 scopus 로고
    • Distribution of cytokeratin polypeptides in human transitional cell carcinomas, with special emphasis on changing expression patterns during tumor progression
    • Schaafsma HE, Ramaekers FC, van Muijen GN, Lane EB, Leigh IM, Robben H, Huijsmans A, Ooms EC, Ruiter DJ (1990) Distribution of cytokeratin polypeptides in human transitional cell carcinomas, with special emphasis on changing expression patterns during tumor progression. Am J Pathol 136: 329-343
    • (1990) Am J Pathol , vol.136 , pp. 329-343
    • Schaafsma, H.E.1    Ramaekers, F.C.2    Van Muijen, G.N.3    Lane, E.B.4    Leigh, I.M.5    Robben, H.6    Huijsmans, A.7    Ooms, E.C.8    Ruiter, D.J.9
  • 41
    • 0026587005 scopus 로고
    • Intermediate filaments as differentiation markers of normal pancreas and pancreas cancer
    • Schussler MH, Skoudy A, Ramaekers F, Real FX (1992) Intermediate filaments as differentiation markers of normal pancreas and pancreas cancer. Am J Pathol 140: 559-568
    • (1992) Am J Pathol , vol.140 , pp. 559-568
    • Schussler, M.H.1    Skoudy, A.2    Ramaekers, F.3    Real, F.X.4
  • 42
    • 0038441637 scopus 로고    scopus 로고
    • Prediction of survival with squamous cell carcinoma antigen in patients with resectable esophageal squamous cell carcinoma
    • DOI 10.1067/msy.2003.139
    • Shimada H, Nabeya Y, Okazumi S, Matsubara H, Shiratori T, Gunji Y, Kobayashi S, Hayashi H, Ochiai T (2003) Prediction of survival with squamous cell carcinoma antigen in patients with resectable esophageal squamous cell carcinoma. Surgery 133: 486-494 (Pubitemid 36638220)
    • (2003) Surgery , vol.133 , Issue.5 , pp. 486-494
    • Shimada, H.1    Nabeya, Y.2    Okazumi, S.-I.3    Matsubara, H.4    Shiratori, T.5    Gunji, Y.6    Kobayashi, S.7    Hayashi, H.8    Ochiai, T.9
  • 44
    • 0032899918 scopus 로고    scopus 로고
    • Cytokeratin expression patterns in normal and malignant urothelium: A review of the biological and diagnostic implications
    • Southgate J, Harnden P, Trejdosiewicz LK (1999) Cytokeratin expression patterns in normal and malignant urothelium: a review of the biological and diagnostic implications. Histol Histopathol 14: 657-664
    • (1999) Histol Histopathol , vol.14 , pp. 657-664
    • Southgate, J.1    Harnden, P.2    Trejdosiewicz, L.K.3
  • 45
    • 0028929491 scopus 로고
    • Immunohistochemical staining patterns of keratins in normal oesophageal epithelium and carcinoma of the oesophagus
    • Takahashi H, Shikata N, Senzaki H, Shintaku M, Tsubura A (1995) Immunohistochemical staining patterns of keratins in normal oesophageal epithelium and carcinoma of the oesophagus. Histo-pathology 26: 45-50
    • (1995) Histo-pathology , vol.26 , pp. 45-50
    • Takahashi, H.1    Shikata, N.2    Senzaki, H.3    Shintaku, M.4    Tsubura, A.5
  • 46
    • 0028983214 scopus 로고
    • Immunohistochemical analysis of cytokeratin #8 as a prognostic factor in invasive breast carcinoma
    • Takei H, Iino Y, Horiguchi J, Kanoh T, Takao Y, Oyama T, Morishita Y (1995) Immunohistochemical analysis of cytokeratin #8 as a prognostic factor in invasive breast carcinoma. Anticancer Res 15: 1101-1105
    • (1995) Anticancer Res , vol.15 , pp. 1101-1105
    • Takei, H.1    Iino, Y.2    Horiguchi, J.3    Kanoh, T.4    Takao, Y.5    Oyama, T.6    Morishita, Y.7
  • 47
    • 41949119177 scopus 로고    scopus 로고
    • Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781
    • Tepper J, Krasna MJ, Niedzwiecki D, Hollis D, Reed CE, Goldberg R, Kiel K, Willett C, Sugarbaker D, Mayer R (2008) Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781. J Clin Oncol 26: 1086-1092
    • (2008) J Clin Oncol , vol.26 , pp. 1086-1092
    • Tepper, J.1    Krasna, M.J.2    Niedzwiecki, D.3    Hollis, D.4    Reed, C.E.5    Goldberg, R.6    Kiel, K.7    Willett, C.8    Sugarbaker, D.9    Mayer, R.10
  • 49
    • 0028944981 scopus 로고
    • Expression of cytokeratin-mRNAs in squamous-cell carcinoma and balloon-cell formation of human oesophageal epithelium
    • Viaene AI, Baert JH (1995) Expression of cytokeratin-mRNAs in squamous-cell carcinoma and balloon-cell formation of human oesophageal epithelium. Histochem J 27: 69-78
    • (1995) Histochem J , vol.27 , pp. 69-78
    • Viaene, A.I.1    Baert, J.H.2
  • 50
    • 1942470138 scopus 로고    scopus 로고
    • Down-regulated expression of cytokeratin 18 promotes progression of human breast cancer
    • Woelfle U, Sauter G, Santjer S, Brakenhoff R, Pantel K (2004) Down-regulated expression of cytokeratin 18 promotes progression of human breast cancer. Clin Cancer Res 10: 2670-2674
    • (2004) Clin Cancer Res , vol.10 , pp. 2670-2674
    • Woelfle, U.1    Sauter, G.2    Santjer, S.3    Brakenhoff, R.4    Pantel, K.5


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