Expression and clinical significance of P120 catenin mRNA and protein in pancreatic carcinoma

Bosnian Journal of Basic Medical Sciences

Volumn 9, Issue 3, 2009, Pages 191-197

  Fei, Yang ^a   Cheng, Zhangjun ^b   Liu, Shengli ^b   Liu, Xushun ^a   Ge, Zi ^b   Wang, Feng ^a   Zong, Guangquan ^a   Wang, Wei ^a  

^a The 81st Hospital of PLA   (China)

^b AFFILIATED ZHONGDA HOSPITAL OF SOUTHEAST UNIVERSITY   (China)

Author keywords

P120 catenin; Pancreatic carcinoma; RT PCR; Western blotting

Indexed keywords

CADHERIN ASSOCIATED SRC SUBSTRATE P120; CADHERIN-ASSOCIATED SRC SUBSTRATE P120; CELL ADHESION MOLECULE; MESSENGER RNA; PHOSPHOPROTEIN; TUMOR MARKER;

ARTICLE; FEMALE; FOLLOW UP; GENETICS; HUMAN; KAPLAN MEIER METHOD; MALE; METABOLISM; MIDDLE AGED; MORTALITY; PANCREAS TUMOR; PREDICTION AND FORECASTING; PROGNOSIS; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL ADHESION MOLECULES; FEMALE; FOLLOW-UP STUDIES; HUMANS; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; PHOSPHOPROTEINS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL;

EID: 70349933148     PISSN: 15128601     EISSN: None     Source Type: Journal    
DOI: 10.17305/bjbms.2009.2805     Document Type: Article

References (27)

1. Lowenfels A.B., Maisonneuve P. Risk factors for pancreatic cancer. J. Cell. Biochem. 2005; 95:649-656.
2. Lowenfels A.B., Maisonneuve P. Epidemiology and risk factors for pancreatic cancer. Best. Pract. Res. Clin. Gastroenterol. 2006; 20:197-209.
3. Reynolds A.B., Roesel D.J., Kanner S.B., et al. Transformation specific tyrosine phosphorylation of a novel cellular protein in chicken cells expression oncogenic variants of the avian cellular src gene. Mol. Cell. Biol. 1989; 9:629-638.
4. Kanyan X., Rebecca G.O., Christine M.C., Andrew P.K. Role of Pi2ocatenin in cadherin trafficking. Biochim. Biophys. Acta. 2007:1773:8-16.
5. Davis M.A., Ireton R.C., Reynolds A.B., A core function for p120-catenin in cadherin turnover. J. Cell. Biol. 2003; 163: 525-534.
6. Franz C.M., Ridley A.J. p120 catenin associates with microtu-bules: inverse relationship between microtubule binding and Rho GTPase regulation. J. Biol. Chem. 2004; 279:6588-6594.
7. Bellovin D.I., Bates R.C., Muzikansky A., Rimm D.L., Mercurio A.M. Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease. Cancer. Res. 2005; 65:10938-10945.
8. van Oort I.M., Tomita K., van Bokhoven A., Bussemakers M.J., et al. The prognostic value of E-cadherin and the cadherin-as-soeiated molecules alpha-, beta-, gamma-catenin and Pi2octn in prostate cancer specific survival: a long-term follow-up study. Prostate. 2007; 67:1432-1438.
9. Yvonne C., Alfred K. Y., John M. L., et al. Altered E-Cadherin expression and p120 Catenin localization in esophageal squamous cell carcinoma. Ann. Surg. Oncolo. 2007:14:3260-3267.
10. Reynolds A.B., Jenkins N.A., Gilbert D.J., et al. The gene encoding p120cas, a novel catenin, localizes on human chromosome 11q11 (CTNND) and mouse chromosome 2 (Catns). Genomics. 1996; 31:127-129.
11. Reynolds A.B. p120-catenin: Past and present. Biochim. Biophys. Acta. 2007; 1773:2-7.
12. Yanagisawa M., Anastasiadis P.Z. p120 catenin is essential for mesenchymal cadherin-mediated regulation of cell motility and invasiveness. J. Cell. Biol. 2006; 174:1087-1096.
13. Sarrio D., Perez-Mies B., Hardisson D., et al. Cytoplasmic localization of pi2octn and E-cadherin loss characterize lobular breast carcinoma from preinvasive to metastatic lesions. Oncogene. 2004; 23:3272-3283.
14. Wang EH, Liu Y, Xu HT et al. Abnormal expression and clinicopathologic significance of p120-catenin in lung cancer. Histol. Histopathol. 2006; 21:841-847.
15. Qian Z.R., Sano T., Yoshimoto K., et al. Tumor-specific downreg-ulation and methylation of the CDH13 (H-cadherin) and CDHi (E-cadherin) genes correlate with aggressiveness of human pituitary adenomas. Mod. Pathol. 2007; 20:1269-1277.
16. van Hengel J., van Roy F. Diverse functions of p120ctn in tumors. Biochim. Biophys. Acta. 2007; 1773:78-88.
17. Chartier N.T., Oddou C.I., Laine M.G., et al. Cyclin-dependent kinase 2/cyclin E complex is involved in p120 catenin (pi2octn)-dependent cell growth control: a new role for pi2octn in cancer. Cancer. Res. 2007; 67:9781-9790.
18. Miho K., Yasuka I., Yumi A. et al. p120-catenin is a novel desmog-lein 3 interacting partner: identification of the p120-catenin association site of desmoglein 3. Exp. Cell. Res. 2008:314:1683-1692.
19. Xiao K., Oas R.G., Chiasson C.M., Kowalczyk A.P. Role of p120-catenin in cadherin trafficking. Biochim. Biophys. Acta. 2007; 1773:8-16.
20. Cozzolino M., Stagni V., Spinardi L., et al. p120 Catenin Is Required for Growth Factor-dependent Cell Motility and Scattering in Epithelial Cells. Mol. Biol. Cell. 2003; 14:1964-1977.
21. Yang F., Zhang J.C., Sheng L.L., et al. Expression of P120 catenin in pancreatic carcinoma and its association with angiogenesis. Chin. J. Hepatobiliary. Surg. 2009:6:235-238.
22. Bantis A., Giannopoulos A., Gonidi M., et al. Expression of p120, Ki-67 and PCNA as proliferation biomarkers in imprint smears of prostate carcinoma and their prognostic value. Cytopathology. 2004:15:25-31.
23. Wijnhoven B.P., Pignatelli M., Dinjens W.N., Tilanus H.W. Reduced pi2octn expression correlates with poor survival in patients with adenocarcinoma of the gastroesophageal junction. J. Surg. Oncol. 2005; 92:116-123.
24. Wildenberg G A, Dohn MR, Carnahan RH et al. p 120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. Cell. 2006; 127:1027-1039.
25. Yang L., Qing C.L., Yuan M., et al. Ablation of p120-catenin enhances invasion and metastasis of human lung cancer cells Cancer. Sci. 2009; 100:441-448.
26. Davis M.A., Reynolds A.B. Blocked acinar development, E-cadherin reduction, and intraepithelial neoplasia upon ablation of p120-catenin in the mouse salivary gland. Dev. Cell. 2006; 10: 21-31.
27. Tricaud N., Perrin-Tricaud C., Bruses J.L., Rutishauer U., Adherens junction in myelinating Schwann cells stabilize Schmidt-Lanterman incisures via recruitment of p120ctn catenn to E-cadherin. J. Neurosci. 2005:25:3259-3269.