Decarboxylative grob-type fragmentations in the synthesis of trisubstituted Z olefins: Application to peloruside A, discodermolide, and EpothiloneD

Angewandte Chemie - International Edition

Volumn 48, Issue 27, 2009, Pages 5030-5033

  Prantz, Kathrin ^a   Mulzer, Johann ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

Aldol reaction; Antitumor agents; Lactones; Natural products; Quaternary stereocenters

Indexed keywords

ALDOL REACTION; ANTITUMOR AGENTS; LACTONES; NATURAL PRODUCTS; QUATERNARY STEREOCENTERS;

OLEFINS;

ALKANE; ALKENE; ANTINEOPLASTIC AGENT; CARBAMIC ACID DERIVATIVE; DESOXYEPOTHILONE B; DISCODERMOLIDE; EPOTHILONE DERIVATIVE; FUSED HETEROCYCLIC RINGS; HYDROXYL RADICAL; LACTONE; PELORUSIDE A; PYRONE DERIVATIVE;

CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

ALKANES; ALKENES; ANTINEOPLASTIC AGENTS; BICYCLO COMPOUNDS, HETEROCYCLIC; CARBAMATES; EPOTHILONES; HYDROXYL RADICAL; LACTONES; PYRONES; STEREOISOMERISM;

EID: 70349906612     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200901740     Document Type: Article

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