Poor agreement between 2 assays for measuring low levels of HIV-1 viral load

Clinical Infectious Diseases

Volumn 49, Issue 8, 2009, Pages 1283-1284

  Montaner, Julio S G ^a   Richman, Douglas D ^b   Hammer, Scott M ^c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Columbia University College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; VIRUS RNA;

DISEASE COURSE; HEALTH CARE PERSONNEL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; LETTER; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; VIRUS LOAD;

HIV INFECTIONS; HIV-1; HUMANS; STATISTICS AS TOPIC; VIRAL LOAD;

EID: 70349900446     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/605688     Document Type: Letter

References (8)

1. Hammer SM, Eron JJ, Reiss P, et al. Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA Panel. JAMA 2008;300:555-570
2. Garcia-Gasco P, Maida I, Blanco F, et al. Episodes of low-level viral rebound in HIV-infected patients on antiretroviral therapy: frequency, predictors and outcome. J Antimicrob Chemother 2008;61:699-704. (Pubitemid 351324637)
3. Petersen M, Van der Laan M, Napravnik S, Eron J, Moore R, Deeks S. Long-term consequences of the delay between virologie failure of HAART and regimen modification: a prospective cohort study [abstract K-210]. In: Program and abstracts of the 15th Conference on Retroviruses and Opportunistic Infections (Boston). 2008.
4. Gatanaga H, Tsukada K, Honda H, et al. Detection of HIV type 1 load by the Roche Cobas TaqMan assay in patients with viral loads previously undetectable by the Roche Cobas Amplicor Monitor. Clin Infect Dis 2009;48:260-262
5. Damond F, Roquebert B, Bénard A, et al. Human immunodeficiency virus type 1 (HIV-1) plasma load discrepancies between the Roche COBAS AMPLICOR HIV-1 MONITOR Version 1.5 and the Roche COBAS AmpliPrep/ COBAS TaqMan HIV-1 assays. J Clin Microbiol 2007;45:3436-3438 (Pubitemid 47585682)
6. Oliver AR, Pereira SF, Clark DA. Comparative evaluation of the automated Roche TaqMan real-time quantitative human immunodeficiency virus type 1 RNA PCR assay and the Roche AMPLICOR Version 1.5 conventional PCR assay. J Clin Microbiol 2007;45:3616-3619
7. Manavi K. The significance of low-level plasma HIV viral load on COBAS TaqMan HIV-1 assays for patients with undetectable plasma viral load on COBAS Amplicor monitor version 1.5. HIV Clin Trials 2008;9:283-286
8. Lima V, Harrigan R, Montaner JS. Increased reporting of detectable plasma HIV-1 RNA levels at the critical threshold of 50 copies per milliliter with the TaqMan assay in comparison to the Amplicor assay. J Acquir Immune Defic Syndr 2009;51:3-6.