Inhibition of endothelial cell adhesion by the new anti-inflammatory agent α-iso-cubebene

Vascular Pharmacology

Volumn 51, Issue 4, 2009, Pages 215-224

  Choi, Young Whan ^a   Kim, Hyo Jin ^b   Park, Sung Sam ^b   Chung, Jae Heun ^b   Lee, Hee Woo ^c   Oh, Sae Ock ^b   Kim, Bong Seon ^b   Kim, Jae Bong ^b   Chung, Hae Young ^a   Yu, Byung Pal ^d   Kim, Chi Dae ^b   Yoon, Sik ^b  

^a Pusan National University   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

^c Kyungpook National University School of Medicine   (South Korea)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

iso Cubebene; Antioxidant; Cell adhesion molecules; HUVEC; NF B

Indexed keywords

ALPHA ISO CUBEBENE; ALPHA TUBULIN; ANTIINFLAMMATORY AGENT; CELL ADHESION MOLECULE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NUCLEAR FACTOR KAPPA B P50; REACTIVE OXYGEN METABOLITE; SESQUITERPENE DERIVATIVE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ADHESION; CELL NUCLEUS; CELL STRAIN U937; CELL SURFACE; CONTROLLED STUDY; CYTOSOL; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; MEDICINAL PLANT; MONOCYTE; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SCHISANDRA CHINENSIS; VASCULAR DISEASE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL ADHESION; CELL SURVIVAL; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; HUMANS; INFLAMMATION MEDIATORS; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; SCHISANDRA; SESQUITERPENES; VASCULAR CELL ADHESION MOLECULE-1;

EID: 70349859764     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2009.05.008     Document Type: Article

References (45)

1. Aplin A.E., Howe A., Alahari S.K., and Juliano R.L. Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins. Pharmacol. Rev. 50 (1998) 197-263
2. Bridges A.B., Scott N.A., and Belch J.J. Probucol, a superoxide free radical scavenger in vitro. Atherosclerosis 89 (1991) 263-265
3. Chen D.F., Zhang S.X., Xie L., Xie J.X., Chen K., Kashiwada Y., Zhou B.N., Wang P., Cosentino L.M., and Lee K.H. Anti-AIDS agents-XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues. Bioorg. Med. Chem. 5 (1997) 1715-1723
4. Chen Y.G., Qin G.W., Xie Y.Y., Cheng K.F., Lin Z.W., Sun H.D., Kang Y.H., and Han B.H. Lignans from Kadsura angustifolia. J. Asian Nat. Prod. Res. 1 (1998) 125-131
5. Chen J.W., Chen Y.H., Lin F.Y., Chen Y.L., and Lin S.J. Ginkgo biloba extract inhibits tumor necrosis factor-α-induced reactive oxygen species generation, transcription factor activation, and cell adhesion molecule expression in human aortic endothelial cells. Arterioscler. Thromb. Vasc. Biol. 23 (2003) 1559-1566
6. Chen X.L., Zhang Q., Zhao R., Ding X., Tummala P.E., and Medford R.M. Rac1 and superoxide are required for the expression of cell adhesion molecules induced by tumor necrosis factor-alpha in endothelial cells. J. Pharmacol. Exp. Ther. 305 (2003) 573-580
7. Chen J.W., Lin F.Y., Chen Y.H., Wu T.C., Chen Y.L., and Lin S.J. Carvedilol inhibits tumor necrosis factor-alpha-induced endothelial transcription factor activation, adhesion molecule expression, and adhesiveness to human mononuclear cells. Arterioscler. Thromb. Vasc. Biol. 24 (2004) 2075-2081
8. Chiu P.Y., Mak D.H., Poon M.K., and Ko K.M. In vivo antioxidant action of a lignan-enriched extract of Schisandra fruit and an anthraquinone-containing extract of Polygonum root in comparison with schisandrin B and emodin. Planta Med. 68 (2002) 951-956
9. Choi Y.W., Takamatsu S., Khan S.I., Srinivas P.V., Ferreira D., Zhao J., and Khan I.A. Schisandrene, a dibenzocyclooctadiene lignan from Schisandra chinensis: structure-antioxidant activity relationships of dibenzocyclooctadiene lignans. J. Nat. Prod. 69 (2006) 356-359
10. Cianchetti S., Del Fiorentino A., Colognato R., Di Stefano R., Franzoni F., and Pedrinelli R. Anti-inflammatory and anti-oxidant properties of telmisartan in cultured human umbilical vein endothelial cells. Atherosclerosis 198 (2008) 22-28
11. Collins T. Endothelial nuclear factor-kappa B and the initiation of the atherosclerotic lesion. Lab. Invest. 68 (1993) 499-508
12. Cominacini L., Garbin U., Pasini A.F., Davoli A., Campagnola M., Contessi G.B., Pastorino A.M., and Lo C.V. Antioxidants inhibit the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 induced by oxidized LDL on human umbilical vein endothelial cells. Free Radic. Biol. Med. 22 (1997) 117-127
13. Cybulsky M.I., and Gimbrone Jr. M.A. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science 251 (1991) 788-791
14. Fruebis J., Gonzalez V., Silvestre M., and Palinski W. Effect of probucol treatment on gene expression of VCAM-1, MCP-1, and M-CSF in the aortic wall of LDL receptor-deficient rabbits during early atherogenesis. Arterioscler. Thromb. Vasc. Biol. 17 (1997) 1289-1302
15. Gille J., Paxton L.L., Lawley T.J., Caughman S.W., and Swerlick R.A. Retinoic acid inhibits the regulated expression of vascular cell adhesion molecule-1 by cultured dermal microvascular endothelial cells. J. Clin. Invest. 99 (1997) 492-500
16. Griendling K.K., Sorescu D., Lassegue B., and Ushio-Fukai M. Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler. Thromb. Vasc. Biol. 20 (2000) 2175-2183
17. Harrison D., Griendling K.K., Landmesser U., Hornig B., and Drexler H. Role of oxidative stress in atherosclerosis. Am. J. Cardiol. 91 3A (2003) 7-11
18. Iiyama K., Hajra L., Iiyama M., Li H., DiChiara M., Medoff B.D., and Cybulsky M.I. Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation. Circ. Res. 85 (1999) 199-207
19. Inoue K., Kobayashi M., Yano K., Miura M., Izumi A., Mataki C., Doi T., Hamakubo T., Reid P.C., Hume D.A., Yoshida M., Aird W.C., Kodama T., and Minami T. Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression. Arterioscler. Thromb. Vasc. Biol. 26 (2006) 2652-2659
20. Kunsch C., Luchoomun J., Grey J.Y., Olliff L.K., Saint L.B., Arrendale R.F., Wasserman M.A., Saxena U., and Medford R.M. Selective inhibition of endothelial and monocyte redox-sensitive genes by AGI-1067: a novel antioxidant and anti-inflammatory agent. J. Pharmacol. Exp. Ther. 308 (2004) 820-829
21. Kunsch C., and Medford R.M. Oxidative stress as a regulator of gene expression in the vasculature. Circ. Res. 85 (1999) 753-766
22. Kuo Y.H., Kuo L.M., and Chen C.F. Four new C19 homolignans, schiarisanrins A, B, and D and cytotoxic schiarisanrin C, from Schizandra arisanensis. J. Org. Chem. 62 (1997) 6242-6245
23. Lee, Y.J., Shim, J.W., Lee, Y.J., Park, Y.H., Lee, H.Y., Kim, S.D., Choi, Y.W., Bae, Y.S., 2009. Identification of a novel compound that stimulates intracellular calcium increase and CXCL8 production in human neutrophils from Schisandra chinensis. Biochem. Biophys. Res. Commun. 379 (4), 928-932.
24. Li H., Cybulsky M.I., Gimbrone Jr. M.A., and Libby P. An atherogenic diet rapidly induces VCAM-1, a cytokine regulatable adhesion mononuclear leukocyte adhesion molecule, in rabbit aortic endothelium. Arterioscler. Thromb. 14 (1993) 197-204
25. Lin C.P., Lin W.T., Leu H.B., Wu T.C., and Chen J.W. Differential mononuclear cell activity and endothelial inflammation in coronary artery disease and cardiac syndrome X. Int. J. Cardiol. 89 (2003) 53-62
26. Lusis A.J. Atherosclerosis. Nature 407 (2000) 233-241
27. Manna S.K., Zhang H.J., Yan T., Oberley L.W., and Aggarwal B.B. Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappa B and activated protein-1. J. Biol. Chem. 273 (1998) 13245-13254
28. Martin T., Cardarelli P.M., Parry G.C., Felts K.A., and Cobb R.R. Cytokine induction of monocyte chemoattractant protein-1 gene expression in human endothelial cells depends on the cooperative action of NF-kappa B and AP-1. Eur. J. Immunol. 27 (1997) 1091-1097
29. Marui N., Offermann M.K., Swerlick R., Kunsch C., Rosen C.A., Ahmad M., Alexander R.W., and Medford R.M. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant sensitive mechanism in human vascular endothelial cells. J. Clin. Invest. 92 (1993) 1866-1874
30. Muller J.M., Rupec R.A., and Baeuerle P.A. Study of gene regulation by NF-κB and AP-1 in response to reactive oxygen intermediates. Methods 11 (1997) 301-312
31. Nizamutdinova I.T., Jung J.J., Choi J.Y., Lee S.H., Kang S.S., Kim Y.S., Chang K.C., and Kim H.J. Hesperidin, hesperidine methyl chalone and phellopterin from Poncirus trifoliate (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-a-stimulated human umbilical vein endothelial cells. Int. Immunopharmacol. 8 (2008) 670-678
32. Offermann M.K., and Medford R.M. Antioxidants and atherosclerosis: a molecular perspective. Heart Dis. Stroke 3 (1994) 52-57
33. Rhyu M.R., Kim E.Y., Yoon B.K., Lee Y.J., and Chen S.N. Aqueous extract of Schizandra chinensis fruit causes endothelium-dependent and -independent relaxation of isolated rat thoracic aorta. Phytomedicine 13 (2006) 651-657
34. Ross R. Cell biology of atherosclerosis. Annu. Rev. Physiol. 57 (1995) 791-804
35. Ross R. Atherosclerosis: an inflammatory disease. N. Engl. J. Med. 340 (1999) 115-126
36. Springer T.A. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76 (1994) 301-314
37. Tardif J.C., Gregoire J., and L'Allier P.L. Prevention of restenosis with antioxidants: mechanisms and implications. Am. J. Cardiovasc. Drugs 2 (2002) 323-334
38. Wang C., Mäkelä T., Hase T., Adlercreutz H., and Kurzer M.S. Lignans and flavonoids inhibit aromatase enzyme in human preadipocytes. J. Steroid Biochem. Mol. Biol. 50 (1994) 205-212
39. Weber C., Erl W., Pietsch A., Strobel M., Ziegler-Heitbrock H.W., and Weber P.C. Antioxidants inhibit monocyte adhesion by suppressing nuclear factor-kappa B mobilization and induction of vascular cell adhesion molecule-1 in endothelial cells stimulated to generate radicals. Arterioscler. Thromb. 14 (1994) 1665-1673
40. Weber C., Erl W., Pietsch A., and Weber P.C. Aspirin inhibits nuclear factor-κB mobilization and monocyte adhesion in stimulated human endothelial cells. Circulation 91 (1995) 1914-1917
41. Wolle J., Hill R.R., Ferguson E., Devall L.J., Trivedi B.K., Newton R.S., and Saxena U. Selective inhibition of tumor necrosis factor-induced vascular cell adhesion molecule-1 gene expression by a novel flavonoid. Lack of effect on transcription factor NF-kappa B. Arterioscler. Thromb. Vasc. Biol. 16 (1996) 1501-1508
42. Wu M.D., Huang R.L., Kuo L.M., Hung C.C., Ong C.W., and Kuo Y.H. The anti-HBsAg (human type B hepatitis, surface antigen) and anti-HBeAg (human type B hepatitis, e antigen) C18 dibenzocyclooctadiene lignans from Kadsura matsudai and Schizandra arisanensis. Chem. Pharm. Bull. (Tokyo) 51 (2003) 1233-1236
43. Yasukawa K., Ikeya Y., Mitsuhashi H., Iwasaki M., Aburada M., Nakagawa S., Takeuchi M., and Takido M. Gomisin A inhibits tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin. Oncology 49 (1992) 68-71
44. Zapolska-Downar D., Zapolski-Downar A., Markiewski M., Ciechanowicz A., Kaczmarczyk M., and Naruszewicz M. Selective inhibition by probucol of vascular cell adhesion molecule-1 (VCAM-1) expression in human vascular endothelial cells. Atherosclerosis 155 (2001) 123-130
45. Zhu Y., Lin J.H., Liao H.L., Friedli Jr. O., Verna L., Marten N.W., Straus D.S., and Stemerman M.B. LDL induces transcription factor activator protein-1 in human endothelial cells. Arterioscler. Thromb. Vasc. Biol. 18 (1998) 473-480