Pancreatic cancerrelated cachexia: Influence on metabolism and correlation to weight loss and pulmonary function

BMC Cancer

Volumn 9, Issue , 2009, Pages 255-

  Bachmann, Jeannine ^a   Ketterer, Knut ^a   Marsch, Christiane ^b   Fechtner, Kerstin ^b   Krakowski Roosen, Holger ^c   Büchler, Markus W ^b   Friess, Helmut ^a   Martignoni, Marc E ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE TISSUE; ADULT; AGED; ARTICLE; CACHEXIA; CANCER GROWTH; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; HUMAN; LUNG DISEASE; MAJOR CLINICAL STUDY; MALE; METASTASIS; MUSCLE TISSUE; NUTRITIONAL STATUS; PANCREAS ADENOCARCINOMA; PANCREAS RESECTION; WEIGHT REDUCTION; CANCER STAGING; LUNG; METABOLISM; MIDDLE AGED; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; PATHOPHYSIOLOGY;

AGED; CACHEXIA; CARCINOMA, PANCREATIC DUCTAL; FEMALE; HUMANS; LUNG; MALE; MIDDLE AGED; NEOPLASM STAGING; PANCREATIC NEOPLASMS;

EID: 70349847241     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-9-255     Document Type: Article

References (37)

1. Carpelan-Holmstrom M, Nordling S, Pukkala E, Sankila R, Luttges J, Kloppel G, Haglund C. Does anyone survive pancreatic ductal adenocarcinoma? A nationwide study re-evaluating the data of the Finnish Cancer Registry. Gut 2005, 54:385-387. 1774412, 15710987, 10.1136/gut.2004.047191.
2. Friess H, Isenmann R, Berberat P, Kleeff J, Buchler MW. [Prognosis in pancreatic carcinoma]. Ther Umsch 1996, 53(5):401-407.
3. Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, Feuer EJ, Thun MJ. Cancer statistics. CA Cancer J Clin 2005, 55:10-30. 10.3322/canjclin.55.1.10, 15661684.
4. Beger HG, Rau B, Gansauge F, Poch B, Link KH. Treatment of pancreatic cancer: challenge of the facts. World J Surg 2003, 27:1075-1084. 10.1007/s00268-003-7165-7, 12925907.
5. Conlon KC, Klimstra DS, Brennan MF. Long-term survival after curative resection for pancreatic ductal adenocarcinoma. Clinicopathologic analysis of 5-year survivors. Ann Surg 1996, 223:273-279. 1235115, 8604907, 10.1097/00000658-199603000-00007.
6. Cooperman AM. Pancreatic cancer: the bigger picture. Surg Clin North Am 2001, 81:557-574. 10.1016/S0039-6109(05)70143-2, 11459271.
7. Imamura M, Doi R, Imaizumi T, Funakoshi A, Wakasugi H, Sunamura M, Ogata Y, Hishinuma S, Asano T, Aikou T, Hosotani R, Maetani S. A randomized multicenter trial comparing resection and radiochemotherapy for resectable locally invasive pancreatic cancer. Surgery 2004, 136:1003-1011. 10.1016/j.surg.2004.04.030, 15523393.
8. Kleeff J, Michalski C, Friess H, Buchler MW. Pancreatic cancer: from bench to 5-year survival. Pancreas 2006, 33:111-118. 10.1097/01.mpa.0000229010.62538.f2, 16868475.
9. Kleeff J, Michalski CW, Friess H, Buchler MW. Surgical treatment of pancreatic cancer: The role of adjuvant and multimodal therapies. Eur J Surg Oncol 2007, 33:817-823.
10. Wagner M, Redaelli C, Lietz M, Seiler CA, Friess H, Buchler MW. Curative resection is the single most important factor determining outcome in patients with pancreatic adenocarcinoma. Br J Surg 2004, 91:586-594. 10.1002/bjs.4484, 15122610.
11. Freelove R, Walling AD. Pancreatic cancer: diagnosis and management. American family physician 2006, 73:485-492.
12. Dank M. [Tumorus anorexia/cachexia syndrome]. Magy Onkol 2001, 45:431-436.
13. DiMagno EP. Pancreatic cancer: clinical presentation, pitfalls and early clues. Ann Oncol 1999, 10:140-142. 10.1023/A:1008382029375, 10436807.
14. Ockenga J, Pirlich M, Gastell S, Lochs H. Tumour anorexia-tumour cachexia in case of gastrointestinal tumours: standards and visions. Zeitschrift fur Gastroenterologie 2002, 40:929-936. 10.1055/s-2002-35411, 12436371.
15. Deans C, Wigmore SJ. Systemic inflammation, cachexia and prognosis in patients with cancer. Curr Opin Clin Nutr Metab Care 2005, 8:265-269.
16. Davidson W, Ash S, Capra S, Bauer J, . Cancer Cachexia Study Group Weight stabilisation is associated with improved survival duration and quality of life in unresectable pancreatic cancer. Clin Nutr 2004, 23:239-247. 10.1016/j.clnu.2003.07.001, 15030964.
17. Costelli P, Baccino FM. Mechanisms of skeletal muscle depletion in wasting syndromes: role of ATP-ubiquitin-dependent proteolysis. Curr Opin Clin Nutr Metab Care 2003, 6:407-412. 10.1097/00075197-200307000-00009, 12806214.
18. Falconer JS, Fearon KC, Ross JA, Elton R, Wigmore SJ, Garden OJ, Carter DC. Acute-phase protein response and survival duration of patients with pancreatic cancer. Cancer 1995, 75:2077-2082. 10.1002/1097-0142(19950415)75:8<2077::AID-CNCR2820750808>3.0.CO;2-9, 7535184.
19. Fearon KC, Barber MD, Falconer JS, McMillan DC, Ross JA, Preston T. Pancreatic cancer as a model: inflammatory mediators, acute-phase response, and cancer cachexia. World J Surg 1999, 23:584-588. 10.1007/PL00012351, 10227928.
20. Tisdale MJ. Cancer cachexia. Langenbecks Arch Surg 2004, 389:299-305. 10.1007/s00423-004-0486-7, 15168125.
21. Bosaeus I, Daneryd P, Svanberg E, Lundholm K. Dietary intake and resting energy expenditure in relation to weight loss in unselected cancer patients. Int J Cancer 2001, 93:380-383. 10.1002/ijc.1332, 11433403.
22. Camps C, Iranzo V, Bremnes RM, Sirera R. Anorexia-Cachexia syndrome in cancer: implications of the ubiquitin-proteasome pathway. Support Care Cancer 2006, 14:1173-1183. 10.1007/s00520-006-0097-7, 16819628.
23. Agustsson T, Ryden M, Hoffstedt J, van Harmelen V, Dicker A, Laurencikiene J, Isaksson B, Permert J, Arner P. Mechanism of increased lipolysis in cancer cachexia. Cancer Res 2007, 67:5531-5537. 10.1158/0008-5472.CAN-06-4585, 17545636.
24. Inui A. Cancer anorexia-cachexia syndrome: are neuropeptides the key?. Cancer Res. 1999, 59(18):4493-4501.
25. Laviano A, Meguid MM, Inui A, Muscaritoli M, Rossi-Fanelli F. Therapy insight: Cancer anorexia-cachexia syndrome-when all you can eat is yourself. Nat Clin Pract Oncol 2005, 2:158-165. 10.1038/ncponc0112, 16264909.
26. Nelson KA. Modern management of the cancer anorexia-cachexia syndrome. Curr Oncol Rep 2000, 2:362-368. 10.1007/s11912-000-0031-y, 11122866.
27. Ripamonti C. Management of dyspnea in advanced cancer patients. Support Care Cancer. 1999, 7(4):233-243. 10.1007/s005200050255, 10423049.
28. Ripamonti C, Fusco F. Respiratory problems in advanced cancer. Supportive care in cancer: Official journal of the Multinational Association of Supportive. Support Care Cancer. 2002, 10(3):204-216. 10.1007/s005200100296, 11904785.
29. Kispert JF, Kazmers A, Roitman L. Preoperative spirometry predicts perioperative pulmonary complications after major vascular surgery. Am Surg 1992, 58:491-495.
30. Sobin LH, Wittekind C. Pancreas. UICC/TNM classification of malignant tumors 1997, 87-90. Heidelberg Springer Medizin, Sobin LH, Wittekind C.
31. Wittekind C, Meyer HJ, Bootz F. Pankreas. TNM Klassifikation maligner Tumoren 2006, 83-85.
32. Buchler MW, Friess H, Wagner M, Kulli C, Wagener V, Z'Graggen K. Pancreatic fistula after pancreatic head resection. Br J Surg 2000, 87:883-889. 10.1046/j.1365-2168.2000.01465.x, 10931023.
33. Friess H, Beger HG, Sulkowski U, Becker H, Hofbauer B, Dennler HJ, Buchler MW. Randomized controlled multicentre study of the prevention of complications by octreotide in patients undergoing surgery for chronic pancreatitis. Br J Surg 1995, 82:1270-1273. 10.1002/bjs.1800820938, 7552016.
34. Ferrone CR, Finkelstein DM, Thayer SP, Muzikansky A, Fernandez-delCastillo C, Warshaw AL. Perioperative CA19-9 levels can predict stage and survival in patients with resectable pancreatic adenocarcinoma. J Clin Oncol 2006, 24:2897-2902. 10.1200/JCO.2005.05.3934, 16782929.
35. Ortiz-Gonzalez J, Alvarez-Aguila NP, Medina-Castro JM. Adjusted carbohydrate antigen 19-9. Correlation with histological grade in pancreatic adenocarcinoma. Anticancer Res 2005, 25:3625-3627.
36. Rai A, Tewari M, Mohapatra SC, Shukla HS. Correlation of nutritional parameters of gallbladder cancer patients. J Surg Oncol 2006, 93:705-708. 10.1002/jso.20539, 16724358.
37. Buchler MW, Wagner M, Schmied BM, Uhl W, Friess H, Z'graggen K. Changes in morbidity after pancreatic resection: toward the end of completion pancreatectomy. Arch Surg 2003, 138:1310-1314. 10.1001/archsurg.138.12.1310, 14662530.