Simultaneous separation and determination of lamivudine and zidovudine in pharmaceutical formulations using the HPTLC method

Analytical Letters

Volumn 42, Issue 11, 2009, Pages 1552-1570

  Habte, Girum ^a   Hymete, Ariaya ^a   Mohamed, Abdel Maaboud Ismail ^a  

^a ADDIS ABABA UNIVERSITY   (Ethiopia)

Author keywords

Densitometric detection; HPTLC; Lamivudine and zidovudine combinations; Simultaneous determination

Indexed keywords

EID: 70349839178     PISSN: 00032719     EISSN: 1532236X     Source Type: Journal    
DOI: 10.1080/00032710902993852     Document Type: Article

References (14)

1. AIDSinfo. 2007. Lamivudine/Sidovudine. Available at http://www.aidsinfo.nih.gov/DrugsNew/DrugDetailT.aspx?MenuItem=Drugs&int_id=285&Search=Off&ClassID=&TypeID=#FA1.
2. AVERT. 2007. Introduction to HIV=AIDS Treatment. Available at http://www.avert.org/introtrt.htm
3. Bahrami, G., S. Mirzaeei, A. Kiani, and B. Mohammadi. 2005. High-performance liquid chromatographic determination of lamivudine in human serum using liquid-liquid extraction: Application to pharmacokinetic studies. J. Chromatogr. B 823: 213-217.
4. Dunge, A., N. Sharda, B. Singh, and S. Singh. 2005. Validated specific HPLC method for determination of zidovudine during stability studies. J. Pharm. Biomed. Anal. 37: 1109-1114.
5. Kazue, K. E., D. C. Helena, M. E. Emiko, A. S. Schramm, and V. Porta. 2005. Determination of lamivudine in human plasma by HPLC and its use in bioequivalence studies. Int. J. Pharm. 297: 73-79.
6. ICH. 1994. Text on Validation of Analytical Procedures. Available at http://urlwww.biologicsconsulting.com/docs/ich/ICHQ2A.pdf
7. ICH. 1996. Validation of Analytical procedures: Methodology. Available at http://www.biologicsconsulting.com/docs/ich/ICHQ2B.pdf
8. Kaul, N., S. R. Dhaneshwar, H. Agrawal, A. Kakad, and B. Patil. 2004. Application of HPLC and HPTLC for the simultaneous determination of tizanidine and rofecoxib in pharmaceutical dosage form. J. Pharm. Biomed. Anal. 37: 27-38.
9. Kenney, K. B., S. A. Wring, R. M. Carr, G. N. Wells, and J. Dunn. 2000. Simultaneous determination of zidovudine and lamivudine in human serum using HPLC with tandem mass spectrometry. Pharm. Biomed. Anal. 22: 967-983.
10. Pereira, A. S., K. B. Kenney, M. S. Cohen, J. E. Hall, and J. J. Eron. 2000. Simultaneous determination of lamivudine and zidovudine concentrations in human seminal plasma using high-performance liquid chromatography and tandem mass spectrometry. J. Chromatogr. B 742: 173-183.
11. Pharmainfo.net. 2006. Methods of Estimation of Multi-component Formulations: A Review. Available at http://www.pharmainfo.net/exclusive/reviews/methods_of_estimation_of_multi-component_formulations:_a_review/
12. Richman, D. D. 2006. Antiviral drug resistance. Antiviral Res. 71: 117-121.
13. Saliba, G., and P. Yeni. 2006. Recent and future therapeutic advances in the management of HIV infection. Pathologie Biologie 54: 545-550.
14. Uslu, B., and S. A. Ozkan. 2002. Determination of lamivudine and zidovudine in binary mixtures using first derivative spectrophotometric, first derivative of the ratio spectra and high-performance liquid chromatography-UV methods. Anal. Chim. Acta 466: 175-185.