Simplified kinetic calibration of solid-phase microextraction for in vivo pharmacokinetics

Journal of Chromatography A

Volumn 1216, Issue 45, 2009, Pages 7664-7669

  Zhang, Xu ^a,b   Es haghi, Ali ^c   Cai, Jibao ^a,b   Pawliszyn, Janusz ^b  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b UNIVERSITY OF WATERLOO   (Canada)

^c RAZI VACCINE AND SERUM RESEARCH INSTITUTE   (Iran)

Author keywords

In vivo SPME; Pharmacokinetics; Single point kinetic calibration

Indexed keywords

ANALYTE CONCENTRATION; CALIBRATION METHOD; DESORPTION KINETICS; DYNAMIC MONITORING; HIGH-THROUGHPUT ANALYSIS; IN VIVO SPME; IN-VITRO; IN-VIVO; KINETIC CALIBRATION; OPTIMAL TIME; PHARMACOKINETIC STUDIES; POINT KINETICS; SAMPLING TIME; SINGLE-POINT KINETIC CALIBRATION; SOLID-PHASE MICROEXTRACTION; THEORETICAL FOUNDATIONS;

DESORPTION; DEUTERIUM; EXTRACTION; PHARMACOKINETICS; STANDARDS;

CALIBRATION;

DIAZEPAM; NORDAZEPAM; OXAZEPAM;

ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; CONTROLLED STUDY; DESORPTION; DOG; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DETERMINATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SOLID PHASE MICROEXTRACTION; VALIDATION PROCESS;

ADSORPTION; ANIMALS; BENZODIAZEPINONES; CALIBRATION; DOGS; KINETICS; POLYETHYLENE GLYCOLS; SOLID PHASE MICROEXTRACTION;

EID: 70349816656     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.09.021     Document Type: Article

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