Conserved leucine residue in the head region of morbillivirus fusion protein regulates the large conformational change during fusion activity

Biochemistry

Volumn 48, Issue 38, 2009, Pages 9112-9121

  Plattet, Philippe ^a   Langedijk, Johannes P M ^b   Zipperle, Ljerka ^a   Vandevelde, Marc ^a   Örvell, Claes ^c   Zurbriggen, Andreas ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b Pepscan Systems   (Netherlands)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CANINE DISTEMPER VIRUS; CELL SURFACE RECEPTORS; CELL SURFACES; CELL-CELL FUSION; CLASS I; CO-IMMUNOPRECIPITATION ASSAYS; COILED COIL; CONFORMATIONAL CHANGE; CONFORMATIONAL SWITCHES; ENVELOPE GLYCOPROTEINS; FUSION ACTIVITY; FUSION PROTEINS; HEPTAD REPEAT REGIONS; LEUCINE RESIDUES; LOW TEMPERATURES; PLASMA MEMBRANES; RECEPTOR BINDING; STRUCTURAL DIFFERENCES;

AMINO ACIDS; MONOCLONAL ANTIBODIES; PROTEINS; SURFACE DEFECTS;

CELL MEMBRANES;

LEUCINE; MONOCLONAL ANTIBODY; PARAMYXOVIRUS F PROTEIN; PARAMYXOVIRUS H PROTEIN; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS FUSION PROTEIN; EPITOPE; F PROTEIN, PHOCINE DISTEMPER VIRUS; RECOMBINANT PROTEIN; VIRUS ANTIGEN; VIRUS PROTEIN;

ARTICLE; CANINE DISTEMPER MORBILLIVIRUS; CELL FUSION; CONTROLLED STUDY; GENE MUTATION; LOW TEMPERATURE PROCEDURES; MEASLES VIRUS; NONHUMAN; PARAMYXOVIRUS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; RECEPTOR BINDING; VERO CELL; VIRUS ENTRY; VIRUS MORPHOLOGY; AMINO ACID SUBSTITUTION; ANIMAL; CERCOPITHECUS; CHEMICAL STRUCTURE; CHEMISTRY; DOG; GENETICS; IMMUNOLOGY; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS; TEMPERATURE; THERMODYNAMICS;

CANINE DISTEMPER VIRUS; MORBILLIVIRUS; PARAMYXOVIRIDAE;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, VIRAL; CERCOPITHECUS AETHIOPS; CONSERVED SEQUENCE; DISTEMPER VIRUS, CANINE; DOGS; EPITOPES; LEUCINE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN FOLDING; RECOMBINANT PROTEINS; TEMPERATURE; THERMODYNAMICS; VERO CELLS; VIRAL FUSION PROTEINS; VIRAL PROTEINS; VIRUS INTERNALIZATION;

EID: 70349784080     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9008566     Document Type: Article

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