Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins

Neurobiology of Disease

Volumn 36, Issue 2, 2009, Pages 320-330

  Yang, Lichuan ^a   Shi, Qingli ^b   Ho, Daniel J ^a   Starkov, Anatoly A ^a   Wille, Elizabeth J ^a   Xu, Hui ^b   Chen, H L ^b   Zhang, Steven ^a   Stack, Cliona M ^a   Calingasan, Noel Y ^a   Gibson, Gary E ^b   Beal, M Flint ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b BURKE MEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

ketoglutarate dehydrogenase complex; Huntington; Mitochondria; Neurodegenerative diseases; Oxidative damage; Parkinson

Indexed keywords

DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE; DNA; DOPAMINE; MESSENGER RNA; MITOCHONDRIAL ENZYME; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DEGENERATIVE DISEASE; EMBRYO; FEMALE; LIPID PEROXIDATION; MALE; MOUSE; NEUROTOXICITY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SUBSTANTIA NIGRA; WILD TYPE;

ANIMALS; BRAIN; COENZYME A-TRANSFERASES; ENERGY METABOLISM; ENZYME ACTIVATION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; ISOENZYMES; KETOGLUTARATE DEHYDROGENASE COMPLEX; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; NEURODEGENERATIVE DISEASES; NEUROTOXINS;

EID: 70349777278     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2009.07.023     Document Type: Article

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