In vitro percutaneous absorption of benzene in human

Cutaneous and Ocular Toxicology

Volumn 28, Issue 2, 2009, Pages 65-70

  Hui, Xiaoying ^a   Wester, Ronald C ^a   Barbadillo, Sherry ^a   Cashmore, Anne ^a   Maibach, Howard I ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Benzene; EPA guidelines; Human skin; Percutaneous absorption

Indexed keywords

BENZENE; CARBON 14; DOMESTIC CHEMICAL; VOLATILE AGENT; CARBON; DETERGENT;

ARTICLE; CADAVER; CLEANING; DERMATOME; DIFFUSION; ENVIRONMENTAL PROTECTION; EVAPORATION; EXPOSURE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; ISOTOPE LABELING; RADIOACTIVITY; SKIN ABSORPTION; WORKPLACE; CHEMISTRY; DRUG EFFECT; METABOLISM; OCCUPATIONAL EXPOSURE; SKIN; TOPICAL DRUG ADMINISTRATION; VOLATILIZATION;

ADMINISTRATION, TOPICAL; BENZENE; CARBON RADIOISOTOPES; DETERGENTS; HUMANS; OCCUPATIONAL EXPOSURE; SKIN; SKIN ABSORPTION; VOLATILIZATION;

EID: 70349776477     PISSN: 15569527     EISSN: 15569535     Source Type: Journal    
DOI: 10.1080/15569520902826609     Document Type: Article

References (14)

1. International Agency for Research on Cancer. Summaries & Evaluations. Benzene. Volume 29 (1982); Supplement 7. Lyon, France: IARC. 1987.
2. Schnalter AR, Rosamilia K, Wojcik NC. Review of the literature on benzene exposure and leukemia subtypes. Chem Biol Interact. 2005; 153-154:9-21.
3. Capleton AC, Levy LS. An overview of occupational benzene exposures and occupational exposure limits in Europe and North America. Chem Biol Interact. 2005; 153-154:43-53.
4. Wester RC, Maibach HI, Gruenke LD, Caig JC. Benzene levels in ambient air and breath of smokers and nonsmokers in urban and pristine environments. J Toxicol Environ Health. 1986; 18:567-573.
5. Maibach HI, Anjo DM. Percutaneous penetration of benzene and benzene contained in solvents used in the rubber industry. Arch Environ Health. 1981; 36:256-260.
6. Environmental Protection Agency. EPA Guidelines: EPA Test Rule File: In Vitro Dermal Absorption Rate Testing of Certain Chemicals of Interest to the Occupational Safety and Health Administration. Fed Regist Apr 26, 2004; 69(80):22402-22441.
7. Wester RC, Christoffel J, Hartway T, Poblete N, Maibach HI, Forsell J. Human cadaver skin viability for in vitro percutaneous absorption: storage and detrimental effects of heat-separation and freezing. Pharm Res. 1998; 15:82-84.
8. Messager S, Hann AC, Goddard PA, Dettmar PW, Maillard JY. Assessment of skin viability: is it necessary to use different methodologies? Skin Res Technol. 2003; 9(4):321-330.
9. Collier SW, Sheikh NM, Sakr A, Lichtin JL, Stewart RF, Bronaugh RL. Maintenance of skin viability during in vitro percutaneous absorption/metabolism studies. Toxicol Appl Pharmacol. 1989; 99(3):522-533.
10. Wester R, Mobayen M, Maibach HI. In vivo and in vitro absorption and binding to powdered stratum corneum as methods to evaluate skin absorption of environmental chemical contaminants from ground and surface water. J Toxicol Environ Health. 1987; 21:367-1324
11. Feldmann RJ, Maibach HI. Systemic Absorption of Pesticides Through the Skin of Man. Appendix B. Occupational Exposure to Pesticides; Federal Working Group on Pest Management; Washington, DC. 1974:120-128.
12. Zhai H, Maibach HI. Effects of skin occlusion on percutaneous absorption: an overview. Skin Pharmacol Appl Skin Physiol. 2001; 14:1-10. (Pubitemid 32098521)
13. Wester RC, Maibach HI. Percutaneous absorption: short-term exposure, lag time, multiple exposures, model variations, and absorption from clothing. In: Vos JG, Younes M, Smith E, eds. Allergic Hypersensitivities Induced by Chemicals; Boca Raton, FL: CRC Press. 1996:35-48.
14. Wester RC, Maibach HI. Benzene percutaneous absorption: dermal exposure relative to other benzene sources. Int J Occup Environ Health. 2000; 6(2):122-126.