Efficacy of six-dose regimen of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria, three years after its introduction into Ethiopia

Parasite

Volumn 16, Issue 2, 2009, Pages 129-134

  Kefyalew, T ^a   Animut, A ^a   Tamene, T ^a   Jima, D ^b   Hailemariam, A ^b   Legesse, M ^a  

^a ADDIS ABABA UNIVERSITY   (Ethiopia)

^b Federal Ministry of Health   (Ethiopia)

Author keywords

Artemether lumefantrine; Efficacy; Ethiopia; Malaria; P. Falciparum

Indexed keywords

PLASMODIUM FALCIPARUM;

ANTIMALARIAL AGENT; ARTEMETHER LUMEFANTRINE COMBINATION; ARTEMETHER-LUMEFANTRINE COMBINATION; ARTEMISININ DERIVATIVE; ETHANOLAMINE DERIVATIVE; FLUORENE DERIVATIVE;

ADOLESCENT; ADULT; ARTICLE; CHILD; DRUG COMBINATION; ETHIOPIA; FEMALE; HUMAN; INFANT; MALARIA FALCIPARUM; MALE; MIDDLE AGED; PLASMODIUM VIVAX MALARIA; PRESCHOOL CHILD; TREATMENT OUTCOME;

ADOLESCENT; ADULT; ANTIMALARIALS; ARTEMISININS; CHILD; CHILD, PRESCHOOL; DRUG COMBINATIONS; ETHANOLAMINES; ETHIOPIA; FEMALE; FLUORENES; HUMANS; INFANT; MALARIA, FALCIPARUM; MALARIA, VIVAX; MALE; MIDDLE AGED; TREATMENT OUTCOME; YOUNG ADULT;

EID: 70349772773     PISSN: 1252607X     EISSN: None     Source Type: Journal    
DOI: 10.1051/parasite/2009162129     Document Type: Article

References (27)

1. ADAMA T., LEON R., VINCENT R., AHMED B.S., FREDERIC A. & MILIJAONA R. Efficacy of artesunate plus amodiaquine, artesunate plus sulfadoxine- pyrimethamine, and chloroquine plus sulfadoxine-pyrimethamine in patients with uncomplicated Plasmodium falciparum in the Comoros Union. Acta Tropica, 2007, 102, 176-181.
2. BAKSHI R., HERMELING-FRITZ I., GATHMANN I. & ALTERI E. An integrated assessment of the clinical safety of artemether-lumefantrine: a new oral fixed-dose combination antimalarial drug. Transaction of the Royal Society of Tropical Medicine and Hygiene, 2000, 94, 419-924.
3. FALADE C, MAKANGA M., PREMJI Z., ORTMANN C.E., STOCKMEYER M. & DE PALACIOS P.I. Efficacy and safety of artemether-lumefantrine (Coartem®) tablets (six-dose regimen) in African infants and children with, acute, uncomplicated falciparum malaria. Transaction of the Royal Society of Tropical Medicine and Hygiene, 2005, 99, 459-467.
4. FAYE B., NDIAYE J.L., NDIAYE D., DIENG Y,, FAYE O. & GAYE O. Efficacy and tolerability of four antimalarial combinations in the treatment of uncomplicated Plasmodium falciparum malaria in Senegal. Malaria Journal, 2007, 6, 80-89.
5. nd edition. Addis Ababa, Ethiopia, 2004.
6. GUTHMANN J.P., COHUET S., RIGUTTO C, FORTES F., SARAIVA N., KIGULI J., KYOMUHENDO J., FRANCIS M., NOEL F., MULEMBA M. & BALKAN S. High efficacy of two artemisinin-based combinations (artesunate + amodiaquine and artemether + lumefantrine) in Caala, Central Angola, American Journal of Tropical Medicine and Hygiene, 2006, 75, 143-145.
7. HASTINGS I.M., KORENROMP E.L. & BLOLAND P.B. The anatomy of a malaria disaster: drug policy choice and mortality in African children. Lancet Infectious Diseases, 2007, 7, 739-748.
8. HATZ C., SOTO J., NOTHDURFT H.D., ZOLLER T., WEITZEL T., LOUTAN L,, BRICAIRE F., GAY F., BURCHARD G.D., ANDRIANO K., LEFEVRE G., DE PALACIOS P.I, & GENTON B. Treatment, of acute uncomplicated falciparum malaria with artemether-lumefantrine in nonimmune populations: a safety, efficacy, and pharmacokinetic study. American Journal of Tropical Medicine and Hygiene, 2008, 78, 241-247.
9. JIMA D., TESFAYE G., MEDHIN A., KEBEDE A., ARGAW D. & BABANIYI O. Efficacy of sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in Ethiopia. East African Medical Journal, 2005a, 82, 391-395.
10. JIMA D., TESFAYE G., MEDHIN A., KEBEDE A., ARGAW D. & BABANIYI O. Safety and efficacy of artemether-lumefantrine in the treatement of uncomplicated falciparum malaria in Ethiopia. East African Medical Journal, 2005b, 82, 387-390.
11. KADDOURI H., DJIMDE A., DAMA S., KODIO A., TEKETE M., HUBERT V., KONE A., MAIGA H., YATTARA O., FOFANA B., SIDIBE B., SANGARE C.P., DOUMBO O. & LE BRAS J. Baseeline in vitro efficacy of ACT component drugs on Plasmodium falciparum clinical isolates from Mali. International Journal of Parasitology, 2008, 38, 791-798.
12. KORENROMP E.L., WILLIAMS B.G., Goirws E., DYE C. & SNOW R.W, Measurement of trends in childhood malaria mortality in Africa: an assessment of progress toward, targets based on verbal autopsy. Lancet Infectious Diseases, 2003, 3, 349-358.
13. LEFEVRE G., LOOAREESLWAN S., TREEPRASERTSUK S., KRUDSOOD S., SILACHAMROON U., GATHMANN L., MULL R. & BAKSHI R. A clinical and phamiacokinetic trial of six doses of artemetherlumefantrine for multidrug-resistant Plasmodium falciparum malaria in Thailand. American Journal of Tropical Medicine and Hygiene, 2001, 64, 247-256.
14. MAKANGA M., PREMJI Z., FALADE C, KARBWANG J., MUELLER E., ANDRIANO K., HUNT P. & IBARRA D.P. Efficacy and safety of the six-dose regimen of artemether-lumefantrine in pediatrics with uncomplicated Plasmodium falciparum malaria: A pooled analysis of individual patient data. American Journal of Tropical Medicine and Hygiene, 2006, 74, 991-998.
15. MENARD D., RATSIMBASOA A., RANDRIANARIVELOJOSIA M., RABARIJAONA L.P., RAHARIMALALA L., DOMARLE O., RANDRIANASOLO L., RANDRIAMANANTENA A., JAHEVITRA M., ANDRIANTSOANIRINA V., RASON M.A., RAHERINJAFY R., RAKOTOMALALA E., TUSEO L. & RAVELOSON A. Assessment of the efficacy of antimalarial drugs recommended by the National Malaria Control Programme in Madagascar: up-dated baseline data from randomised and multi-site clinical trials. Malaria Journal, 2008, 7, 55-66.
16. MULENGA M., VAN GEERTRUYDEN J.P., MWANANYANDA L., CHALWE V, MOERMAN F,, CHILENGI R., VAN OVERMEIR C., DUJARDIN J. C & D'ALESSANDRO U. Safety and efficacy of lumefantrine-artemether (Coartem® for the treatment of uncomplicated Plasmodium falciparum malaria in Zambian adults. Malaria Journal, 2006, 5, 73-80.
17. PIOLA P., FOGG C, BAJUNIRWE F., BIRARO S., GRANDESSO F., RUZAGIRA E., BABIGUMIRA J., KIGOZI I., KIGULI J., KYOMUHENDO J., FERRADINI L., TAYLOR W., CHECCHI F. & GUTHMANN JP, Supervised versus unsupervised intake of six-dose artemetherlumefantrine for treatment of acute, uncomplicated Plasmodium falciparum malaria in Mbarara, Uganda: a randomised trial. Lancet, 2005, 365, 14671473.
18. TARGETT G., DRAKELEY C., JAWARA M., VON SEIDLEIN L., COLEMAN R., DEEN J. et al Artesunate reduces but does not prevent post, treatement transmission of Plasmodium falciparum to Anopheles gambiae. Journal of Infectious Diseases, 2001, 183, 1254-1259.
19. TEKLEHAIMANOT A. Chloroquine resistant P. falcparium in Ethiopia. Lancet, 1986, 2, 127-129.
20. TRAPE J.F. The public health, impact of chloroquine resistance in Africa. American Journal of Tropical Medicine and Hygiene, 2001, 64 (1-2 Suppl.), 12-17.
21. UNICEF Ethiopia-Malaria (http://www.unicef.org/ethiopia/ malaria.html)
22. VAN DEN BROEK I., KITZ C., AL ATTAS S., LIBAMA F., BALASEGARAM M. & GUTHMANN J.P. Efficacy of three aitemisinin combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria in the Republic of Congo. Malaria Journal, 2006, 5, 113-122.
23. VAN VUGT M., LOOAREESLTWAN S., WILAIRATANA P., MCGREADY R., VILLEGAS L., GATHMANN I., MULL R., BROCKMAN A., WHITE N.J. & NOSTEN F. Artemether-lumefantrine for the treatment of multidrug-resistant/à/ ciparaw malaria. Transaction of the Royal Society of Tropical Medicine and Hygiene, 2000, 94, 545-548.
24. VAN VUGT M., WILAIRATANA P., GEMPERLI B., GATHMANN I., PHAIPUN L., BROCKMAN A., LUXEMBURGER C., WHITE N.J., NOSTEN F. & LOOAREESLTWAN S. Efficacy of six doses of artemetherlumefantrine (benflumetol) in multidrug-resistant Plasmodium falciparum malaria. American Journal of Tropical Medicine and Hygiene, 1999, 60, 936-942.
25. WINSTANLEY P., WARD S., SNOW R. & BRECKENRIDGE A. Therapy of falciparum malaria in sub-saharan. Africa: from molecule to policy. Clinical Microbiology Review, 2004, 17, 612-637.
26. WORLD HEALTH ORGANIZATION. Antimalarial drug combination therapy: Report of WHO technical consultation. Geneva, April 2001.
27. WORLD HEALTH ORGANIZATION. Assessment and monitoring of antimalarial drug efficacy for the treatment of uncomplicated falciparum malaria. Geneva, 2003.