Early pulmonary findings in a CFTR -/- pig

Pediatric Pulmonology

Volumn 44, Issue SUPPL. 32, 2009, Pages 191-

  Stoltz, David A ^a  

^a UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME PRECURSOR;

ARTICLE; CYSTIC FIBROSIS; DISEASE SEVERITY; EXOCRINE SECRETION; GASTROINTESTINAL DISEASE; INTESTINE INJURY; LIVER INJURY; MECONIUM ILEUS; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE; SWINE;

EID: 70349770705     PISSN: 87556863     EISSN: 10990496     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Rowe SM, Miller S, Sorscher EJ. Cystic fibrosis. New Engl J Med 2005;352:1992-2001.
2. Grubb BR and Boucher RC. Pathophysiology of gene-targeted mouse models for cystic fibrosis. Physiol Rev 1999;79:S193-S214. (Pubitemid 29058915)
3. Davidson DJ and Dorin JR. The CF mouse: an important tool for studying cystic fibrosis. Expert Rev Mol Med 2001;12:1-27.
4. Guilbault C, Saeed Z, Downey GP, Radzioch D. Cystic fibrosis mouse models. Am J Respir Cell Mol Biol 2007;36:1-7.
5. Ibrahim Z, Busch J, Awwad M, Wagner R, Wells K, Cooper DK. Selected physiologic compatibilities and incompatibilities between human and porcine organ systems. Xenotransplantation 2006;13:488-499 (Pubitemid 44592548)
6. Rogers CS, Abraham WM, Brogden KA et al. The porcine lung as a potential model for cystic fibrosis. Am J Physiol Lung Cell Mol Physiol 2008;295:L240-L263.
7. Rogers CS, Hao Y, Rokhlina T, et al. Production of CFTR-null and CFTR-DeltaF08 heterozygous pigs by adeno associated virus-mediated gene targeting and somatic cell nuclear transfer. J Clin Invest 2008;118:1571-1577.
8. Rogers CS, Stoltz DA, Meyerholz DK, et al. Disruption of the CFTR gene produces a model of cystic fibrosis in newborn piglets. Science 2008;321:1837-1841.