Embracing a family-centred response to the HIV/AIDS epidemic for the elimination of pediatric AIDS

Global Public Health

Volumn 4, Issue 4, 2009, Pages 386-401

  DeGennaro, V ^a   Zeitz, P ^b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b Global AIDS Alliance   (United States)

Author keywords

Family centred care; Pediatric HIV AIDS; PMTCT

Indexed keywords

ANTIRETROVIRUS AGENT; COTRIMOXAZOLE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CHILD CARE; CHILD NUTRITION; DIET SUPPLEMENTATION; EARLY CHILDHOOD INTERVENTION; EPIDEMIC; FAMILY CENTERED CARE; FAMILY COUNSELING; HEALTH PROGRAM; HEALTH SERVICE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFANT FEEDING; INFECTION PREVENTION; MALARIA CONTROL; OPPORTUNISTIC INFECTION; PRIORITY JOURNAL; ADOLESCENT; ADULT; AFRICA SOUTH OF THE SAHARA; CHILD; CHILD HEALTH CARE; DISEASE TRANSMISSION; FAMILY HEALTH; FEMALE; INFANT; ORGANIZATION AND MANAGEMENT; PREGNANCY; PREGNANCY COMPLICATION; PRESCHOOL CHILD; STANDARD; VIROLOGY;

ADOLESCENT; ADULT; AFRICA SOUTH OF THE SAHARA; ANTI-RETROVIRAL AGENTS; CHILD; CHILD HEALTH SERVICES; CHILD, PRESCHOOL; FAMILY HEALTH; FEMALE; HIV INFECTIONS; HUMANS; INFANT; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; MATERNAL HEALTH SERVICES; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS;

EID: 70349762955     PISSN: 17441692     EISSN: 17441706     Source Type: Journal    
DOI: 10.1080/17441690802638725     Document Type: Article

References (53)

1. Abrams, E., 2007. MTCT-plus overview, ICAP collaborative pediatric strategic planning workshop, 15-19 April, South Africa.
2. Alcantara, P. and Ribas, F., 2006. UNICEF seal initiative saves and transforms children's lives in Brazil's semi-arid region. Available from: http://www.unicef.org/infobycountry/brazil_37402.html. [Accessed 17 November 2007].
3. Becquet, R., Leroy, V., Ekouevi, D., Viho, I., Castetbon, K., Fassinou, P., Dabis, F., Timite-Konan, M., and ANRS 1201/1202 Ditrame Plus Study Group, 2006. Complementary feeding adequacy in relation to nutritional status among early weaned breastfed children who are born to HIV-infected mothers. Pediatrics, 117 (4), 701-710.
4. Berk, D.R., Falkovitz-Halpern, M.S., Hill, D.W., Albin, C., Arrieta, A., Bork, J.M., Cohan,D., Nilson, B., Petru, A., Ruiz, J., Weintrub, P.S., Wenman, W., Maldonado, Y.A., and California Pediatric HIV Study Group, 2005. Temporal trends in early clinical manifestations of perinatal HIV infection in a population based cohort. Journal of the American Medical Association, 293, 2221-2231.
5. Bolton-Moore, C., Mubiana-Mbewe, M., Cantrell, R., Chintu, M., Stringer, E., Chi, B., Sinkala, M., Kankasa, C., Wilson, C., Wilfert, C., Mwango, A., Levy, J., Abrams, E., Bulterys, M., and Stringer, J., 2007. Clinical outcomes and CD4 cell response in children receiving antiretroviral therapy at primary health care facilities in Zambia. Journal of the American Medical Association, 298, 1888-1899.
6. Bong, C.N., Yu, J.K., Chiang, H.C., Huang, W.L., Hsieh, T.C., Schouten, E.J., Makombe, S.D., Kamoto, K., and Harries, A.D., 2007. Risk factors for early mortality in children on adult fixed-dose combination antiretroviral treatment in a central hospital in Malawi. AIDS, 21 (13), 1805-1810.
7. Braitstein, P., Brinkhof, M.W., Dabis, F., Schechter, M., Boulle, A., Miotti, P., Wood, R., Laurent, C., Sprinz, E., Seyler, C., Bangsberg, D.R., Balestre, E., Sterne, J.A., May, M., and Egger, M., 2006. Mortality of HIV-1 infected patients in the first year of antiretroviral therapy: comparison between low-income and high-income countries. Lancet, 367, 817-824
8. Chintu, C., Bhat, G.J., Walker, A.S., Mulenga, V., Sinyinza, F., Lishimpi, K., Farrelly, L., Kaganson, N., Zumla, A., Gillespie, S.H., Nunn, A.J., Gibb, D.M., and Trial Team, CHAP, 2004. Co-trimoxazole as prophylaxis against opportunistic infections in HIV-infected Zambian children (CHAP): a double-blind randomised placebo-controlled trial. Lancet, 364,1865-1871.
9. Clinton HIV/AIDS Initiative, 2006. President Clinton announces breakthroughs in HIV/ AIDS treatment for children*3-in-1 pill for less than $60 annually and 45% price reductions for other pediatric drugs. Available from: http://www.clintonfoundation.org/113006-nr-cf-hs-ai-ind-pr-wjc-announces-breakthroughs-in-hiv-aids-treatment-for-children.html [Accessed 30 November 2006].
10. Cooper, E.R., Charurat, M., Mofenson, L., Hanson, I.C., Pitt, J., Diaz, C., Hayani, K., Handelsman, E., Smeriglio, V., Hoff, R., and Blattner, W., 2002. Combination antiretroviral strategies for the treatment of pregnant HIV-1 infected women and prevention of perinatal HIV-1 transmission. Journal of Acquired Immune Deficiency Syndromes, 29, 484-494.
11. Costa, C., 2007. Models to routinely & actively offer HAART to eligible pregnant women, ICAP collaborative pediatric strategic planning workshop, 15 19 April, South Africa. Creek, T., 2006. Successful introduction of infant DBS PCR testing in Botswana's PMTCT programme, Forum for Collaborative HIV Research, 9 February, Denver, CO.
12. DeCock, K., Fowler, M.G., Mercier, E., de Vincenzi, I., Saba, J., Hoff, E., Alnwick, D.J., Rogers, M., and Shaffer, N., 2000. Prevention of mother-to-child HIV transmission in resource-poor countries. Journal of the American Medical Association, 283 (9), 1175-1182.
13. DeGennaro, V., 2006. Survey of service delivery organisations reveals current state of pediatric HIV/AIDS and the failure to treat children. In: 15th annual global health education consortium conference, 19-21 April, Toronto, Canada.
14. de Paoli, M., Manongi, R., and Klepp, K.I., 2004. Factors influencing acceptability of voluntary counselling and HIV-testing among pregnant women in Northern Tanzania. AIDS Care, 16 (4), 411-425.
15. Dourado, I., Veras, M., Barreira, D., and deBrito, A., 2006. AIDS epidemic trends after the introduction of antiretroviral therapy in Brazil. Revista de Saude Publica, 40, 9-17.
16. El-Sadr, W.M., Rabkin, M., Abrams, E.J., Hoos, D., Berkman, A., Myer, L., Hardy, T.W., and Rosenfield, A., 2004. Successful enrollment of families with HIV in the MTCT-plus initiative. In: International conference on AIDS. July, Bangkok, Thailand.
17. George, E., Noël, F., Bois, G., Cassagnol, R., Estavien, L., Rouzier Pde, M., Verdier, R.I., Johnson, W.D., Pape, J.W., Fitzgerald, D.W., and Wright, P.F., 2007. Antiretroviral therapy for HIV-1 infected children in Haiti. Journal of Infectious Disease, 195, 1411-1418.
18. Global Partners Forum, 2005. Call to action: towards an HIV-free and AIDS-free generation, Abuja, Nigeria. Available from: http://www.unfpa.org/upload/lib_pub_file/523_filename_abuja_call-to-action.pdf [Accessed 3 December 2007].
19. Kanshana, S. and Simonds, R.J., 2002. National programme for PMTCT in Thailand: successful implementation and lessons learned. AIDS, 16 (7), 953-959.
20. Khan, H., 2007a. India: are PPTCT programmes an entry point to other HIV and reproductive health services? Washington, DC: Horizon's Campaign.
21. Khan, H., 2007b. Repositioning postnatal care: baseline results from Swaziland, a high HIV prevalence environment. Washington, DC: Horizon's Campaign.
22. Krasovec, K., 1991. The implications of poor maternal nutritional status during pregnancy for future lactational performance. Journal of Tropical Pediatrics, 37 (October Suppl.), S3-S10.
23. Matida, L.H., Marcopito, L.F., Succi, R.C., Marques, H.H., Della Negra, M., Grangeiro, A., and Hearst, N., 2004. Improving survival among Brazilian children with perinatally- acquired AIDS. Brazilian Journal of Infectious Disease, 8 (6), 419-423.
24. Mermin, J., Ekwaru, J.P., Liechty, C.A., Were, W., Downing, R., Ransom, R., Weidle, P., Lule, J., Coutinho, A., and Solberg, P., 2006. Effect of co-trimoxazole prophylaxis, antiretroviral therapy, and insecticide-treated bednets on the frequency of malaria in HIV-1-infected adults in Uganda: a prospective cohort study. Lancet, 367, 1256-1261.
25. Mermin, J., Lule, J., Ekwaru, J.P., Downing, R., Hughes, P., Bunnell, R., Malamba, S., Ransom, R., Kaharuza, F., Coutinho, A., Kigozi, A., and Quick, R., 2005. Cotrimoxazole prophylaxis by HIV-infected persons in Uganda reduces morbidity and mortality among HIV-uninfected family members. AIDS, 19, 1035-1042.
26. NACO, 2006. An overview of the spread and prevalence of HIV/AIDS in India. Available from: http://www.nacoonline.org/facts_overview.html [Accessed 23 August 2007].
27. Nash, D., Korves, C., Elul, B., Rabkin, M., Lima, J., Macharia, J., Hoos, D., Ellerbrock, T., and El Sadr, W., 2007. Age and sex distributions of patients enrolled in HIV care and treatment programmes compared with that of the HIV epidemic in 7 sub-Saharan African countries. In: Fourth annual HIV/AIDS implementers' meeting, June, Kigali, Rwanda.
28. Nash, D., Korves, C., and Saito, S., 2008. Characteristics of facilities and programmes delivering HIV care and treatment services are associated with loss to follow-up rates in programmes from 7 sub-Saharan African Countries. In: Fifteenth conference on retroviruses and opportunistic infections, February 2008 Boston, [abstract 838]. Available from: http://www.retroconference.org/2008/Abstracts/33224.htm [Accessed 5 April 2008].
29. Newell, M.L., Coovadia, H., Cortina-Borja, M., Rollins, N., Gaillard, P., and Dabis, F., 2004. Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis. Lancet, 364, 1236-1243.
30. Nogueira, S., Abreu, T., Oliveira, R., Araújo, L., Costa, T., Andrade, M., Garcia Pisc, F., Machoda, A., Rodrigues, K., Mercadante, E.R., Fernandes, I., Sapia, C., Lambert, J., 2001. Successful prevention of HIV transmission from mother to infant in Brazil using a multidisciplinary team approach. Brazilian Journal of Infectious Disease [online], 5 (2), 7886. ISSN 1413-8670.
31. Office of Global AIDS Coordinator, 2008. The power of partnerships: The President's Emergency Plan for AIDS Relief Fourth Annual Report to Congress, Office of the United States Global AIDS Coordinator. Available from: http://www.pepfar.gov/press/fourth_annual_report/ [Accessed 5 April 2008].
32. Okubamichael, E.A., Ntumy, R., Hairston, A.F., Mote, M., Costa, C., and Abrams, E., 2007. Integrating PMTCTof HIV and HIV/AIDS care and treatment services in antenatal clinics: Maseru, Lesotho. In: Fourth annual HIV/AIDS implementers' meeting. June, Kigali, Rwanda.
33. Plipat, T., Naiwatanakul, T., Rattanasuporn, N., Sangwanloy, O., and Amornwichet, P., 2007. Reduction in mother-to-child transmission of HIV in Thailand, 2001 2003: results from population-based surveillance in six provinces. AIDS, 21 (2), 145-151.
34. Potter, D., Goldenberg, R.L., Chao, A., Sinkala, M., and Degroot, A., 2007. Do targeted HIV programmes improve overall care for pregnant women? Antenatal syphilis management in Zambia before and after implementation of PMTCT programmes. Journal of Acquired Immune Deficiency Syndromes, 47 (1), 79-85.
35. Reddi, A., Leeper, S.C., Grobler, A.C., Geddes, R., France, K.H., Dorse, G.L., Vlok, W.J., Mntambo, M., Thomas, M., Nixon, K., Holst, H.L., Karim, Q.A., Rollins, N.C., Coovadia, H.M., and Giddy, J., 2007. Preliminary outcomes of a paediatric highly active antiretroviral therapy cohort from KwaZulu-Natal, South Africa. BioMed Central Pediatrics, 17, 7-13.
36. Rutenberg, N., Siwale, M., Kankasa, C., Nduati, R., Ngacha, D.M., Oyieke, J., Geibel, S., and Kalibala, S., 2003. Family planning and PMTCT services: examining interrelationships, strengthening linkages, horizons research summary. Washington, DC: Population Council.
37. Sherer, R., Stieglitz, K., Narra, J., Jasek, J., Green, L., Moore, B., Shott, S., and Cohen, M.,2002. HIV multidisciplinary teams work: support services improve access to and retention in HIV primary care. AIDS Care, 14 (Suppl. 1), S31-S44.
38. Sripipatana, T., Spensley, A., Miller, A., McIntyre, J., Sangiwa, G., Sawe, F., Jones, D., and Wilfert, C.M., 2007. Site-specific interventions to improve PMTCT of HIV programmes in less developed settings. American Journal of Obstetrics and Gynecology, 197 (3), 107-112.
39. UNAIDS, 2006. Report on Global AIDS Epidemic. Available from: http://www.unaids.org/en/KnowledgeCentre/HIVData/GlobalReport/Default.asp [Accessed 16 August 2007].
40. UNICEF, 2007. Children and AIDS: a stocktaking report. Available from: http://data.unaids.org/pub/Report/2007/20060116_stocktaking_report.pdf [Accessed 16 August 2007].
41. UNICEF, 2008. Children and AIDS: second stocktaking report. Available from: http://www.unicef.org/aids/files/ChildrenAIDS_SecondStocktakingReport.pdf [Accessed 3 April 2008].
42. UNITAID, 2007. HIV/AIDS. Available from: http://www.unitaid.eu/hiv/aids.html [Accessed 16 August 2007].
43. Villamor, E., Mbise, R., Spiegelman, D., Hertzmark, E., Fataki, M., Peterson, K.E., Ndossi,G., and Fawzi, W.W., 2002. Vitamin A supplements ameliorate the adverse effect of HIV-1, malaria, and diarrheal infections on child growth. Pediatrics, 109, e1-e10.
44. Violari, A., Cotton, M., Gibb, D., Babiker, A., Steyn, J., Jean-Philippe, P., and McIntyre, J., 2007. ART initiated before 12 weeks reduces early mortality in young HIV-infected infants: evidence from the Children with HIV Early Antiretroviral Therapy (CHER) Study. In: 4th International AIDS Society Conference. July, Sydney, Australia.
45. Walker, A.S., Mulenga, V., Ford, D., Kabamba, D., Sinyinza, F., Kankasa, C., Chintu, C., and Gibb, D.M., 2007. The impact of daily cotrimoxazole prophylaxis and antiretroviral therapy on mortality and hospital admissions in HIV-infected Zambian children. Clinical Infectious Diseases, 44 (10), 1361-1367.
46. Walker, N., 2004. Global estimates relevant to Pediatric AIDS. WHO technical consultation, 3-4 November,Geneva, Switzerland.
47. Walter, J., Mwiya, M., Scott, N., Kasonde, P., Sinkala, M., Kankasa, C., Kauchali, S., Aldrovandi, G.M., Thea, D.M., and Kuhn, L., 2006. Reduction in preterm delivery and neonatal mortality after the introduction of antenatal cotrimoxazole prophylaxis among HIV-infected women with low CD4 cell counts. Journal of Infectious Diseases, 194 (11), 1510-1518.
48. WHO, 2006a. Consensus statement, WHO HIV and infant feeding technical consultation held on behalf of the inter-agency task team on prevention of HIV infections in pregnant women, mothers and their infants, 25-27 October, Geneva.
49. WHO, 2006b. The 3 by 5 initiative: AIDS treatment for children. Available from: http://www.who.int/3by5/paediatric/en/index.html [Accessed 16 August 2007].
50. WHO, 2007. Antiretroviral therapy of HIV infection in infants and children in resource- limited settings: towards universal access. Available from: http://www.who.int/hiv/pub/guidelines/WHOpaediatric.pdf [Accessed 28 November 2007].
51. WHO/UNAIDS, 2007a. AIDS epidemic update. Available from: http://www.data.unaids.org/pub/EPISlides/2007/2007_epiupdate_en.pdf [Accessed 16 August 2007].
52. WHO/UNAIDS, 2007b. Towards universal access: scaling up priority HIV/AIDS interventions in the health sector. Available at: http://www.who.int/hiv/pub/towards_universal_access_report_2008.pdf [Accessed 2 June 2008].
53. World Food Programme, 2006. World food programme urges more focus on nutrition in fight against HIV/AIDS. Available from: http://www.medicalnewstoday.com/articles/49794.php [Accessed 5 April 2008].